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Now showing items 21-30 of 43
A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix
(MDPI, 2020-12-06)
This study was performed to develop an adjuvant therapy in the form of a self-administered
vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to
reduce relapse by eradicating ...
Antioxidant, antibacterial and antitumoral activities of kraft lignin from hardwood factionated by acid precipitation
(Elsevier, 2020-11-10)
Kraft lignin, so far useful for energy generation, has been gathering considerable attention as
an alternative material to replace fossil-based resources mainly due to its high phenolic content.
However, the wide molecular ...
Development of biphasic drug delivery PVA/propolis electrospun nanofibres
(Athlone Institute of Technology, 2020-06)
The integration of nanotechnology into biomedical applications is called “nanomedicine”. Nanomedicine has the ability to change properties of materials at the molecular and atomic level [1]. Numerous methods have been ...
Development of novel PVA-based nanoparticles for delivery system for bone cancer applications
(Athlone Institute of Technology, 2020-06)
Osteosarcoma is one of the most frequent bone cancers with almost 30% of patients developin metastasis [1,2]. Further study is needed to develop new drugs that avoid metastasis. There is experimental evidence that chalcones, ...
Yerba mate extract in microfibrillated cellulose and corn starch films as a potential wound healing bandage
(MDPI, 2020-11-27)
Microfibrillated cellulose films have been gathering considerable attention due to their high
mechanical properties and cheap cost. Additionally, it is possible to include compounds within the
fibrillated structure in ...
Long-term release rate of a nutritional supplement from a biodegradable polymer matrix
(Athlone Institute of Technology, 2020-06)
For the purposes of ruminant nutrition, a 6-month timeframe is
the ideal amount of time for the delivery of trace element and
minerals. As a starting element, copper was chosen as it is the
most commonly observed trace ...
Production of polyhydroxybutyrate (PHB) and factors impacting its chemical and mechanical characteristics
(MDPI, 2020-12-04)
Plastic pollution is fueling the grave environmental threats currently facing humans, the animal kingdom, and the planet. The pursuit of renewable resourced biodegradable materials commenced in the 1970s with the need for ...
Evaluation of titanium nitride coatings in bandsaw blades for wood splitting by cold plasma
(Taylor & Francis, 2021-11-06)
Due to the advances in surface treatments, it is possible to obtain excellent cutting tools. However, the field for wood cutting tools still needs to be further investigated. In this work, titanium nitride was deposited ...
Effect of cullulose size-concentration on the structure of polyvinyl alcohol hydrogels.
(Elsevier, 2020-06-11)
Microfibrillated cellulose as a reinforcement agent has been investigated extensively due to their unique characteristics, which can reorder the structure of polymers and hydrogels leading to improved mechanical properties ...
Hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded delivery system
(TUS Midlands Midwest, 2022)
Cardiovascular diseases (CVDs) are the number 1 cause of death
globally. Fenofibrate has been shown an excellent treating effect
on CVDs. However, Fenofibrate is a neutral, lipophilic compound
that is practically insoluble ...