Browsing Department of Pharmaceutical Sciences and Biotechnology by Title
Now showing items 25-44 of 70
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In silico screening of phytochemicals from Dissotis rotundifolia against Plasmodium falciparum Dihydrofolate Reductase.
(Elsevier, 2023-04-01)Background: Malaria remains a major health concern in developing countries with high morbidity and mortality, especially in pregnant women and infants. A major obstacle to the treatment of malaria is a low effectiveness ... -
In vitro metabolism of the synthetic cannabinoid 3,5‐AB‐CHMFUPPYCA and its 5,3‐regioisomer and investigation of their thermal stability.
(Wiley, 2016-02)Recently, the pyrazole‐containing synthetic cannabinoid N‐(1‐amino‐3‐methyl‐1‐oxobutan‐2‐yl)‐1‐(cyclohexylmethyl)‐3‐(4‐fluorophenyl)‐1H‐pyrazole‐5‐carboxamide (3,5‐AB‐CHMFUPPYCA) has been identified as a ‘research chemical’ ... -
Influence of reconstitution temperature on survival of Cronobacter Sakazakii in powdered infant formula.
(Slovak University of Agriculture in Nitra. Faculty of Biotechnology and Food Sciences., 2016-04)Cronobacter spp. are emerging opportunistic pathogens commonly associated with the feeding of powdered infant formula (PIF). This study aimed to investigate the ability of C.sakazakii (ATCC 29544) to survive heat injury ... -
Insights into the mechanisms of Cronobacter sakazakii virulence
(Elsevier, 2022-06)Cronobacter species have adapted to survive harsh conditions, particularly in the food manufacture environment, and can cause life-threatening infections in susceptible hosts. These opportunistic pathogens employ a multitude ... -
An investigation into critical factors influencing ecosystem dynamics in fish rearing water and disease mitigation eco-innovations for the enhancement of Irish freshwater aquaculture
(Athlone Institute of Technology, 2020)Aims and Rationale: The aquaculture sector is becoming the fastest growing food sector in the world, with an increasing requirement for higher production rates. With the maximum sustainable yield almost exhausted in terms ... -
An investigation into the antibacterial and anti-inflammatory potential of an Irish Ivy Honey.
(Athlone Institute of Technology, 2018-02)A resurgence of interest into the medicinal uses of honey has occurred over recent years, with many investigations focusing on the healing properties of different monofloral honeys Amongst the most well known and well ... -
An investigation into the effectiveness of latent myofascial trigger point dry needling on muscle activation patterns.
(Athlone Institute of Technology, 2016-06)Background: Recent research on latent trigger points (LTrP) provides an opportunity to investigate the efficacy of trigger point (TrP) treatments without pain influencing results. One proposed negative outcome of LTrPs is ... -
Investigation into the novel application & utilisation of algae to aid in developing sustainable Irish freshwater aquaculture
(Athlone Institute of Technology, 2021-06)Aims and Rationale: Aquaculture is the fastest growing food producing industry in the world producing >50% of the world’s seafood. Food Wise 2025, an initiative set by the Irish government to develop the Irish Agri-Food ... -
The investigation of land management practices on the soil ecosystem
(AIT, 2019)Ireland has a cool-temperate climate and frequent rainfall which provides a suitable environment for rich, arable soil. Agriculture has always been a crucial part of Irish society, sustaining the country’s food stocks and ... -
Investigation of prolific sheep from UK and Ireland for evidence on origin of the mutations in BMP15 (FecXG, FecXB) and GDF9 (FecGH) in Belclare and Cambridge sheep.
(PLOS, 2013-01)This paper concerns the likely origin of three mutations with large effects on ovulation rate identified in the Belclare and Cambridge sheep breeds; two in the BMP15 gene (FecXG and FecXB) and the third (FecGH) in GDF9. ... -
An investigation of the in vitro effects of unconjugated linoleic acid and its potential impact on haemostasis
(Athlone Institute of Technology, 2021-04)Introduction: Linoleic acid, an essential ω6 fatty acid, is the most abundant polyunsaturated fatty acid in the Western mammalian diet. Linoleic acid has been linked with an increased inflammatory response. It has also ... -
Investigation of the potential variation of toxins in bog-land water system.
(AIT, 2017)Irish bogs have suffered much damage from human activities such as peat extraction or agricultural works. Peat extraction is normally carried out with the use of drainage ditches to cause drying for ease of extraction. ... -
Investigations on the efficacy of routinely used phenotypic methods compared to genotypic approaches for the identification of staphylococcal species isolated from companion animals in Irish veterinary hospitals
(BMC, 2013)BACKGROUND: Identification of Staphylococci to species level in veterinary microbiology is important to inform therapeutic intervention and management. We report on the efficacy of three routinely used commercial phenotypic ... -
Isocractic LC methods for the trace analysis of phthalates and 4-nonylphenol in varying types of landfill and adjacent run-offs.
(Taylor & Francis Online, 2007-07)To determine the levels of known endocrine disrupting chemicals such as phthalates and alkylphenols in environmental samples such as leachate water and sediment, suitable isocratic high performance liquid chromatographic ... -
Isosorbide-based cholinesterase inhibitors; replacement of 5-ester groups leading to increased stability.
(Elsevier, 2010-02-01)Isosorbide-2-carbamate-5-esters are highly potent and selective butyrylcholinesterase inhibitors with potential utility in the treatment of Alzheimer’s Disease (AD). They are stable in human plasma but in mouse plasma they ... -
A laboratory investigation of the antimicrobial activity of a selection of western phytomedicinal tinctures.
(Elsevier, 2018-04)Introduction: Following the observed success of a herbal cocktail in controlling and eliminating acute respiratory infections in a group of approximately sixty, 1–3 year old equines, it was decided to test ten of the herbs ... -
Laboratory methods with graphic support as a UDL strategy for science students in laboratory sessions.
(AHEAD, 2019-03)The National Access Plan (2015-2019) provides a framework for broadening participation in higher education -
Laccase oxidation studies: method development for following the benzyl alcohol oxidation reaction using the Laccase/TEMPO system
(Technological University of the Shannon Midlands Midwest, 2022)Biocatalysis is the use of nature’s biological catalysts – “enzymes” to perform synthetic chemical reactions, which are generally “greener” than traditional chemical methods. Laccases are a group of oxidoreductase enzymes ... -
The medicinal properties of Irish honey
(Technological University of the Shannon Midlands Midwest, 2022)Manuka honey is an internationally recognized honey licensed as a medicinal product for wounds1 . Medicinal honeys are often used in hospitals for partial thickness burns2 to surgical wounds and in veterinary clinics ... -
Microbiological degradation of pesticides in yard waste composting.
(American Society for Microbiology, 1991)Changes in public opinion and legislation have led to the general recognition that solid waste treatment practices must be changed. Solid-waste disposal by landfill is becoming increasingly expensive and regulated and no ...