Browsing Articles - PRISM: Polymer, Recycling, Industrial, Sustainability and Manufacturing Institute by Author "Lyons, John G."
Now showing items 1-20 of 23
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3D printed end of arm tooling (EOAT) for robotic automation.
Jing, Daniel Ong U.; Devine, Declan M.; Lyons, John G. (MDPI, 2018-09)This research furthers the practice of designing and manufacturing End of Arm Tooling (EOAT) by utilizing a low cost additive manufacturing Fused Filament Fabrication (FFF) technique to enable tool weight saving and ... -
Additive manufacturing of personalized pharmaceutical dosage forms via stereolithography.
Healy, Andrew V.; Fuenmayor, Evert; Doran, Patrick; Geever, Luke M.; Higginbotham, Clement L.; Lyons, John G. (MDPI, 2019-12-03)The introduction of three-dimensional printing (3DP) has created exciting possibilities for the fabrication of dosage forms, paving the way for personalized medicine. In this study, oral dosage forms of two drug ... -
Comparison of fused-filament fabrication to direct compression and injection molding in the manufacture of oral tablets.
Fuenmayor, Evert; Forde, Martin; Healy, Andrew V.; Devine, Declan M.; Lyons, John G.; McConville, Christopher; Major, Ian (Elsevier, 2019-03-10)Oral tablets are a convenient form to deliver active pharmaceutical ingredients (API) and have a high level of acceptance from clinicians and patients. There is a wide range of excipients available for the fabrication of ... -
Degradable nanocomposites for fused filament fabrication applications.
Healy, Andrew V.; Waldron, Cathal; Geever, Luke M.; Devine, Declan M.; Lyons, John G. (MDPI, 2018-05-09)There has been a substantial increase in the use and development of plastics over the last century. However, due to ever-diminishing petroleum feedstocks and growing concern for the environment, there has been a rise in ... -
The effect of cooling on the degree of crystallinity, solid-state properties, and dissolution rate of multi-component hot-melt extruded solid dispersions.
Hurley, Dean; Davis, Mark; Walker, Gavin M.; Lyons, John G.; Higginbotham, Clement L. (MDPI, 2020-03-01)The effect of cooling on the degree of crystallinity, solid-state and dissolution properties of multi-component hot-melt extruded solid dispersions [SD] is of great interest for the successful formulation of amorphous ... -
Faster release of lumen-loaded drugs than matrix-loaded equivalent in polylactic acid/halloysite nanotubes.
Venkatesh, Chaitra; Clear, Oran; Lyons, John G.; Devine, Declan M.; Faster release of lumen (MDPI, 2019-06-15)Nanocomposite-based drug delivery systems with intrinsic controlled release properties are of great interest in biomedical applications. We report a novel polylactic acid (PLA)/halloysite nanotube (HNT) nanocomposite-based ... -
Fused-filament fabrication of PEEK: a review of process-structure-property relationships.
Zanjanijam, Ali Reza; Major, Ian; Lyons, John G.; Lafont, Ugo; Devine, Declan M. (MDPI, 2020-07-27)Poly (ether ether ketone) (PEEK) is a high-performance engineering thermoplastic polymer with potential for use in a variety of metal replacement applications due to its high strength to weight ratio. This combination ... -
Halloysite nanotube reinforced polylactic acid composite.
Chen, Yuanyuan; Geever, Luke M.; Killion, John; Lyons, John G.; Higginbotham, Clement L. (Wiley, 2017-10)Polylactic acid (PLA) has long history in medical applications, and reinforced PLA has the potential to be used in the medical applications that require high mechanical strength such as coronary stents and bone fixation ... -
Heat dissipation plays critical role for longevity of polymer-based 3D-printed inserts for plastics injection moulding.
