Based on the benefits of Team-Based Learning (TBL) in higher education, our project investigated possible benefits of TBL in secondary education. We found that, despite challenges, the benefits of using TBL in secondary schools make it worth teachers’ time and effort. We conducted a year-long qualitative study with 13 teachers from Ireland, Spain and UK. While teachers found preparation time, institutional requirements, and managing student team dynamics challenging, challenges were outweighed by benefits including improved student engagement, quality of learning, skill development, and teacher job satisfaction. We recommend further TBL training for secondary-level teachers and further research into this topic.