Research, Innovation & Enterprise AIT
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Copyright: All material deposited in the repository must be compliant with Irish copyright legislation. Please refer to: http://www.irishstatutebook.ie/2000/en/act/pub/0028/index.html For items where publisher agreements exist, publishers’ policies must be honoured. A list of publishers’ copyright and self-archiving policies can be found on the Sherpa-Romeo site http://www.sherpa.ac.uk/romeo/ . The author must contact the publisher directly if the publisher is not listed on that site or if written permission to deposit material in a repository is sought. The author must be clear on whether the publisher allows a pre-print, post -print or publisher final version to be added to the repository. Sherpa- Romeo defines pre-prints as being the version of the paper before peer review and post-prints as being the version of the paper after peer-review, with revisions having been made. http://www.irishstatutebook.ie
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Recent Submissions
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Titanium-Niobium (Ti-xNb) alloys with high Nb amounts for applications in biomaterials
(Scielo, 2020-11-10)The present study produced binary titanium-niobium alloys Ti-xNb with high niobium percentage (x = 50, 80 e 90 wt.%) aiming to apply it as a base material in osseous implant devices. The produced TiNb alloys presented a ... -
Production of polyhydroxybutyrate (PHB) and factors impacting its chemical and mechanical characteristics
(MDPI, 2020-12-04)Plastic pollution is fueling the grave environmental threats currently facing humans, the animal kingdom, and the planet. The pursuit of renewable resourced biodegradable materials commenced in the 1970s with the need for ... -
β-glucan metabolic and immunomodulatory properties and potential for clinical application
(MDPI, 2020-12-10)β-glucans are complex polysaccharides that are found in several plants and foods, including mushrooms. β-glucans display an array of potentially therapeutic properties. β-glucans have metabolic and gastro-intestinal effects, ... -
A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix
(MDPI, 2020-12-06)This study was performed to develop an adjuvant therapy in the form of a self-administered vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to reduce relapse by eradicating ... -
Sustainable antimicrobial polymeric food packaging and anti-infection medical catheter preparation using antimicrobial peptide and Ag+ nanoreservoir formulations
(Athlone Institute of Technology, 2020-06)New antimicrobial interventions are urgently required to combat rising global health and medical infection challenges. Here, an innovative antimicrobial technology, providing price competitive alternatives to antibiotics ... -
Characterisation and in vivo evaluation of Araucaria angustifolia pinhão seed coat nanosuspension as a functional food source
(Royal Society of Chemistry, 2020-10-08)Araucaria angustifolia seeds are culturally important from South America; however, the seed coat is generally discarded and have yet to find a beneficial commercial impact. We propose a new formulation to the usage of ... -
Antioxidant, antibacterial and antitumoral activities of kraft lignin from hardwood factionated by acid precipitation
(Elsevier, 2020-11-10)Kraft lignin, so far useful for energy generation, has been gathering considerable attention as an alternative material to replace fossil-based resources mainly due to its high phenolic content. However, the wide molecular ... -
Development of novel PVA-based nanoparticles for delivery system for bone cancer applications
(Athlone Institute of Technology, 2020-06)Osteosarcoma is one of the most frequent bone cancers with almost 30% of patients developin metastasis [1,2]. Further study is needed to develop new drugs that avoid metastasis. There is experimental evidence that chalcones, ... -
Yerba mate extract in microfibrillated cellulose and corn starch films as a potential wound healing bandage
(MDPI, 2020-11-27)Microfibrillated cellulose films have been gathering considerable attention due to their high mechanical properties and cheap cost. Additionally, it is possible to include compounds within the fibrillated structure in ... -
Smart contract driven resource management for edge computing
(Athlone Institute of Technology, 2020-06)Edge computing has witnessed a rapid growth in the past few years as more and more and resources are getting connected to the Internet. The Internet is not gaining any benefits from the current implementation of ad hoc ... -
Estimating the frequency of genomic polymorphisms associated with meat quality in Irish beef cattle
(Athlone Institute of Technology, 2020-06)The calpain (CAPN) and calpastatin (CAST) genes play significant roles in meat tenderness (Casas et al., 2005). Identification and estimation of the frequency of DNA mutations involved in meat tenderness would not only ... -
Development of a versatile monitoring technique for real-time protein activity tracking within cellular environment and biomimetic tissue engineering scaffold systems
(Athlone Institute of Technology, 2020-06)Crowded cellular environments with complex and intricate molecular interactions underpin biological processes. High biological noise is intrinsic within these biological systems, and this poses critical challenges to ... -
Production and testing of the flat faced tablets via overpriting of injection moulded tablet bases
(Athlone Institute of Technology, 2020-06)The pharmaceutical industry is exploring the realization of tailored dosage forms for individual patients to provide precision medicine. My supervisors have previously used a hybrid manufacturing technique that overmoulded ... -
Pulsed ultraviolet-light technology and ecoinnovations for safeguarding consumer health and fragile seafood industry from norovirus outbreaks
(Athlone Institute of Technology, 2020-06)Contamination of water and food are responsible by many outbreaks and deaths worldwide, caused by failures in production, ineffective disinfection techniques, proximity to sources of contamination, and human intervention ... -
Mucoadhesive bilayer vaginal tablet as a potential treatment for cervical cancer
(Athlone Institute of Technology, 2020-06)Cervical cancer is a cancer of the cells of the cervice. It is the 2nd most common cancer affecting women. >270,000 die from it annually. >5000,000 women worldwide are diagnosed. -
Real-time sterilization microbiology - role of flow cytometry
(Athlone Institute of Technology, 2020-06)Sterile medical devices provide critical care and diagnostic applications where sterility is validated by demonstrating the inactivation of reference Biological Indicators (BIs). However, BI’s are qualified using conventional ... -
Evaluation of ethereum end-to-end transaction
(Athlone Institute of Technology, 2020-06)Ethereum is a conventional but evolving blockchain approach to support smart contract by enabling Turingcomplete computations at miners. With smart contract as a back-end support, anyone can publish their Decentralize ... -
"My heart, your heart"; hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded drug delivery system
(Athlone Institute of Technology, 2020-06)Cardiovascular diseases (CVDs) are the number 1 cause of death globally. Fenofibrate has been shown an excellent treating effect on CVDs. However, Fenofibrate is a neutral, lipophilic compound that is practically insoluble ... -
Long-term release rate of a nutritional supplement from a biodegradable polymer matrix
(Athlone Institute of Technology, 2020-06)For the purposes of ruminant nutrition, a 6-month timeframe is the ideal amount of time for the delivery of trace element and minerals. As a starting element, copper was chosen as it is the most commonly observed trace ... -
Antimicrobial films containing green synthesised zinc oxide nanoparticles for biomedical applications
(Athlone Institute of Technology, 2020-06)Synthetic biomaterials have been vastly investigated for different biomedical applications such as wound healing adhesives, implant devices and drug delivery systems. The effort on this field of study promoted the ...
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