Show simple item record

dc.contributor.authorAzaman, Farah Alwani
dc.contributor.authorBrennan Fournet, Margaret
dc.identifier.citationAzaman, F.A., Brennan Fournet, M., Devine, D.M. (2020). Preclinical assessment of biomimetic and bioactive bone regeneration scaffold in femoral condyle defect of Sprague Dawley rats. [Poster]. Athlone: AIT Research.en_US
dc.identifier.otherOther - Materials Research Institute AITen_US
dc.description.abstractA fabricated biomimetic bone scaffold, incorporating osteogenic factors, presents a promising alternative to traditional autologous and allogeneic bone fracture treatments. Here, the principles of biology and engineering are combined in the development of viable tissue regeneration scaffolds designed to restore and maintain the function of human (bone) tissue. Our aim is to produce a cost effective bone healing biodegradable scaffold that overcomes current technology limitations and provides better safety than current mainstay market products. To date, the initial development phase of this project has been completed and in vitro studies have been performed providing positive outcomes. A preclinical assessment, where the scaffolds was implanted in Sprague Dawley rat defective femoral condyles has been carried out to investigate the efficiency of the scaffold in promoting bone healing. Histological analysis of the osteogenic and bioactive properties of the scaffolds has been conducted validating the efficacy of controlled low dose growth factor release compared with equivalent commercially available bone healing productsen_US
dc.publisherAthlone Institute of Technologyen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Ireland*
dc.subjectBone regenerationen_US
dc.subjectPreclinical assessmenten_US
dc.titlePreclinical assessment of biomimetic and bioactive bone regeneration scaffold in femoral condyle defect of Sprague Dawley rats.en_US
dc.rights.accessOpen Accessen_US
dc.subject.departmentMaterials Research Institute - AITen_US

Files in this item


This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivs 3.0 Ireland
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Ireland