Now showing items 1-20 of 32

    • Oriented polymeric sheets exhibiting dichroism and articles containing the same. 

      Kumar, Anil; Foller, Peter C.; Park, David; Devine, Declan; Bastiaansen, C.W.M.; Tennissen, J.P.; Cloonan, Martin; Higginbotham, Clement L. (2007-12-20)
      Provided is an oriented polymeric sheet comprising a photochromic-dichroic material, wherein the sheet exhibits dichroism in an activated state. Also provided is a multilayer composite comprising at least a support layer ...
    • Smart hydrogels: therapeutic advancements in hydrogel technology for smart drug delivery applications. 

      de Lima, Gabriel Goetten; Kanwar, Diwakar; Macken, Derek; Geever, Luke; Devine, Declan M.; Nugent, Michael J.D. (Wiley, 2015-12)
      Hydrogels are a fusion of solid and liquid phases which closely mimic biological tissue. As such they have enormous potential for drug delivery systems as they are biocompatible and may be tailored to specific applications. ...
    • Electrospinning of hydrogels for biomedical applications 

      de Lima, Gabriel Goetten; Lyons, Sean; Devine, Declan M.; Nugent, Michael J.D. (Springer Nature, 2018)
      The field of biomedical applications for hydrogels requires the development of nanostructures with specific controlled diameter and mechanical properties. Nanofibers are ideally candidates for these advanced requirements, ...
    • Degradable polymer nanocomposites for fused filament fabrication applications 

      Healy, Andrew V.; Geever, Luke M.; Devine, Declan M.; Lyons, John G. (Athlone Institute of Technology, 2018-04-24)
      The use of plastics in everyday life has increased dramatically during the course of the 20th and 21st century which is primarily due to the characteristics plastics offer in the development of new products to meet the ...
    • The influence of mechanical stretching and freeze-thaw processing on the properties of polyvinyl alcohol hydrogels for drug delivery applications 

      Chee, Bor Shin; De Lima, Gabriel G.; Devine, Declan M.; Nugent, Michael J.D. (Athlone Institute of Technology, 2018-04-24)
      The study describes the development of physically cross-linked polyvinyl alcohol (PVA) hydrogels using uniaxial orientation via freeze-thawing (F/T). Although cryogels have shown significant improvements in long-term ...
    • Development of high strength nanocomposite for biodegradable stents 

      Venkatesh, Chaitra; Chen, Yuanyuan; Cao, Zhi; Brennan, Shane; Major, Ian; Lyons, John G.; Devine, Declan M. (Athlone Institute of Technology, 2018-04-24)
      The use of biodegradable polymer materials are considered to be good alternatives in urology (Donohue et. al. 2018), cardiovascular (Brie et. al. 2016) and tracheal airway stenosis which provide support before it is absorbed ...
    • Enhancing the bioavailability of hydrophobic drugs using hot melt extrusion 

      Devine, Declan M.; Higginbotham, Clement; Geever, Luke M.; Coffey, Conor (Athlone Institute of Technology, 2018-04-24)
      Many existing drugs (as well as new revelations) in the pharmaceutical industry bear a distinct disadvantage in the sense that they are not water soluble, displaying low bioavailability values and consequently a reduced ...
    • 3D printed end of arm tooling (EOAT) of a robotic arm 

      Ong U Jing, Daniel; Lyons, Sean; Devine, Declan (Athlone Institute of Technology, 2018-04-24)
      This research furthers the practice of designing and manufacturing an EOAT for low weight applications by utilising additive manufacturing (“3D Printing”) techniques to decrease energy consumption via tool weight savings ...
    • Structure response for cellulose-based hydrogels via characterization techniques. 

      de Sá, Marcelo Jorge Cavalcanti; de Lima, Gabriel Goetten; Segundo, Francisco Alipio de Sousa; Nugent, Michael J.D. (Springer, 2019)
      Hydrogels are three-dimensional crosslinked polymeric networks capable of imbibing substantial amounts of water or biological fluids and are widely used in biomedical applications, especially in pharmaceutical industry as ...
    • Tailoring surface properties from nanotubes and anodic layers of titanium for biomedical applications. 

      de Lima, G.G.; da Luz, Aline Rossetto; Pereira, Bruno Leandro; Szez, Eduardo Mioduski; de Souza, Gelson Biscaia; Lepienski, Carlos Mauricio; Kuromoto, Neide Kazue; Nugent, Michael J.D. (Woodhead Publishing, 2019)
      The following chapter gives an overview of the anodic layers and nanotubes produced with plasma electrolytic oxidation. An introduction into the mechanisms involved in producing these nanofilms, such as the required ...
    • Electrospun hydrogels composites for bone tissue engineering. 

