Browsing Faculty of Science & Health: Midlands by Issue Date
Now showing items 21-40 of 314
-
Investigation of critical inter-related factors affecting the efficacy of pulsed light for inactivating clinically relevant bacterial pathogens
(Wiley, 2009-08)Aims: To investigate critical electrical and biological factors governing the efficacy of pulsed light (PL) for the in vitro inactivation of bacteria isolated from the clinical environment. Development of this alternative ... -
Studies on the susceptibility of different culture morphotypes of Listeria monocytogenes to uptake and survival in human polymorphonuclear leukocytes.
(Blackwell Publishing, 2009-09)This study demonstrated that atypical virulent filaments of Listeria monocytogenes (rough variant type II and designated FR for this study), isolated from clinical specimens or generated during exposure to pulsed-plasma ... -
Analysis of bio-obtainable endocrine disrupting metals in river water and sediment, sewage influent/effluent, sludge, leachate, and concentrated leachate, in the Irish Midlands Shannon catchment.
(Hindawi, 2009-12)The application of an acid digestion and subsequent solid-phase extraction (SPE) procedure were implemented as preliminary treatments prior to quantifying the levels of potentially endocrine disrupting metals (EDMs) in a ... -
Associations between the K232A polymorphism in the diacylglycerol-O-transferase 1 (DGAT1) gene and performance in Irish Holstein-Friesian dairy cattle
(Teagasc, 2010)Selection based on genetic polymorphisms requires accurate quantification of the effect or association of the polymorphisms with all traits of economic importance. The objective of this study was to estimate, using progeny ... -
Characterisation and toxicological evaluation of hydrogel-type polymeric biomatrials pre-and poststerilisation with a novel pulsed plasma gas-discharge system.
(Athlone Institute of Technology, 2010)This study investigated the in vitro biocompatibility and important physicochemical properties of unique N-vinyl-2-pyrrolidone–acrylic acid based copolymer hydrogels intended for use in biomedical applications. Moreover, ... -
Untreated and enzyme-modified bovine whey products reduce association of Salmonella typhinurim, Escherichia coli O157:H7 and Cronobactermalonaticus (formerly Enterobacter sakazakii) to CaCo-2 cells.
(Wiley, 2010-02)Aims: Adhesion of a micro-organism to a cell surface is often considered to be the first step in pathogenesis. Inhibiting this process may have therapeutic effects in vivo. This study investigates the inhibitory effects ... -
Isosorbide-based cholinesterase inhibitors; replacement of 5-ester groups leading to increased stability.
(Elsevier, 2010-02-01)Isosorbide-2-carbamate-5-esters are highly potent and selective butyrylcholinesterase inhibitors with potential utility in the treatment of Alzheimer’s Disease (AD). They are stable in human plasma but in mouse plasma they ... -
Emergence of Bacillus Cereus as a dominant organism in Irish retailed powdered infant formulae (PIF) when reconstituted and stored under abuse conditions
(Wiley, 2010-05-25)One hundred powdered infant formulae (PIF), representative of the 10 leading brands available in Ireland, were subjected to a variety of preparation and storage conditions. All PIF analyzed immediately after reconstitution were ... -
DNA sequence polymorphisms in a panel of eight candidate bovine imprinted genes and their association with performance traits in Irish Holstein-Friesian cattle.
(BMC, 2010-10-13)Background: Studies in mice and humans have shown that imprinted genes, whereby expression from one of the two parentally inherited alleles is attenuated or completely silenced, have a major effect on mammalian ... -
Defining established and emerging microbial risks in the aquatic environment: current knowledge, implications, and outlooks.
(Hindawi, 2011)This timely review primarily addresses important but presently undefined microbial risks to public health and to the natural environment. It specifically focuses on current knowledge, future outlooks and offers some potential ... -
DNA sequence polymorphisms within the bovine guanine nucleotide-binding protein Gs subunit alpha (Gsα)-encoding (GNAS) genomic imprinting domain are associated with performance traits
(BMC, 2011-01-11)Background: Genes which are epigenetically regulated via genomic imprinting can be potential targets for artificial selection during animal breeding. Indeed, imprinted loci have been shown to underlie some important ... -
Studies on the relationship between pulsed UV light irradiation and the simultaneous occurrence of molecular and cellular damage in clinically-relevant Candida albicans
(Elsevier, 2011-02)This constitutes the first study to report on the relationship between pulsed UV light (PL) irradiation and the simultaneous occurrence of molecular and cellular damage in clinical strains of Candida albicans. Microbial ... -
Irish staff nurses perceptions of clinical incident reporting
(Academic Journals, 2011-02)Clinical incident reporting identifies actual and potential risks to patient safety and then eliminates those risks through a system of procedural changes, policy enactment or changes in staff education. This constitutes ... -
Single nucleotide polymorphisms in the insulin-like growth factor 1 (IGF-1) gene are associated with performance in Holstein-Friesian dairy cattle.
(Frontiers, 2011-02-16)Insulin-like growth factor 1 (IGF-1) has been shown to be associated with fertility, growth, and development in cattle. The aim of this study was to (1) identify novel single nucleotide polymorphisms (SNPs) in the bovine ... -
Determination of the effect of dairy powders on adherence of Streptococcus sobrinus and Streptococcus salivarius to hydroxylapatite and growth of these bacteria
(Elsevier, 2011-06-12)Dental caries is a highly prevalent disease caused by colonisation of tooth surfaces by cariogenic bacteria, such as Streptococcus sobrinus and Streptococcus salivarius. Reducing initial adherence of such bacteria to teeth ... -
Single nucleotide polymorphisms in the growth hormone and insulin-like growth factor-1 genes are associated with milk production, body condition score and fertility traits in dairy cows.
(GMR, 2011-08-26)The somatotrophic axis (GH-IGF) is a key regulator of animal growth and development, affecting performance traits that include milk production, growth rate, body composition, and fertility. The aim of this study was to ... -
Polymorphism discovery and allele frequency estimation using high-throughput DNA sequencing of target-enriched pooled DNA samples
(BMC, 2012-01-11)Background: The central role of the somatotrophic axis in animal post-natal growth, development and fertility is well established. Therefore, the identification of genetic variants affecting quantitative traits within ... -
Investigations on the efficacy of routinely used phenotypic methods compared to genotypic approaches for the identification of staphylococcal species isolated from companion animals in Irish veterinary hospitals
(BMC, 2013)BACKGROUND: Identification of Staphylococci to species level in veterinary microbiology is important to inform therapeutic intervention and management. We report on the efficacy of three routinely used commercial phenotypic ... -
A review of the perceived barriers within the health belief model on PAP smear screening as a cervical cancer prevention measure.
(AESS, 2013)Aim: This study reviews the impact of perceived barriers on Pap cervical smear screening within the Health Belief Model (HBM) as an important prevention programme. Background: This research proposes to study perceived ...