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Test purchase, synthesis and characterization of 3-fluorophenmetrazine (3-FPM) and differentiation from its ortho- and para-substituted isomers
(Wiley, 2017-03)
The knowledge captured in patent and scientific research literature stimulates
new ideas and fosters new drug development efforts. Manufacturers and
entrepreneurs dedicated to the sale of ‘research chemicals’ and/or ...
Synthesis, characterization and monoamine transporter activity of the new psychoactive substance 3’,4’-methylenedioxy-4-methylaminorex (MDMAR).
(Wiley, 2015-07)
The recent occurrence of deaths associated with the psychostimulant cis-4,4'-dimethylaminorex (4,4'-DMAR) in Europe indicated the presence of a newly emerged psychoactive substance on the market. Subsequently, the existence ...
Test purchase, synthesis and characterization of 2- methoxydiphenidine (MXP) and differentiation from its metaand para-substituted isomers.
(Wiley, 2015-09)
The structurally diverse nature of the 1,2-diphenylethylamine template provides
access to a range of substances for drug discovery work but some have attracted
attention as ‘research chemicals’. The most recent examples ...
Analytical characterization and pharmacological evaluation of the new psychoactive substance 4-fluoromethylphenidate (4F-MPH) and differentiation between the (±)-threo- and (±)-erythro- diastereomers
(Wiley, 2017-03)
Misuse of (±)-threo-methylphenidate (methyl-2-phenyl-2-(piperidin-2-yl)acetate; Ritalin®; MPH) has long been acknowledged, but the appearance of MPH analogs in the form of 'research chemicals' has only emerged in more ...
The synthesis and characterization of the ‘research chemical’ N-(1- amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl) -1H-pyrazole-5-carboxamide (3,5-AB-CHMFUPPYCA) and differentiation from its 5,3-regioisomer.
(Wiley, 2016-09)
This study presents the identification of N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-
(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide that was termed
3,5-AB-CHMFUPPYCA. This compound was obtained from a ...
Synthesis, analytical characterization and monoamine transporter activity of the new psychoactive substance 4- methylphenmetrazine (4-MPM), with differentiation from its ortho- and meta- positional isomers
(Wiley, 2018-09)
The availability of new psychoactive substances on the recreational drug
market continues to create challenges for scientists in the forensic, clinical
and toxicology fields. Phenmetrazine (3-methyl-2-phenylmorpholine) ...
Fluorinated phenmetrazine “legal highs” act as substrates for high-affinity monoamine transporters of the SLC6 family.
(Elsevier, 2018-05-15)
A variety of new psychoactive substances (NPS) are appearing in recreational drug markets worldwide.
NPS are compounds that target various receptors and transporters in the central nervous system to
achieve their ...