      Chee, Bor Shin; de Lima, Gabriel Goetten; Devine, Declan; Nugent, Michael J. D. (Woodhead Publishing, 2019)
      Electrospinning is one of the foremost nanotechnology applications to fabricate bone tissue engineering scaffolds with sizes in the nanometer range. It is regarded as a versatile, inexpensive, and relatively simple methodology ...
    • Polymer based additive manufacturing historical developments, process types and material considerations. 

      Pollack, Steven; Venkatesh, Chaitra; Neff, Martin; Hu, Guang; Fuenmayor, Evert; Lyons, John G.; Major, Ian; Devine, Declan M. (Springer Nature, 2019)
      3D printing is a manufacturing technique where parts are built in a layer-by-layer fashion. The earliest embodiments were based on generating successive layers of solidified materials at the air liquid interface through ...
    • Electrospun natural polysaccharide for biomedical applications. 

      Chee, Bor Shin; Nugent, Michael (Elsevier, 2019-07-27)
      Electrospinning is a simple and versatile technique in nanotechnology for fabricating nanofibers scaffolds for tissue regenerations, drug delivery systems, wound healing, and cancer therapy. This chapter provides a synopsis ...
    • Orthopaedic 3D printing in orthopaedic medicine. 

      Brennan Fournet, Margaret; Azman, Farah Alwani Binti; Günbay, Suzan; Chen, Yuanyuan; Devine, Declan M. (Springer, 2019-09-17)
      Orthopaedic surgeries are commonly extremely challenging, and innovations are required to overcome a series of recognised difficulties and improve patient outcomes. Complications, in particular, the high occurrence of ...
    • Preclinical assessment of biomimetic and bioactive bone regeneration scaffold in femoral condyle defect of Sprague Dawley rats. 

      Azaman, Farah Alwani; Brennan Fournet, Margaret (Athlone Institute of Technology, 2020)
      A fabricated biomimetic bone scaffold, incorporating osteogenic factors, presents a promising alternative to traditional autologous and allogeneic bone fracture treatments. Here, the principles of biology and engineering ...
    • Evaluation of the efficacy of lipid core nanoemulsions containing temozolomide coupled to ferrocenes in the treatment of Glioblastomas 

      Henn, Jeferson G.; Ferro, Matheus B.; Steffens, Luiza; da Rosa, Ricardo G.; Aguirre, Tanira A.S.; Nugent, Michael; Moura, Dinara J. (Athlone Institute of Technology, 2020)
      Glioblastoma (GB) is the most common and aggressive neoplastic brain tumor, and its treatment has proved to be a challenge. For decades its therapy has been based on the use of temozolomide (TMZ), but the survival rate ...
    • Development of biphasic drug delivery PVA/propolis electrospun nanofibres 

      Chee, Bor Shin; Sampio, Viviane Seba; Nugent, Michael (Athlone Institute of Technology, 2020-06)
      The integration of nanotechnology into biomedical applications is called “nanomedicine”. Nanomedicine has the ability to change properties of materials at the molecular and atomic level [1]. Numerous methods have been ...
    • The development of novel smart colour change polymer materials via various melt processing techniques 

      Breheny, Colette; Geever, Luke; Geever, Joseph (Athlone Institute of Technology, 2020-06)
      Smart polymers or stimuli-responsive polymers undergo large reversible changes, whether physical or chemical, in their properties as a consequence of small environmental variations. They can respond to a single stimulus ...
    • The development of novel bioresorbable medical devices for treating diseases of the anal canal 

      Fitzpatrick, Daniel P.; Brady, Damien; Kealey, Carmel; Gatley, Noel (Athlone Institute of Technology, 2020-06)
      Anal abscesses and fistulae in ano are the most prominent diseases of the anal canal Abscesses are pockets of pus caused by accumulating bactera whereas fistulae in ano are hollow tunnels that protrude from the wall of ...
    • Development of smart 4-D materials utilising novel self assembly polymers 

      Halligan, Elaine; Hayes, Conor; Geever, Luke (2020-06)
      4D printing is a technique that uses a 3 D printer to create objects that change their shape overtime 4 D printing involves the use of smart materials that will transform when exposed to an external stimuli These can ...