Browsing Technological University of the Shannon: Midlands Midwest by Author "Chee, Bor Shin"
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Antimicrobial PAA/PAH electrospun fiber containing green synthesized zinc oxide nanoparticles for wound healing
Bandeira, Marina; Chee, Bor Shin; Frassini, Rafaele; Nugent, Michael; Giovanela, Marcelo; Roesch-Ely, Mariana; da Silva Crespo, Janaina; Devine, Declan M. (MDPI, 2021-05-27)Wound infections are the main complication when treating skin wounds. This work reports a novel antimicrobial material using green synthesized zinc oxide nanoparticles (ZnONPs) incorporated in polymeric fibers for wound ... -
Boosting bacterial nanocellullose production from chemically recycled post-consumer polyethylene terephthalate
Da Silva Pereira, Everton Henrique; Attallah, Olivia A.; Tas, Cuneyt Erdinc; Chee, Bor Shin; Freitas, Filomena; Lanzagorta Garcia, Eduardo; McAuliffe, Michael A.P.; Mojicevic, Marija; Batista, Maria N.; Reis, Maria A.M.; Brennan Fournet, Margaret (Elsevier, 2024-04)The circular economy is emerging with new sustainable solutions to the ever-growing plastic waste challenge, garnering increasing attention. In this study, the possibility to modify expensive Hestrin–Schramm medium (HS) for ... -
Characterization of gels and films produced from Pinhão seed coat nanocellulose as a potential use for wound healing dressings and screening of Its compounds towards antitumour effects
de Lima, Tielidy A. de M.; de Lima, Gabriel Goetten; Chee, Bor Shin; Henn, Jeferson G.; Cortese, Yvonne J.; Matos, Mailson; Helm, Cristiane V.; Magalhães, Washington L.E.; Nugent, Michael J.D. (MDPI, 2022-07-07)The reuse of agro-industrial waste assumes great importance today. Pinhão is the seed of Araucaria angustifolia, which is native to the mountains of southern Brazil, Paraguay, and Argentina. The coat is a by-product of ... -
Design, development and in vitro quantification of novel electrosprayed everolimus-loaded Soluplus®/Polyvinyl alcohol nanoparticles via stability-indicating HPLC method in cancer therapy
Louis, Lynn; Chee, Bor Shin; McAfee, Marion; Nugent, Michael J.D. (Elsevier, 2023-09-14)Everolimus (RAD001) a mammalian target of rapamycin has been hampered by poor solubility, affecting its dissolution rate, a relationship that extends to low bioavailability. Nanoparticles (NP) based on Soluplus (SOL®) and ... -
Development of biphasic drug delivery PVA/propolis electrospun nanofibres
Chee, Bor Shin; Sampio, Viviane Seba; Nugent, Michael (Athlone Institute of Technology, 2020-06)The integration of nanotechnology into biomedical applications is called “nanomedicine”. Nanomedicine has the ability to change properties of materials at the molecular and atomic level [1]. Numerous methods have been ... -
Development of electrospun PVA nanofibers via freeze-thawing method
Chee, Bor Shin; Wu, Husheng; Zhu, Wenquan; Masood, Unsa; Sampaio, Viviane Seba; Pereira, Bruno Leandro; Nugent, Michael J.D. (Athlone Institute of Technology, 2019)The polyvinyl alcohol (PVA) hydrogels are proven to have the benefits of improving water retention ability, cell attachment and controlled drug release in medical device materials for pharmaceutical applications. Due to ... -
The development of novel PVA hydrogel for biomedical and drug delivery applications
Chee, Bor Shin (Athlone Institute of Technology, 2021-08)Hydrogels have been used widely in biomaterial applications, mainly due to their low interfacial tension, useful swelling properties and high lubricity. In addition to their promising biocompatibility characteristics, ... -
Effect of thermal annealing on a bilayer polyvinyl alcohol/polyacrylic acid electrospun hydrogel nanofibres loaded with doxorubicin and clarithromycin for a synergism effect against osteosarcoma cells
Chee, Bor Shin; de Lima, Gabriel Goetten; de Lima, T.A.M.; Seba, Viviane; Lemarquis, C.; Pereira, Bruno Leandro; Bandeira, Marina; Cao, Zhi; Nugent, Michael J.D. (Elsevier, 2021-08-02)Polyvinyl alcohol/polyacrylic acid (PVA/PAA) bilayer hydrogel nanofibres were successfully fabricated by electrospinning and physically crosslinked via heat treatment. The effects of the thermal annealing process on the ... -
Effect of unidirectional freezing using a thermal camera on polyvinyl (alchohol) for aligned porous cyrogels.
de Lima, Gabriel Goetten; Barbosa, Rêydila Rayenne Caminhas; de Andrade Santos, M.P.; Chee, Bor Shin; Esteves Magalhães, Washington Luiz Esteves; Devine, Declan M.; Nugent, Michael J.D. (Taylor & Francis Online, 2020-03-18)Unidirectional freeze casting for polymers and ceramics has been performed extensively; however, the mechanisms involved in unidirectional freezing are not thoroughly understood and therefore, in this study, polyvinyl ... -
Electrospun drug-loaded and gene-loaded nanofibres: the holy grail of glioblastoma therapy?
Louis, Lynn; Chee, Bor Shin; McAfee, Marion; Nugent, Michael J.D. (MDPI, 2023-06-03)To date, GBM remains highly resistant to therapies that have shown promising effects in other cancers. Therefore, the goal is to take down the shield that these tumours are using to protect themselves and proliferate ... -
Electrospun hydrogels composites for bone tissue engineering.
