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Mass-customization of oral tablets via the combination of 3D printing and injection molding.
(Elsevier, 2019-10-05)
The new frontier of medicine is the personalization of treatment to match a patient’s individual needs. Fused-filament fabrication (FFF) offers a platform for the personalization of drug dosage forms, but one of its chief ...
Development of high strength nanocomposite for biodegradable stents
(Athlone Institute of Technology, 2018-04-24)
The use of biodegradable polymer materials are considered to be good alternatives in urology (Donohue et. al. 2018), cardiovascular (Brie et. al. 2016) and tracheal airway stenosis which provide support before it is absorbed ...
The influence of mechanical stretching and freeze-thaw processing on the properties of polyvinyl alcohol hydrogels for drug delivery applications
(Athlone Institute of Technology, 2018-04-24)
The study describes the development of physically cross-linked polyvinyl alcohol (PVA) hydrogels using uniaxial orientation via freeze-thawing (F/T). Although cryogels have shown significant improvements in long-term ...
Analysis of the mechanical properties of solvent cast blends of PLA/PCL.
(Trans Tech Publications, 2014-09)
Polylactic acid (PLA) is the most promising material in the biodegradable category. However, brittleness and poor thermal stability restrict its application. To overcome this limitation, PLA may be blended with other ...
Enhancing the bioavailability of hydrophobic drugs using hot melt extrusion
(Athlone Institute of Technology, 2018-04-24)
Many existing drugs (as well as new revelations) in the pharmaceutical industry bear a distinct disadvantage in the sense that they are not water soluble, displaying low bioavailability values and consequently a reduced ...
Preparation and characterization of novel poly(vinyl) (alcohol) (PVA) and poly(acrylic acid) (PAA) hydrogels for sensitive hydrogels.
(Sciforum, 2014-05)
Stimuli Sensitive hydrogels have enormous potential in various applications. Various
environmental variables are found in the body, such as low pH and elevated temperatures. For this
reason, either pH-sensitive and/or ...
Electrospinning of hydrogels for biomedical applications
(Springer Nature, 2018)
The field of biomedical applications for hydrogels requires the development of nanostructures with specific controlled diameter and mechanical properties. Nanofibers are ideally candidates for these advanced requirements, ...
Orthopaedic 3D printing in orthopaedic medicine.
(Springer, 2019-09-17)
Orthopaedic surgeries are commonly extremely challenging, and innovations are required to overcome a series of recognised difficulties and improve patient outcomes. Complications, in particular, the high occurrence of ...
Degradable polymer nanocomposites for fused filament fabrication applications
(Athlone Institute of Technology, 2018-04-24)
The use of plastics in everyday life has increased dramatically during the course of the 20th and 21st century which is primarily due to the characteristics plastics offer in the development of new products to meet the ...
Comparison of fused-filament fabrication to direct compression and injection molding in the manufacture of oral tablets.
(Elsevier, 2019-03-10)
Oral tablets are a convenient form to deliver active pharmaceutical ingredients (API) and have a high level of acceptance from clinicians and patients. There is a wide range of excipients available for the fabrication of ...