Large bone defects remains a major problem in orthopaedic surgery despite these advances in medical techniques. To
date, autogenous bone grafting is still commonly therapeutic standard. However, it presents some limitations
associated with available bone volume, other complications and severe morbidity at the donor site. Bone tissue
engineering has become one of promising methods to treat large bone defect due to its flexibility, biocompatible and
osteoinductive. Composite scaffold with different formulations were prepared by the UV cross-link, and the
properties of scaffolds were characterised by Fourier transform infrared (FTIR) spectroscopy and compression testing.
The aim of this project is using biodegradable Composite scaffold to stimulate bone regeneration by controlling the
releasing of active pharmaceutical ingredients