Chee, Bor Shin; de Lima, Gabriel Goetten; Devine, Declan; Nugent, Michael J. D. (Woodhead Publishing, 2019)Electrospinning is one of the foremost nanotechnology applications to fabricate bone tissue engineering scaffolds with sizes in the nanometer range. It is regarded as a versatile, inexpensive, and relatively simple methodology ... -
Electrospun natural polysaccharide for biomedical applications.
Chee, Bor Shin; Nugent, Michael (Elsevier, 2019-07-27)Electrospinning is a simple and versatile technique in nanotechnology for fabricating nanofibers scaffolds for tissue regenerations, drug delivery systems, wound healing, and cancer therapy. This chapter provides a synopsis ... -
Freeze-thaw electrospun PVA-Dacarbazine nanoparticles: preparation, characterization and anticancer evalution.
Steffens, Luiza; Chee, Bor Shin; Moura, Dinara Jacqueline; Nugent, Michael (Taylor & Francis Online, 2019-06-13)Dacarbazine (DTIC) is an antitumor agent that has limited clinical applications due to its insolubility, instability and toxicity to normal cells. One possibility to achieve controlled release is PVA-based NPs. This work ... -
The influence of mechanical stretching and freeze-thaw processing on the properties of polyvinyl alcohol hydrogels for drug delivery applications
Chee, Bor Shin; De Lima, Gabriel G.; Devine, Declan M.; Nugent, Michael J.D. (Athlone Institute of Technology, 2018-04-24)The study describes the development of physically cross-linked polyvinyl alcohol (PVA) hydrogels using uniaxial orientation via freeze-thawing (F/T). Although cryogels have shown significant improvements in long-term ... -
Investigation of the effects of orientation on freeze/thawed Polyvinyl alcohol hydrogel properties.
Chee, Bor Shin; de Lima, Gabriel Goetten; Devine, Declan M.; Nugent, Michael J. D. (Elsevier, 2018-12)Although hydrogels produced via freeze-thawing (F/T) technique have been thoroughly studied in literature, stretching hydrogels in between freeze-thawing cycles could change its properties and might be modulated for drug ... -
Microfibrillated cellulose films containing chitosan and tannic acid for wound healing applications
Alibadi, Meysam; Chee, Bor Shin; Matos, Mailson; Cortese, Yvonne J.; Nugent, Michael J.D.; de Lima, Tieilidy A. M.; Magalhães, Washingtonn L.E.; de Lima, Gabriel Goetten; Firouzabadi, Mohammadreza Dehghani (Springer, 2021-06-12)The effectiveness of tannic acid as antimicrobial and wound healing for burns have been shown for a century; however, uncontrolled target dosage may result in undesirable side-effects. Remarkably, tannic acid polyphenols ... -
Novel polyvinyl-alcohol microsphere for everolimus delivery for subependymal cell astrocytoma
Louis, Lynn; Chee, Bor Shin; Louis, Noreen; Goetten de Lima, Gabriel; McAfee, Marion (Elsevier, 2023-02-02)Everolimus (EVR) has demonstrated efficacy in treating subependymal giant cell astrocytoma (SEGA) and other tuberous sclerosis (TSC) manifestations. Oral use of EVR is associated with low bioavailability and systemic toxicities ... -
Oxide layer containing apatite formed on Ti-25Nb-25Ta alloy treated by two-step plasma electrolytic oxidation.
Pereira, Bruno Leandro; Beilner, Gregory; Lepienski, Carlos Mauricio; Szameitat, Erico Saito; Kuromoto, Neide Kazue; dos Santos, Leonardo Luis; Chee, Bor Shin; Alves Claro, Anna Paula Rosifini; Mazzaro, Irineu; Nugent, Michael J.D. (Elsevier, 2020-01-25)Hydroxyapatite (HA) is a bioactive calcium phosphate capable of enhancing the implant/bone connection improving osteoconductivity and osseointegration process. However, the HA presents mechanical properties limiting its ... -
The production of a novel poly(vinyl alcohol) hydrogel cryogenic spheres for immediate release using a droplet system.
de Lima, Gabriel Goetten; Chee, Bor Shin; Moritz, Vicente Froés; Cortese, Yvonne J.; Maghalhães, Washington L. E.; Devine, Declan M.; Nugent, Michael J. D. (IOP Science, 2019-06-05)Although freeze-thaw mechanism for producing crosslinked hydrogels is relatively easy and simple, it lacks sufficient integrity and support leading to modifications on its three-dimensional polymeric network arrangement ... -
Ti-25Nb-25Ta alloy treated by plasma electrolytic oxidation in phosphoric acid for implant applications
Beilner, Gregory; Pereira, Bruno Leandro; Lepienski, Carlos Mauricio; de Souza, Gelson Biscaia; da Luz, Aline Rosseto; Szameitat, Erico Saito; Kuromoto, Neide Kazue; Claro, Ana Paula Rosifini Alves; Sampaio, Viviane Seba; Chee, Bor Shin; Nugent, Michael J.D. (Rede Latino-Americana de Materiais, 2021)Among titanium alloys with non-toxic elements, the Ti-25Nb-25Ta alloy has good elastic behavior for applications in osseous implants, biocompatibility, and excellent corrosion resistance. The present study aimed to better ...