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dc.contributor.authorRyan, Lisa
dc.contributor.authorClarke, Rachel
dc.description.abstractElevated dietary intake of processed, high glycaemic index (GI) carbohydrates is associated with an increased risk of developingchronic diseases such as type 2 diabetes, cardiovascular disease, obesity and cancer(1,2). The postprandial glycaemic response (GR)to carbohydrate-rich foods is determined by several factors including the digestibly of the starch,fibre content, and processing tech-niques(3). The addition of fat to a high GI food, such as white bread, is known to lower the postprandial GR(4). The effect offat typeon postprandial response however is not clear. The purpose of this study was to determine whether a difference exists in the glycaemicand satiety responses to white bread meals following the addition of a saturated fat-rich source (butter), monounsaturated fat-richsource (olive oil), or polyunsaturated fat-rich source (sunflower oil) in healthy females.In a three-way cross over design, female subjects (n = 9) were randomised to the order in which they received the three test meals,each providing 50 g available carbohydrate. Blood glucose concentration and subjective satiety ratings were collected and used to de-termine the 2-hour blood glucose response and 3-hour satiety response to each meal. In addition, the glycaemic profile, a measure ofpostprandial blood glucose trajectory, was calculated.There was no significant difference (P > 0·05) between total incremental area under the GR curve (iAUC) following each test meal(113·0±9·6, 150·2±24·6, 126·3±16·9 for butter, olive oil and sunflower oil meals respectively) using repeated measures ANOVA.After analysing the segmental iAUC for each meal it was found that olive oil induced a significantly higher GR than the other test fatsources for both 0–90 minute and 0–120 minute segments (P = 0·002 for both 0–90 and 0–120 minutes compared to butter, and P =0·022 for both 0–90 and 0–120 minutes compared to sunflower oil). There was no significant difference observed between the glycaem-ic profile in response to each meal (92·0±3·3, 78·7±8·9, 98·7±10·2 min/mmol/L, P = 0·188 for butter, olive oil and sunflower oil re-spectively). Analysis of Visual Analogue Scales (VAS) highlighted that there were no significant differences (P > 0·05) for subjectiveratings of hunger and fullness between the different meal conditions.In conclusion thesefindings suggest that there is no benefit in using unsaturated fats over saturated fats in lowering the glycaemicresponse or increasing postprandial satiety to a high GI food in healthy women.en_US
dc.publisherProceedings of The Nutrition Societyen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Ireland*
dc.subjectType 2 diabetesen_US
dc.subjectHigh glycaemic index (GI) carbohydratesen_US
dc.subjectPostprandial satietyen_US
dc.titleFat saturation has no effect on glycaemic or satiety response to a high GI carbohydrate meal in healthy womenen_US
dc.rights.accessOpen Acessen_US
dc.subject.departmentSchool of Scienceen_US

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Attribution-NonCommercial-NoDerivs 3.0 Ireland
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