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Composite cryogels for dual drug delivery and enhanced mechanical properties.
(Wiley, 2018-04)
In this study, we present a simple and effective process that integrates hydrogels with drugs + ceramics via physical crosslinks resulting in improved mechanical properties. These cryogels have the potential for controlled ...
Micro-injection moulding of poly(vinylpyrrolidone-vinyl acetate) binary and ternary amorphous solid dispersions.
(MDPI, 2019-05)
Micro-injection moulding (µIM) was used for the production of enteric tablets of plasticised
and unplasticised solid dispersions of poly(vinylpyrrolidone-vinyl acetate) (PVPVA), and the effect
of the mechanical and thermal ...
The development of novel polymeric delivery systems for the controlled release of therapeutic agents to prevent the spread of zoonotic diseases
(2022)
The potential for zoonotic transmission - a disease transmitted from animals to people
- of many disease pathogens is a significant concern worldwide. It is estimated that
60 of human emerging infectious diseases, including ...
Faster release of lumen-loaded drugs than matrix-loaded equivalent in polylactic acid/halloysite nanotubes.
(MDPI, 2019-06-15)
Nanocomposite-based drug delivery systems with intrinsic controlled release properties are of great interest in biomedical applications. We report a novel polylactic acid (PLA)/halloysite nanotube (HNT) nanocomposite-based ...
Antimicrobial films containing green synthesised zinc oxide nanoparticles for biomedical applications
(Athlone Institute of Technology, 2020-06)
Synthetic biomaterials have been vastly investigated for
different biomedical applications such as wound healing
adhesives, implant devices and drug delivery systems. The
effort on this field of study promoted the ...
Investigation of the effects of orientation on freeze/thawed Polyvinyl alcohol hydrogel properties.
(Elsevier, 2018-12)
Although hydrogels produced via freeze-thawing (F/T) technique have been thoroughly studied in literature, stretching hydrogels in between freeze-thawing cycles could change its properties and might be modulated for drug ...
Processing stability and the significance of variation in extrusion speeds and temperture on SSB® 55 Pharma Grade Shellac for Oral Drug Delivery
(MDPI, 2017-09-06)
The melt-extrusion process is utilized in the pharmaceutical arena for the manufacturing of a variety of dosage forms and formulations, including solid dispersions. This technology is considered an efficient and continuous ...
Investigation of a novel freeze-thaw process for the production of drug delivery hydrogels
(Springer, 2005-12)
Poly(vinyl alcohol) (PVA) is a water-soluble, biocompatible and biodegradable polymer, which has been widely applied in biomedical fields. In this paper, novel physically cross-linked hydrogels composed of PVA and comprising ...
Development of biphasic drug delivery PVA/propolis electrospun nanofibres
(Athlone Institute of Technology, 2020-06)
The integration of nanotechnology into biomedical applications is called “nanomedicine”. Nanomedicine has the ability to change properties of materials at the molecular and atomic level [1]. Numerous methods have been ...
Development of novel PVA-based nanoparticles for delivery system for bone cancer applications
(Athlone Institute of Technology, 2020-06)
Osteosarcoma is one of the most frequent bone cancers with almost 30% of patients developin metastasis [1,2]. Further study is needed to develop new drugs that avoid metastasis. There is experimental evidence that chalcones, ...