Browsing Articles - Materials Research Institute AIT by Author "Pezzoli, Romina"
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3D printed polymers are less stable than injection moulded counterparts when exposed to terminal sterilization processes using novel vaporized hydrogen peroxide and electron beam processes.
Chen, Yuanyuan; Neff, Martin; McEvoy, Brian; Cao, Zhi; Pezzoli, Romina; Murphy, Alan; Gately, Noel; Hopkins Jnr, Michael; Rowan, Neil J.; Devine, Declan M. (Elsevier, 2019-11-21)There is an increasing trend for use of 3D printing processes in healthcare due in part to emergence of customised medical devices and associated low manufacturing cost. However, there is a dearth of knowledge on the ... -
Investigation of miscibility estimation methods between indomethacin and poly(vinylpyrrolidone-co-vinyl acetate).
Pezzoli, Romina; Lyons, John G.; Gatley, Noel; Higginbotham, Clement L. (Elsevier, 2018)The investigation of the miscibility between active pharmaceutical ingredients (API’s) and polymeric excipients is of great interest for the formulation and development of amorphous solid dispersions, especially in the ... -
Micro-injection moulding of poly(vinylpyrrolidone-vinyl acetate) binary and ternary amorphous solid dispersions.
Pezzoli, Romina; Hopkins, Michael Jnr.; Direur, Guillaume; Gatley, Noel; Lyons, John G.; Higginbotham, Clement L. (MDPI, 2019-05)Micro-injection moulding (µIM) was used for the production of enteric tablets of plasticised and unplasticised solid dispersions of poly(vinylpyrrolidone-vinyl acetate) (PVPVA), and the effect of the mechanical and thermal ... -
Stability studies of hot-melt extruded ternary solid dispersions of poorly-water soluble Indomethacin with Poly(vinyl pyrrolidone-co-vinyl acetate) and polyethylene oxide.
Pezzoli, Romina; Lyons, John G.; Gatley, Noel; Higginbotham, Clement L. (Elsevier, 2019-08)This investigation aims to evaluate the effect of moisture and temperature on the physical stability and dissolution behaviour of hot-melt extruded binary and plasticised ternary solid dispersions. Poorly water-soluble ... -
Synthesis and characterisation of novel temperature and pH sensitive physically crosslinked poly(N-vinylcaprolactam-co-itaconic acid) hydrogels for drug delivery.
Fallon, Megan; Halligan, Shane; Pezzoli, Romina; Geever, Luke; Higginbotham, Clement (MDPI, 2019-08-29)Previous studies involving poly N-vinylcaprolactam (PNVCL) and itaconic acid (IA) have synthesised the hydrogels with the presence of a solvent and a crosslinker, producing chemically crosslinked hydrogel systems. In this ...