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Now showing items 11-20 of 31
Material considerations for fused-filament fabrication of solid dosage forms.
(MDPI, 2018-04-02)
Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, ...
Characteristics of the treated calcium carbonate particles with stearic acid using different treating methods.
(Elsevier, 2016-08)
Calcium carbonate (CaCO3) is often treated with stearic acid (SA) to decrease its polarity. However, the method of application of the SA treatments has a strong influence on their interface structure and distribution. ...
Process optimization for the 3D printing of PLA and HNT composites with Arburg plastic freeforming
(MDPI, 2022-10-12)
The industrial use of additive manufacturing continues to rapidly increase as new technology
developments become available. The Arburg plastic freeforming (APF) process is designed to
utilize standard polymeric granules ...
On the possibility of replacement of calcium carbonate by a high-performance, economically viable filler in polyethylene composites
(Sage, 2021-07-14)
Calcium carbonate (CaCO3) is frequently added to polyethylene (PE) as a filler to reduce costs. An alternative to CaCO3, calcium fluoride (CaF2) was proposed in this research. PE/CaCO3 and PE/CaF2 composites in a wide ...
A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix
(MDPI, 2020-12-06)
This study was performed to develop an adjuvant therapy in the form of a self-administered
vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to
reduce relapse by eradicating ...
Hyaluronic acid: a review of the drug delivery capabilities of this naturally occurring polysaccharide
(MDPI, 2022-08-23)
The inclusion of physiologically active molecules into a naturally occurring polymer matrix can improve the degradation, absorption, and release profile of the drug, thus boosting the therapeutic impact and potentially ...
Purified β‐glucans from the Shiitake mushroom ameliorates antibiotic‐resistant Klebsiella pneumoniae‐induced pulmonary sepsis
(Society for Applied Microbiology, 2020-07-24)
Bacterial infection remains the main cause of acute respiratory distress syndrome and is a leading cause of death and disability in critically ill patients. Here we report on the use of purified β‐glucan (lentinan) extracts ...
Vaginal drug delivery for the localised treatment of cervical cancer.
(Springer, 2017-06-08)
Cervical cancer is usually treated by surgery, with
the more advanced cancers requiring adjuvant chemotherapy
or radiotherapy. The location of the cervix makes it easily
accessible through the vagina for the localised ...
Additive manufacturing of PLA/HNT nanocomposites for biomedical applications
(Elsevier, 2019)
Additive manufacturing has been of great interest of research in various applications due to their ease in processability, cost effectiveness and adaptability. In this study Poly Lactic Acid (PLA) was used as the base ...
Matrix and reservoir-type multipurpose vaginal rings for controlled release of dapivirine and levonorgestrel
(Elsevier, 2016-09-10)
A matrix-type silicone elastomer vaginal ring providing 28-day continuous release of dapivirine (DPV) a lead candidate human immunodeficiency virus type 1 (HIV-1) microbicide compound has recently demonstrated moderate ...