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Development of a versatile monitoring technique for real-time protein activity tracking within cellular environment and biomimetic tissue engineering scaffold systems
(Athlone Institute of Technology, 2020-06)
Crowded cellular environments with complex and intricate
molecular interactions underpin biological processes. High
biological noise is intrinsic within these biological systems, and this
poses critical challenges to ...
Modification of hyaluronic acid for stereolithography 3D printing of hydrogel nerve conduits
(Athlone Institute of Technology, 2020-06)
The peripheral nervous system transmits signals from the brain to the limbs and organs of the
body. Peripheral nerve injuries (PNIs) resulting from trauma, illness or cancer affect
approximately 1 million people in Europe ...
Turning agricultural waste into wealth: production of sustainable cellulose for hydroponic farming
(Technological University of the Shannon Midlands Midwest, 2022)
Globally, it is estimated that approximately 998 million of agricultural wasteis produced yearly. This enormous amount of waste has become a matter of great public concern. However, agricultural waste is a natural resource ...
Sustainable antimicrobial polymeric food packaging and anti-infection medical catheter preparation using antimicrobial peptide and Ag+ nanoreservoir formulations
(Athlone Institute of Technology, 2020-06)
New antimicrobial interventions are urgently required to combat rising global health and medical infection challenges. Here, an
innovative antimicrobial technology, providing price competitive alternatives to antibiotics ...
Development of sustainable flexible packaging solutions using novel biodegradable and compostable polymer blends
(BioICEP, 2020-10-19)
Plastic packaging has changed positively the way food products are delivered, reducing
poverty and hunger due to the better protection of the goods, allowing their preservation for
longer times throughout their supply ...
Functionality of gold-edge-coated triangular silver nanoparticles in monitoring extracellular matrix protein conformations in C2C12/MC3T3-E1 culture in the presence of biomimetic bone tissue regeneration scaffolds
(TUS Midlands Midwest, 2022)
In the cellular environment high
noise levels can both mediate and
interfere with cellular functions.The extracellular matrix (ECM)
regulates protein dynamics and
trajectories, which underpin
critical biological ...
Hybrid manufacturing 3D printing and injection moulding in the pursuit of mass customization
(Athlone Institute of Technology, 2020-06)
Project Overview:
Mass customization is a marketing and manufacturing technique which combines the flexibility and personalization of custom-made products with the low unit costs associated with mass production. The ...
The development of novel polymeric delivery systems for the controlled release of therapeutic agents to prevent the spread of zoonotic diseases
(2022)
The potential for zoonotic transmission - a disease transmitted from animals to people
- of many disease pathogens is a significant concern worldwide. It is estimated that
60 of human emerging infectious diseases, including ...
The osteoinduction of C2C12 myoblast cell-line treated with growth factor-incorporated biocomposites
(TUS Midlands Midwest, 2022)
Bone regeneration scaffold serves as an alternative treatment to critical bone defects,
substituting the traditional gold standard autologous bone grafting. A number of
biomaterials and osteogenic growth factors are of ...
Evaluation of the efficacy of lipid core nanoemulsions containing temozolomide coupled to ferrocenes in the treatment of Glioblastomas
(Athlone Institute of Technology, 2020)
Glioblastoma (GB) is the most common and aggressive neoplastic brain tumor, and its treatment has proved to be a challenge.
For decades its therapy has been based on the use of temozolomide (TMZ), but the survival rate ...