Now showing items 1-20 of 48

    • Oriented polymeric sheets exhibiting dichroism and articles containing the same. 

      Kumar, Anil; Foller, Peter C.; Park, David; Devine, Declan; Bastiaansen, C.W.M.; Tennissen, J.P.; Cloonan, Martin; Higginbotham, Clement L. (2007-12-20)
      Provided is an oriented polymeric sheet comprising a photochromic-dichroic material, wherein the sheet exhibits dichroism in an activated state. Also provided is a multilayer composite comprising at least a support layer ...
    • Smart hydrogels: therapeutic advancements in hydrogel technology for smart drug delivery applications. 

      de Lima, Gabriel Goetten; Kanwar, Diwakar; Macken, Derek; Geever, Luke; Devine, Declan M.; Nugent, Michael J.D. (Wiley, 2015-12)
      Hydrogels are a fusion of solid and liquid phases which closely mimic biological tissue. As such they have enormous potential for drug delivery systems as they are biocompatible and may be tailored to specific applications. ...
    • Electrospinning of hydrogels for biomedical applications 

      de Lima, Gabriel Goetten; Lyons, Sean; Devine, Declan M.; Nugent, Michael J.D. (Springer Nature, 2018)
      The field of biomedical applications for hydrogels requires the development of nanostructures with specific controlled diameter and mechanical properties. Nanofibers are ideally candidates for these advanced requirements, ...
    • Development of high strength nanocomposite for biodegradable stents 

      Venkatesh, Chaitra; Chen, Yuanyuan; Cao, Zhi; Brennan, Shane; Major, Ian; Lyons, John G.; Devine, Declan M. (Athlone Institute of Technology, 2018-04-24)
      The use of biodegradable polymer materials are considered to be good alternatives in urology (Donohue et. al. 2018), cardiovascular (Brie et. al. 2016) and tracheal airway stenosis which provide support before it is absorbed ...
    • 3D printed end of arm tooling (EOAT) of a robotic arm 

      Ong U Jing, Daniel; Lyons, Sean; Devine, Declan (Athlone Institute of Technology, 2018-04-24)
      This research furthers the practice of designing and manufacturing an EOAT for low weight applications by utilising additive manufacturing (“3D Printing”) techniques to decrease energy consumption via tool weight savings ...
    • The influence of mechanical stretching and freeze-thaw processing on the properties of polyvinyl alcohol hydrogels for drug delivery applications 

      Chee, Bor Shin; De Lima, Gabriel G.; Devine, Declan M.; Nugent, Michael J.D. (Athlone Institute of Technology, 2018-04-24)
      The study describes the development of physically cross-linked polyvinyl alcohol (PVA) hydrogels using uniaxial orientation via freeze-thawing (F/T). Although cryogels have shown significant improvements in long-term ...
    • Enhancing the bioavailability of hydrophobic drugs using hot melt extrusion 

      Devine, Declan M.; Higginbotham, Clement; Geever, Luke M.; Coffey, Conor (Athlone Institute of Technology, 2018-04-24)
      Many existing drugs (as well as new revelations) in the pharmaceutical industry bear a distinct disadvantage in the sense that they are not water soluble, displaying low bioavailability values and consequently a reduced ...
    • Degradable polymer nanocomposites for fused filament fabrication applications 

      Healy, Andrew V.; Geever, Luke M.; Devine, Declan M.; Lyons, John G. (Athlone Institute of Technology, 2018-04-24)
      The use of plastics in everyday life has increased dramatically during the course of the 20th and 21st century which is primarily due to the characteristics plastics offer in the development of new products to meet the ...
    • Structure response for cellulose-based hydrogels via characterization techniques. 

      de Sá, Marcelo Jorge Cavalcanti; de Lima, Gabriel Goetten; Segundo, Francisco Alipio de Sousa; Nugent, Michael J.D. (Springer, 2019)
      Hydrogels are three-dimensional crosslinked polymeric networks capable of imbibing substantial amounts of water or biological fluids and are widely used in biomedical applications, especially in pharmaceutical industry as ...
    • Development of electrospun PVA nanofibers via freeze-thawing method 

      Chee, Bor Shin; Wu, Husheng; Zhu, Wenquan; Masood, Unsa; Sampaio, Viviane Seba; Pereira, Bruno Leandro; Nugent, Michael J.D. (Athlone Institute of Technology, 2019)
      The polyvinyl alcohol (PVA) hydrogels are proven to have the benefits of improving water retention ability, cell attachment and controlled drug release in medical device materials for pharmaceutical applications. Due to ...
    • Electrospun hydrogels composites for bone tissue engineering. 

