Browsing Articles - Bioscience Research Institute (BRI) by Title
Now showing items 31-50 of 75
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Immunomodulatory activity of β-glucan polysaccharides isolated from different species of mushroom – A potential treatment for inflammatory lung conditions
(Elsevier, 2022-02-25)Acute respiratory distress syndrome (ARDS) is the most common form of acute severe hypoxemic respiratory failure in the critically ill with a hospital mortality of 40%. Alveolar inflammation is one of the hallmarks for ... -
Implications for the seafood industry, consumers and the environment arising from contamination of shellfish with pharmaceuticals, plastics and potentially toxic elements: a case study from Irish waters with a global orientation
(Elsevier, 2022-10-20)Shellfish are a rich source of minerals, B-vitamins and omega-3 to the human diet. The global population is expected to reach 9.6 billion people by 2050 where there will be increased demand for shellfish and for sustained ... -
In silico identification of potential PvFKBP35 inhibitors from Entadrophragma angolense Limonoids extracts as antimalarial agents
(Elsevier, 2023-08-05)Plasmodium species, which are spread by female Anopheles mosquitoes, are responsible for malaria. Out of the five major Plasmodium species, Plasmodium falciparum and Plasmodium vivax are the most deadly and invasive species ... -
An in vitro and in silico investigation of the antitrypanosomal activities of the stem bark extracts of Anopyxis klaineana (Pierre) Engl
(Cell Press, 2024-03-16)African Trypanosomiasis caused by trypanosome parasites continues to be a major neglected health problem, particularly in developing countries. Current treatments are marked by serious side effects, low effectiveness, ... -
In Vivo Imaging Sheds Light on the Susceptibility and Permissivity of Carassius auratus to Cyprinid Herpesvirus 2 According to Developmental Stage
(MDPI, 2023-08-15)Cyprinid herpesvirus 2 (CyHV-2) is a virus that causes mass mortality in economically important Carassius spp. However, there have been no comprehensive studies into host susceptibility or permissivity with respect to ... -
In vivo toxicity of bioreactor-grown biomass and exopolysaccharides from Malaysian tiger milk mushroom mycelium for potential future health applications
(Nature Research, 2021-11)Natural mycelial biomass (MB) and exopolysaccharides (EPS) of Malaysian tiger milk mushroom Lignosus rhinocerus are considered high-end components due to their high commercial potential value in drug discovery. This study ... -
In-vivo toxicity of bioreactor-grown biomass and exopolysaccharides from Malaysian Tiger milk mushroom mycelius for potential future health applications
(Nature Research, 2021-08-12)Natural mycelial biomass (MB) and exopolysaccharide (EPS) produced from bioreactor-grown Malaysian Tiger Milk Mushroom Lignosus rhinocerus are considered high-end components due to their high commercial potential value in ... -
Integrative genomics of the mammalian alveolar macrophage response to intraceullular mycobacteria
(BMC, 2021)Bovine TB (bTB), caused by infection with Mycobacterium bovis, is a major endemic disease affecting global cattle production. The key innate immune cell that first encounters the pathogen is the alveolar macrophage, ... -
Investigations on the use of exopolysaccharide derived from mycelial extract of Ganoderma lucidum as functional feed ingredient for aquaculture-farmed red hybrid Tilapia ( Oreochromis sp.)
(Elsevier, 2021-02-03)There is growing interest in medicinal fungi for promoting immunomodulation benefits in humans and animals. In this study, exopolysaccharide (EPS) from Ganoderma lucidum was used in feed (EFF) on production of farmed-red ... -
Mechanism of formation, characterization and cytotoxicity of green synthesized zinc nanoparticles obtained from Ilex paraguariensis leaves extract
(Elsevier, 2020-10)Zinc oxide nanoparticles (ZnONPs) was produced using Ilex paraguariensis (mate) leaves extract using a green synthesis process. The influence of ethanolic and aqueous plant extract and zinc source on the green synthesis ... -
Microalgae as a natural ecological bioindicator for the simple real-time monitoring of aquaculture wastewater quality including provision for assessing impact of extremes in climate variance - a comparative case study from the Republic of Ireland
(Elsevier, 2021-08-17)Aquaculture is one of the fastest growing food producing industries globally, providing ~50% of fish for human consumption. However, the rapid growth of aquaculture presents a range of challenges including balancing ... -
Microbiological characterisation and impact of suspended solids on pathogen removal from wastewaters in dairy processing factories.
(CUP, 2018-08)In this Research Communication we investigate the microbiological profile of 12 dairy wastewater streams from three contrasting Irish dairy processing factories to determine whether faecal indicators/pathogens were present ... -
Modification of hyaluronic acid to enable click chemistry photo-crosslinking of hydrogels with tailorable degradation profiles
(Elsevier, 2023-06-15)Hyaluronic acid (HA) is a naturally occurring mucopolysaccharide that, due to its inherent bioactivity and extracellular matrix-like structure, has the potential to be utilised extensively in tissue engineering. However, ... -
Mycotherapy: potential of fungal bioactives for the treatment of mental health disorders and morbidities of chronic pain
(MDPI, 2022-03-11)Mushrooms have been used as traditional medicine for millennia, fungi are the main natural source of psychedelic compounds. There is now increasing interest in using fungal active compounds such as psychedelics for alleviating ... -
Optimum conditions of roasting process of Liberica coffee towards the local and international preference
(Food Research, 2022-06)Coffea liberica is one of the common coffee species grown in most Southeast Asia countries, especially in Malaysia. However, its production accounts for just 2% globally. In general, coffee beans’ roasting temperature ... -
Packaging environmental impact on seafood supply chains: a review of life cycle assessment studies
(Wiley, 2022)Packaging is fundamental for food preservation and transportation but generates an environmental burden from its production and end-of-life management. This review evaluates packaging contribution to the environmental ... -
Pathogenic drug resistant fungi: a review of mitigation strategies
(MDPI, 2023-01-13)Fungal pathogens cause significant human morbidity and mortality globally, where there is a propensity to infect vulnerable people such as the immunocompromised ones. There is increasing evidence of resistance to antifungal ... -
Peatland-based innovation can potentially support and enable the sustainable development goals of the United Nations: case study from the Republic of Ireland.
(Elsevier, 2022-08-25)The aim of this case study is to develop a novel freshwater aquaculture organic-process in the Irish peatlands along with adjacent eco-innovation that will support food production and security regionally with a global ... -
Pellet diameter of ganoderma lucidum in a repeated-batch fermentation for the trio total production of biomass-exopolysaccharide-exopolysaccharid and its anti-oral cancer beta-glucan response
(AIMS, 2020-10-22)The pellet morphology and diameter range (DR) of Ganoderma lucidum were observed in a repeated-batch fermentation (RBF) for the trio total production of biomass, exopolysaccharide (EPS) and endopolysaccharide (ENS). Two ... -
Performance of Biomass and Exopolysaccharide Production from the Medicinal Mushroom Ganoderma lucidum in a New Fabricated Air-L-Shaped Bioreactor (ALSB)
(MDPI, 2023-02-22)Conventional stirred-tank bioreactor (STR) designs are optimised for cultures of bacteria but not fungal cultures; therefore, a new Air-L-Shaped Bioreactor (ALSB) was fabricated. The ALSB was designed to eliminate the wall ...