Search
Now showing items 1-10 of 12
Physical properties of shellac material used for hot melt extrusion with potential application in the pharmaceutical industry
(MDPI, 2021-10-28)
Hot melt extrusion offers an efficient way of increasing the solubility of a poorly soluble
drug. Shellac has potential as a pharmaceutical matrix polymer that can be used in this extrusion
process, with further advantages ...
Effect of thermal annealing on a bilayer polyvinyl alcohol/polyacrylic acid electrospun hydrogel nanofibres loaded with doxorubicin and clarithromycin for a synergism effect against osteosarcoma cells
(Elsevier, 2021-08-02)
Polyvinyl alcohol/polyacrylic acid (PVA/PAA) bilayer hydrogel nanofibres were successfully fabricated by
electrospinning and physically crosslinked via heat treatment. The effects of the thermal annealing
process on the ...
Hybrid manufacturing 3D printing and injection moulding in the pursuit of mass customization
(Athlone Institute of Technology, 2020-06)
Project Overview:
Mass customization is a marketing and manufacturing technique which combines the flexibility and personalization of custom-made products with the low unit costs associated with mass production. The ...
Influence of extrusion screw speed on the properties of halloysite nanotube impregnated polylactic acid nanocomposites
(De Gruyter, 2021)
Poly (lactic acid)/halloysite nanotube (PLA/HNT)
nanocomposites have been studiedextensively over the past
fewyears owing to the interesting properties of the polymer,
PLA, and the nanoclay, HNT, individually and as ...
An ensemble machine learning method for microplastics identification with FTIR spectrum
(Elsevier, 2022-06-20)
Microplastics (MPs) (size < 5 mm) marine pollution have been investigated and monitored by many researchers
and found in many coasts around the world. These toxic chemicals make their way into human diet through food ...
A novel star-shaped Schiff base compound: synthesis, properties and application in w-LEDs
(Elsevier, 2022-03-08)
A novel star-shaped Schiff base compound (3) was designed, synthesized and characterized. The thermal stability of 3 was measured. The photophysical properties and solvent effects of 3 were investigated and further analyzed ...
A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix
(MDPI, 2020-12-06)
This study was performed to develop an adjuvant therapy in the form of a self-administered
vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to
reduce relapse by eradicating ...
Development of a new bone scaffold for the treatment of large bone defects
(Technological University of the Shannon Midlands Midwest, 2022)
Large bone defects remains a major problem in orthopaedic surgery despite these advances in medical techniques. To
date, autogenous bone grafting is still commonly therapeutic standard. However, it presents some ...
Hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded delivery system
(TUS Midlands Midwest, 2022)
Cardiovascular diseases (CVDs) are the number 1 cause of death
globally. Fenofibrate has been shown an excellent treating effect
on CVDs. However, Fenofibrate is a neutral, lipophilic compound
that is practically insoluble ...
"My heart, your heart"; hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded drug delivery system
(Athlone Institute of Technology, 2020-06)
Cardiovascular diseases (CVDs) are the number 1 cause
of death globally. Fenofibrate has been shown an
excellent treating effect on CVDs. However, Fenofibrate
is a neutral, lipophilic compound that is practically
insoluble ...