Search
Now showing items 11-20 of 24
A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix
(MDPI, 2020-12-06)
This study was performed to develop an adjuvant therapy in the form of a self-administered
vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to
reduce relapse by eradicating ...
Hyaluronic acid: a review of the drug delivery capabilities of this naturally occurring polysaccharide
(MDPI, 2022-08-23)
The inclusion of physiologically active molecules into a naturally occurring polymer matrix can improve the degradation, absorption, and release profile of the drug, thus boosting the therapeutic impact and potentially ...
Production and testing of the flat faced tablets via overprinting of injection moulded tablet bases
(Technological University of the Shannon Midlands Midwest, 2022)
Conventional drug production assures the merits of maintaining unit
dosage form accuracy, stable dose and invariability among the batches. It
also has a shortcoming that cannot make personalised medicine that could
target ...
Purified β‐glucans from the Shiitake mushroom ameliorates antibiotic‐resistant Klebsiella pneumoniae‐induced pulmonary sepsis
(Society for Applied Microbiology, 2020-07-24)
Bacterial infection remains the main cause of acute respiratory distress syndrome and is a leading cause of death and disability in critically ill patients. Here we report on the use of purified β‐glucan (lentinan) extracts ...
Development of a low-temperature extrusion process for production of GRAS bioactive-polymer loaded compounds for targeting antimicrobial-resistant (AMR) bacteria
(Elsevier, 2021-08-10)
Antimicrobial resistance (AMR) is recognised globally as one of the greatest threats to human and animal health; thus, discovery of alternative antibacterial agents to address AMR is a priority challenge. This study ...
Fused-filament fabrication of PEEK: a review of process-structure-property relationships.
(MDPI, 2020-07-27)
Poly (ether ether ketone) (PEEK) is a high-performance engineering thermoplastic polymer
with potential for use in a variety of metal replacement applications due to its high strength to weight
ratio. This combination ...
β-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in-vitro immunomodulatory and pulmonary cytoprotective effects — Implications for coronavirus disease (COVID-19) immunotherapies.
(Elsevier, 2020-05-11)
Coronavirus pneumonia is accompanied by rapid virus replication, where a large number of inflammatory cell infiltration and cytokine storm may lead to acute lung injury, acute respiratory distress syndrome (ARDS) and death. ...
Mass customization of polylactic acid (PLA) parts via a hybrid manufacturing process
(MDPI, 2022-12-10)
Mass customization is the development of items tailored to specific customers, but
produced at low unit cost in high-volume. In this context, hybrid manufacturing (HM) combines
fused deposition modeling (FDM) and injection ...
A systematic review of mucoadhesive vaginal tablet testing
(AboutScience, 2023-01-16)
Drug administration through the vaginal tract is one of the oldest modalities of pharmacotherapy, and it is also one of the most explored. Since the vaginal cavity has a wide surface area, a plentiful blood supply, and a ...
Pulsed ultraviolet (PUV) disinfection of artifcially contaminated seawater seeded with high levels of pathogen disease indicators as an alternative for the shellfish industry depuration systems
(Springer, 2023-05-08)
The increase in pathogen levels in seawater threatens the safety of entire aquatic ecosystems. Foodborne pathogens can potentially accumulate in shellfish, especially in filter feeders such as bivalves, requiring an efficient ...