Browsing Articles - Bioscience Research Institute (BRI) by Author "Masterson, Kevin"
Now showing items 1-3 of 3
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A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix
Abidin, Ismin Zainol; Rezoagli, Emanuele; Simonassi-Paiva, Bianca; Fehrenbach, Gustavo Waltzer; Masterson, Kevin; Pogue, Robert; Cao, Zhi; Rowan, Neil; Murphy, Emma J.; Major, Ian (MDPI, 2020-12-06)This study was performed to develop an adjuvant therapy in the form of a self-administered vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to reduce relapse by eradicating ... -
Development of a low-temperature extrusion process for production of GRAS bioactive-polymer loaded compounds for targeting antimicrobial-resistant (AMR) bacteria
Masterson, Kevin; Meade, Elaine; Garvey, Mary; Lynch, Mark; Major, Ian; Rowan, Neil J. (Elsevier, 2021-08-10)Antimicrobial resistance (AMR) is recognised globally as one of the greatest threats to human and animal health; thus, discovery of alternative antibacterial agents to address AMR is a priority challenge. This study ... -
Synergy assessment of four antimicrobial bioactive compounds for the combinational treatment of bacterial pathogens
Masterson, Kevin; Major, Ian; Lynch, Mark; Rowan, Neil (MDPI, 2023-08-07)Antimicrobial resistance (AMR) has become a topic of great concern in recent years, with much effort being committed to developing alternative treatments for resistant bacterial pathogens. Drug combinational therapies ...