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Now showing items 1-10 of 27
Mass-customization of oral tablets via the combination of 3D printing and injection molding.
(Elsevier, 2019-10-05)
The new frontier of medicine is the personalization of treatment to match a patient’s individual needs. Fused-filament fabrication (FFF) offers a platform for the personalization of drug dosage forms, but one of its chief ...
Influence of annealing and biaxial expansion on the properties of Poly-l-lactic) medical tubing.
(MDPI, 2019-07-11)
Poly-l-lactic acid (PLLA) is one of the most common bioabsorbable materials in the medical
device field. However, its use in load-bearing applications is limited due to its inferior mechanical
properties when compared ...
Pathogen displacement during intermittent catheter insertion: a novel in vitro urethra model.
(Wiley, 2019-11-29)
Aim: To develop a novel in vitro urethra model and use it to determine if insertion of an intermittent urinary catheter (IC) displaces pathogenic bacteria from the urethral meatus along the urethra. Methods: Displacement ...
A tough and novel dual-response PAA/P(NiPAAM-co-PEGDMA) IPN hydrogels with ceramics by photopolymerization for consolidation of bone fragments following fracture.
(IOP Science, 2019-07)
In this work, a novel dual-response hydrogel for enhanced bone repair following multiple fractures was investigated. The conventional treatment of multiple bone fracture consists on removing smaller bone fragments from the ...
Enhancement of mechanical properties and wettability of TiO2NT arrays formed in simulated body fluid‐based electrolyte.
(Wiley, 2019-09-13)
Modified titanium nanotubes (TiO2NTs) coatings are grown in simulated body fluid (SBF) from Ticp and Ti6Al4V. The addition of 1% v/v of SBF to the electrolyte neither modifies film morphology nor the structural oxide ...
Micro-injection moulding of poly(vinylpyrrolidone-vinyl acetate) binary and ternary amorphous solid dispersions.
(MDPI, 2019-05)
Micro-injection moulding (µIM) was used for the production of enteric tablets of plasticised
and unplasticised solid dispersions of poly(vinylpyrrolidone-vinyl acetate) (PVPVA), and the effect
of the mechanical and thermal ...
Optimizing the hardness of SLA printed objects by using the neural netwok and genetic algorithm
(Elsevier, 2019-06)
In the developing field of manufacturing, 3D printing is rapidly increasing the horizon of what is possible. However, the possibility of implementing new 3D methods of production has brought new challenges for industries, ...
Preparation of biodegradable poltyethylene glycol dimethacrylate hydrogels via thiol-ene chemistry.
(MDPI, 2019-08-13)
Through the control of the molecular weight, water content and monomer concentration, polyethylene glycol dimethacrylate (PEGDMA) based hydrogels have been adapted for numerous applications, including as structural scaffolds, ...
Stability studies of hot-melt extruded ternary solid dispersions of poorly-water soluble Indomethacin with Poly(vinyl pyrrolidone-co-vinyl acetate) and polyethylene oxide.
(Elsevier, 2019-08)
This investigation aims to evaluate the effect of moisture and temperature on the physical
stability and dissolution behaviour of hot-melt extruded binary and plasticised ternary solid
dispersions. Poorly water-soluble ...
Faster release of lumen-loaded drugs than matrix-loaded equivalent in polylactic acid/halloysite nanotubes.
(MDPI, 2019-06-15)
Nanocomposite-based drug delivery systems with intrinsic controlled release properties are of great interest in biomedical applications. We report a novel polylactic acid (PLA)/halloysite nanotube (HNT) nanocomposite-based ...