Show simple item record

dc.contributor.authorMcHugo, Gillian
dc.contributor.authorBrowett, Sam
dc.contributor.authorRandhawa, Imtiaz A. S.
dc.contributor.authorHoward, Dawn
dc.contributor.authorMullen, Michael P.
dc.contributor.authorRichardson, Ian W.
dc.contributor.authorPark, Stephen D. E.
dc.contributor.authorMagee, David A.
dc.contributor.authorScraggs, Erik
dc.contributor.authorDover, Michael J.
dc.contributor.authorCorreia, Carolina N.
dc.contributor.authorHanrahan, James P.
dc.contributor.authorMacHugh, David E.
dc.identifier.citationMcHugo. G. P., Browett, S., Randhawa, I.A.S., Howard, D.J., Mullen, M.P., Richardson, I.W., Park, S.D.E., Magee, D.A., Scraggs, E., Dover, M.J., Correia, C. N., Hanrahan, J.P., MacHugh, D.E. (2019). A population genomics analysis of the native Irish Galway sheep breed. Frontiers in Genetics. 10:927. doi: 10.3389/fgene.2019.00927en_US
dc.identifier.otherArticles - Faculty of Science & Health AITen_US
dc.description.abstractThe Galway sheep population is the only native Irish sheep breed and this livestock genetic resource is currently categorised as ‘at-risk’. In the present study, comparative population genomics analyses of Galway sheep and other sheep populations of European origin were used to investigate the microevolution and recent genetic history of the breed. These analyses support the hypothesis that British Leicester sheep were used in the formation of the Galway. When compared to conventional and endangered breeds, the Galway breed was intermediate in effective population size, genomic inbreeding and runs of homozygosity. This indicates that, although the Galway breed is declining, it is still relatively genetically diverse and that conservation and management plans informed by genomic information may aid its recovery. The Galway breed also exhibited distinct genomic signatures of artificial or natural selection when compared to other breeds, which highlighted candidate genes that may be involved in production and health traitsen_US
dc.publisherFrontiers Mediaen_US
dc.relation.ispartofFrontiers in Geneticsen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Ireland*
dc.subjectAt-risk breeden_US
dc.subjectConservation genomicsen_US
dc.subjectGenetic diversityen_US
dc.subjectSelection signatureen_US
dc.subjectSingle nucleotide polymorphismen_US
dc.titleA population genomics analysis of the native Irish Galway sheep breed.en_US
dc.contributor.sponsorDepartment of Agriculture, Food and the Marine (DAFM) funding under the Genetic Resources for Food and Agriculture scheme (grant no: 09/GR/06); an Investigator Programme Grant from Science Foundation Ireland (SFI/08/IN.1/B2038); a Research Stimulus Grant from DAFM (RSF 06 406); a European Union Framework 7 Project Grant (KBBE-211602-MACROSYS); the Brazilian Science Without Borders Programme (CAPES grant no. BEX-13070en_US
dc.identifier.doidoi: 10.3389/fgene.2019.00927
dc.rights.accessOpen Accessen_US
dc.subject.departmentFaculty of Science & Health AITen_US

Files in this item


This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivs 3.0 Ireland
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Ireland