      Chee, Bor Shin; de Lima, Gabriel Goetten; Devine, Declan; Nugent, Michael J. D. (Woodhead Publishing, 2019)
      Electrospinning is one of the foremost nanotechnology applications to fabricate bone tissue engineering scaffolds with sizes in the nanometer range. It is regarded as a versatile, inexpensive, and relatively simple methodology ...
    • Polymer based additive manufacturing historical developments, process types and material considerations. 

      Pollack, Steven; Venkatesh, Chaitra; Neff, Martin; Hu, Guang; Fuenmayor, Evert; Lyons, John G.; Major, Ian; Devine, Declan M. (Springer Nature, 2019)
      3D printing is a manufacturing technique where parts are built in a layer-by-layer fashion. The earliest embodiments were based on generating successive layers of solidified materials at the air liquid interface through ...
    • Biodegradable medical implants 

      Chen, Yuanyuan; de Sá, Marcelo Jorge Cavalcanti; Dalton, Maurice; Devine, Declan M. (De Gruyter, 2019)
    • Titanium-niobium alloys covered by electrospinning technique to applications in bone implants 

      Pereira, Bruno Leandro; Chee, Bor Shin; Nugent, Michael J.D.; cao, Zhi (Athlone Institute of Technology, 2019)
      Recently, to avoid toxic metals in the human environment, there are many efforts to produce alloys containing titanium Ti and niobium Nb. Nb is a powerful stabilizer of beta-titanium phase[1]. Depending on the composition ...
    • Tailoring surface properties from nanotubes and anodic layers of titanium for biomedical applications. 

      de Lima, G.G.; da Luz, Aline Rossetto; Pereira, Bruno Leandro; Szez, Eduardo Mioduski; de Souza, Gelson Biscaia; Lepienski, Carlos Mauricio; Kuromoto, Neide Kazue; Nugent, Michael J.D. (Woodhead Publishing, 2019)
      The following chapter gives an overview of the anodic layers and nanotubes produced with plasma electrolytic oxidation. An introduction into the mechanisms involved in producing these nanofilms, such as the required ...
    • Electrospun natural polysaccharide for biomedical applications. 

      Chee, Bor Shin; Nugent, Michael (Elsevier, 2019-07-27)
      Electrospinning is a simple and versatile technique in nanotechnology for fabricating nanofibers scaffolds for tissue regenerations, drug delivery systems, wound healing, and cancer therapy. This chapter provides a synopsis ...
    • Orthopaedic 3D printing in orthopaedic medicine. 

      Brennan Fournet, Margaret; Azman, Farah Alwani Binti; Günbay, Suzan; Chen, Yuanyuan; Devine, Declan M. (Springer, 2019-09-17)
      Orthopaedic surgeries are commonly extremely challenging, and innovations are required to overcome a series of recognised difficulties and improve patient outcomes. Complications, in particular, the high occurrence of ...
    • Evaluation of the efficacy of lipid core nanoemulsions containing temozolomide coupled to ferrocenes in the treatment of Glioblastomas 

      Henn, Jeferson G.; Ferro, Matheus B.; Steffens, Luiza; da Rosa, Ricardo G.; Aguirre, Tanira A.S.; Nugent, Michael; Moura, Dinara J. (Athlone Institute of Technology, 2020)
      Glioblastoma (GB) is the most common and aggressive neoplastic brain tumor, and its treatment has proved to be a challenge. For decades its therapy has been based on the use of temozolomide (TMZ), but the survival rate ...
    • Preclinical assessment of biomimetic and bioactive bone regeneration scaffold in femoral condyle defect of Sprague Dawley rats. 

      Azaman, Farah Alwani; Brennan Fournet, Margaret (Athlone Institute of Technology, 2020)
      A fabricated biomimetic bone scaffold, incorporating osteogenic factors, presents a promising alternative to traditional autologous and allogeneic bone fracture treatments. Here, the principles of biology and engineering ...
    • Development of a versatile monitoring technique for real-time protein activity tracking within cellular environment and biomimetic tissue engineering scaffold systems 

      Rodriguez Barroso, L.; Lanzagorta Garcia, E.; Devine, D.M.; Lynch, M.; Huerta, M.; Fournet, M.B. (Athlone Institute of Technology, 2020-06)
      Crowded cellular environments with complex and intricate molecular interactions underpin biological processes. High biological noise is intrinsic within these biological systems, and this poses critical challenges to ...