Browsing Technological University of the Shannon: Midlands Midwest by Author "Geever, Luke"
Now showing items 1-17 of 17
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The development of novel polymeric delivery systems for the controlled release of therapeutic agents to prevent the spread of zoonotic diseases
Nunes Bezerra, Gilberto; Geever, Luke; Geever, Joe (2022)The potential for zoonotic transmission - a disease transmitted from animals to people - of many disease pathogens is a significant concern worldwide. It is estimated that 60 of human emerging infectious diseases, including ... -
Development of novel polymeric delivery systems for the controlled release of therapeutic agents to prevent the spread of Zoonotic diseases
Silva Nunes Bezerra, Gilberto (Technological University of the Shannon: Midlands Midwest, 2023-07)The agricultural revolution and related activities have led to new connections between humans and farm animals, which are expected to expand due to the global trade of livestock and growth in the demand for animal protein ... -
The development of novel smart colour change polymer materials via various melt processing techniques
Breheny, Colette; Geever, Luke; Geever, Joseph (Athlone Institute of Technology, 2020-06)Smart polymers or stimuli-responsive polymers undergo large reversible changes, whether physical or chemical, in their properties as a consequence of small environmental variations. They can respond to a single stimulus ... -
Development of smart 4-D materials utilising novel self assembly polymers
Halligan, Elaine; Hayes, Conor; Geever, Luke (2020-06)4D printing is a technique that uses a 3 D printer to create objects that change their shape overtime 4 D printing involves the use of smart materials that will transform when exposed to an external stimuli These can ... -
The development of smart 4D materials using the smart temperature-sensitive polymer
Zhuo, Shuo; Geever, Luke; Geever, Joe; Keane, Gavin (TUS Midlands Midwest, 2022)There is more that can be done with a 3D structure to make them more flexible and more useful: by utilising structures (Smart Polymers) that can transform in a preprogrammed way in response to a stimulus. Thus, giving ... -
The development of smart 4D materials utilising smart temperature responsive polymers
Zhuo, Shuo (Technological University of the Shannon: Midlands Midwest, 2023)This study involved the preparation and optimisation of novel temperature-sensitive hydrogel copolymer and terpolymer systems, and also the development and evaluation of smart hydrogels with the potential for 4D printing ... -
Development of synthetic alternatives for bone tissue engineering.
Killion, John; Geever, Luke; Devine, Declan; Kennedy, James; Higginbotham, Clement L. (Australian Journal of Basic and Applied Sciences, 2013)Due to the inherent limitations of current biological bone grafts, alternative synthetic substitutes are being pursued. Therefore, this study aimed to improve the bioactive and compressive properties of photopolymerisable ... -
Effect of Chemical Treatments and HDPE-g-MA on the physical and mechanical behaviour of HDPE/ natural fibre composites.
Cao, Zhi; Peyregne, Marc; Daly, Michael; Mullen, Tom; Devine, Declan M.; Geever, Luke; Higginbotham, Clement L. (2013)Many authors have reported on the use of natural fibres (raw or chemically modified) as reinforcing elements for high density polyethylene (HDPE). These materials have generated a lot of interest due to their low cost ... -
Long-term release rate of a nutritional supplement from a biodegradable polymer matrix
Colbert, Declan; Geever, Joseph; Geever, Luke (Athlone Institute of Technology, 2020-06)For the purposes of ruminant nutrition, a 6-month timeframe is the ideal amount of time for the delivery of trace element and minerals. As a starting element, copper was chosen as it is the most commonly observed trace ... -
Novel technologies and optimised formulations for delivery of solid dispersion of BCS class II drugs
Hurley, Dean T. (Technological University of the Shannon: Midlands Midwest, 2023-06)The optimal design of amorphous solid dispersion (SD) formulations require the use of excipients to maintain supersaturation and improve physical stability in order to ensure shelf-life stability and better absorption ... -
The preparation of nanocomposite scaffolds for use in bone tissue engineering.
Hoctor, Eilish; Killion, John; Devine, Declan M.; Geever, Luke; Higginbotham, Clement L. (AJBAS, 2013)Bone is the second most frequently transplanted tissue in humans. There are 2.2 million bone graft procedures annually, which have several disadvantages such as: donor site morbidity, risk of disease transmission and a ... -
Processing and characterisation of various polymer blends to develop implant for tissue engineering applications.
Kenny, Elaine; Devine, Declan M.; Higginbotham, Clement L.; Geever, Luke (AESS, 2013)In the past two decades, the repair and reconstruction of musculoskeletal tissues using biodegradable scaffold materials has emerged as one of the most promising approaches in tissue engineering. The aim of this study ... -
Reinforced polylactic acid for use in high strength biodegradable medical implants.
Chen, Yuanyuan; Geever, Luke; Higginbotham, Clement L.; Killion, John; Lyons, John; Devine, Declan M. (2016)Traditional medical implants, such as orthopedic screws, pins, and coronary stents, are almost exclusively metallic due to high mechanical strength requirements. However, issues related to the use of permanent metallic ... -
Smart hydrogels: therapeutic advancements in hydrogel technology for smart drug delivery applications.
de Lima, Gabriel Goetten; Kanwar, Diwakar; Macken, Derek; Geever, Luke; Devine, Declan M.; Nugent, Michael J.D. (Wiley, 2015-12)Hydrogels are a fusion of solid and liquid phases which closely mimic biological tissue. As such they have enormous potential for drug delivery systems as they are biocompatible and may be tailored to specific applications. ... -
Smart thermosensitive poly (N-vinylcaprolactam) based hydrogels for biomedical applications.
Dalton, Maurice; Halligan, Shane; Killion, John; Murray, Kieran A.; Geever, Luke (AENSI, 2014-12-31)Photopolymerisation is an attractive technique used in biomedical applications as it can provide rapid reaction rates with excellent temporal and spatial control features and unique tuneable properties. This fabrication ... -
Synthesis and characterisation of novel temperature and pH sensitive physically crosslinked poly(N-vinylcaprolactam-co-itaconic acid) hydrogels for drug delivery.
Fallon, Megan; Halligan, Shane; Pezzoli, Romina; Geever, Luke; Higginbotham, Clement (MDPI, 2019-08-29)Previous studies involving poly N-vinylcaprolactam (PNVCL) and itaconic acid (IA) have synthesised the hydrogels with the presence of a solvent and a crosslinker, producing chemically crosslinked hydrogel systems. In this ... -
Synthesis of NVCL-NIPAM hydrogels using PEGMA as a chemical crosslinker for controlled swelling behaviours in potential shapeshifting applications
Tie, Bill Shu Hieng; Halligan, Elaine; Zhuo, Shuo; Keane, Gavin; Geever, Luke (MDPI, 2023-03-20)Stimuli-responsive hydrogels have recently gained interest within shapeshifting applications due to their capabilities to expand in water and their altering swelling properties when triggered by stimuli, such as pH and ...