PhD Theses
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The design, development, and testing of novel next generation in vitro agar-based urethral models for medical device innovation
(Technological University of the Shannon: Midlands Midwest, 2022-04)Catheters are one of the most utilised medical devices in modern medicine with catheter associated urinary tract infections (CAUTI) being ubiquitous in worldwide healthcare settings. These infections negatively affect ... -
Performance attenuation and recovery in Gaelic games
(Technological University of the Shannon: Midlands Midwest, 2022-07)Background: Gaelic games match-play involves players undertaking frequent and irregular anaerobic efforts interspersed with low-intensity aerobic activity, while being regularly exposed to physical contact during ... -
The effect of 60 days 6° head-down-tilt bed rest on the metabolic physiology of young, healthy males
(Technological University of the Shannon: Midlands Midwest, 2022-09)Introduction. Six-degree head-down-tilt (HDT) bed rest is a valuable experimental model for examining the physiological adaptations of gravity deprivation (spaceflight, physical inactivity, sedentary behaviour, ... -
The contribution of Gaelic football participation to physical activity in Irish youth
(Technological University of the Shannon: Midlands Midwest, 2022-03)Background: Physical activity (PA) provides a range of health benefits for adolescents. However, approximately 80% of adolescents internationally fail to meet the PA guidelines. Organised sport (OS) participation is ... -
Enhancing cyber attack prevention and detection using application process tracing
(Technological University of the Shannon: Midlands Midwest, 2022-08)Nowadays, software enterprises are being targeted by more advanced cyber-security threat models. Consequently, more sophisticated means of protecting software organisa tions are in high demand. Also, microservices are ... -
Interpretability and performance of deep neural network based anomaly detection in cyber security and telecommunications
(Technological University of the Shannon: Midlands Midwest, 2022-06)The rapid development of technology and proliferation of data have driven businesses to pursue anomaly detection research. The application of artificial neural networks (ANNs) in anomaly detection achieves the state-of-the-art, ... -
Enhancing drug solubility through advanced polymer extruded shellac-based matrix drug delivery systems
(Technological University of the Shannon: Midlands Midwest, 2022-09)The main objective of this study is to enhance the solubility of the model drug fenofibrate, by forming amorphous solid dispersions using a hot melt extrusion process. Hot melt extrusion offers an efficient way of ... -
A risk assessment-based control strategy to formulate a potent, efficacious, and non-invasive topical onychomycotic dosage form
(Technological University of the Shannon: Midlands Midwest, 2021)This project involves the development of a strategy to formulate a novel dosage form with modified coconut oil (MCO) as the active pharmaceutical ingredient to treat onychomycosis caused by T. rubrum and C. albicans. ... -
Development of next generation polymer based long-term controlled release devices for improved animal health
(Technological University of the Shannon: Midlands Midwest, 2021-12)While out to pasture, cattle are susceptible to developing trace mineral deficiencies due to insufficient mineral levels in forage. Due to this, cattle are commonly administered a trace element supplement in one of ... -
An investigation into the role of spatial ability in problem solving in engineering education
(Technological University of the Shannon: Midlands Midwest, 2021-11)Problem solving is a fundamental component of engineering practice and as such, the development of problem-solving skills is a core goal of engineering education. Problem-orientated pedagogical approaches are used in ... -
Critical studies on the novel development and implementation of Vaporized Hydrogen Peroxide (VH2O2) for terminal sterilization of medical devices encompassing use of flow cytometry for the real-time commensurate monitoring of microbial inactivation
(Technological University of the Shannon: Midlands Midwest, 2022-09)Aims and Rationale: Sterilization microbiology relies on determining the linearity of microbial survivor curves for calculating decimal reduction times (D-values) that is used to inform sterility assurance levels (SAL), ... -
Development of drug eluting biodegradable nanocomposite for use in coronary stents
(Athlone Institute of Technology, 2021-07)Coronary stents are the scaffolds placed inside the blocked arteries, which aids the restoration of the passage of blood to the heart. Coronary stenting has become a standard medical procedure to treat coronary heart disease ... -
The psychology of musculoskeletal injury in elite and sub-elite Gaelic footballers
(Athlone Institute of Technology, 2021-01)Background: Gaelic football participation is associated with an inherent risk of musculoskeletal injury eliciting physical and psychological consequences. However, there is a current dearth of awareness of the psychology ... -
An investigation of the in vitro effects of unconjugated linoleic acid and its potential impact on haemostasis
(Athlone Institute of Technology, 2021-04)Introduction: Linoleic acid, an essential ω6 fatty acid, is the most abundant polyunsaturated fatty acid in the Western mammalian diet. Linoleic acid has been linked with an increased inflammatory response. It has also ... -
Green synthesis of zinc oxide nanoparticles using Ilex paraguariensis leaves for application in antimicrobial polyelectrolyte biomaterials
(Athlone Institute of Technology, 2021)This research aims to develop and characterize antimicrobial polymer biomaterials containing zinc oxide nanoparticles (ZnONPs) obtained using Ilex paraguariensis (IP) leaf extract by green synthesis. The biomaterials ... -
Head- and eye-based features for continuous core affect prediction
(Athlone Institute of Technology, 2020-07)Feelings, or affect, are a fundamental part of human experience. Arousal and valencemake up core affect and have received intense study in affective computing. Speechand facial features have been extensively studied as ... -
Modification of PEGDMA hydrogels for use in the fabrication of peripheral nerve guidance conduits
(Athlone Institute of Technology, 2021-10)Peripheral nerve injury is a worldwide issue affecting millions. More than 719,000 people are receiving surgical treatment for peripheral nerve injury each year in the US alone. There is presently a market for the ... -
A quality of experience evaluation of augmented reality and haptic feedback in a low-cost gait analysis system
(Athlone Institute of Technology, 2020-06)Gait analysis is a technique that is used to understand movement patterns and, in some cases, to inform the development of rehabilitation protocols. Traditional rehabilitation approaches have relied on expert guided feedback ... -
The development of advanced smart polymer formulations for potential biomedical applications.
(Athlone Institute of Technology, 2020-10)In the past twenty years, a theme in the pharmaceutical industry is to move towards more efficient use of active pharmaceutical ingredients and the need for improved delivery systems. Smart polymers throughout the literature ... -
An investigation into critical factors influencing ecosystem dynamics in fish rearing water and disease mitigation eco-innovations for the enhancement of Irish freshwater aquaculture
(Athlone Institute of Technology, 2020)Aims and Rationale: The aquaculture sector is becoming the fastest growing food sector in the world, with an increasing requirement for higher production rates. With the maximum sustainable yield almost exhausted in terms ...
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