Moritz, Vicente; Bezerra, Gilberto S.N.; Hopkins, Michael Jnr.; Fuenmayor, Evert; Günbay, Suzan; Hayes, Conor; Lyons, John G.; Devine, Declan M. (MDPI, 2022-10-08)Injection moulding is a polymer processing method of choice for making plastic parts on industrial scale, but its traditional mould is made from tooling steel with time-consuming and costly production. Additive manufacturing ... -
Influence of annealing and biaxial expansion on the properties of Poly-l-lactic) medical tubing.
Dillon, Brian; Doran, Patrick; Fuenmayor, Evert; Healy, Andrew V.; Gately, Noel M.; Major, Ian; Lyons, John G. (MDPI, 2019-07-11)Poly-l-lactic acid (PLLA) is one of the most common bioabsorbable materials in the medical device field. However, its use in load-bearing applications is limited due to its inferior mechanical properties when compared ... -
Influence of extrusion screw speed on the properties of halloysite nanotube impregnated polylactic acid nanocomposites
Venkatesh, Chaitra; Chen, Yuanyuan; Cao, Zhi; Brennan, Shnae; Major, Ian; Lyons, John G.; Devine, Declan M. (De Gruyter, 2021)Poly (lactic acid)/halloysite nanotube (PLA/HNT) nanocomposites have been studiedextensively over the past fewyears owing to the interesting properties of the polymer, PLA, and the nanoclay, HNT, individually and as ... -
The influence of low shear microbore extrusion on the properties of high molecular weight poly(l-lactic acid) for medical tubing applications.
Dillon, Brian; Doran, Patrick; Fuenmayor, Evert; Healy, Andrew V.; Gately, Noel M.; Major, Ian; Lyons, John G. (MDPI, 2019-04)Biodegradable polymers play a crucial role in the medical device field, with a broad range of applications such as suturing, drug delivery, tissue engineering, sca olding, orthopaedics, and fixation devices. Poly-l-lactic ... -
Investigation of miscibility estimation methods between indomethacin and poly(vinylpyrrolidone-co-vinyl acetate).
Pezzoli, Romina; Lyons, John G.; Gatley, Noel; Higginbotham, Clement L. (Elsevier, 2018)The investigation of the miscibility between active pharmaceutical ingredients (API’s) and polymeric excipients is of great interest for the formulation and development of amorphous solid dispersions, especially in the ... -
An investigation of the inter-molecular interaction, solid-state properties and dissolution properties of mixed Copovidone hot-melt extruded solid dispersions.
Hurley, Dean; Carter, David; Ng, Lawrence Yee Foong; Davis, Mark; Walker, Gavin M.; Lyons, John G.; Higginbotham, Clement L. (Elsevier, 2019-10)Previous research has focused on spray dried quaternary mixtures which due to the addition of a surfactant 26 affected the physical stability and amorphous stability of selected model drugs. Very little research has 27 ... -
Mass-customization of oral tablets via the combination of 3D printing and injection molding.
Fuenmayor, Evert; O'Donnell, Crevan; Gately, Noel; Doran, Patrick; Devine, Declan M.; Lyons, John G.; McConville, Christopher; Major, Ian (Elsevier, 2019-10-05)The new frontier of medicine is the personalization of treatment to match a patient’s individual needs. Fused-filament fabrication (FFF) offers a platform for the personalization of drug dosage forms, but one of its chief ... -
Material considerations for fused-filament fabrication of solid dosage forms.
Fuenmayor, Evert; Forde, Martin; Healy, Andrew V.; Devine, Declan M.; Lyons, John G.; McConville, Christopher; Major, Ian (MDPI, 2018-04)Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, ... -
Material considerations for fused-filament fabrication of solid dosage forms.
Fuenmayor, Evert; Forde, Martin; Healy, Andrew M.; Devine, Declan M.; Lyons, John G.; McConville, Christopher; Major, Ian (MDPI, 2018-04-02)Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, ... -
Micro-injection moulding of poly(vinylpyrrolidone-vinyl acetate) binary and ternary amorphous solid dispersions.
Pezzoli, Romina; Hopkins, Michael Jnr.; Direur, Guillaume; Gatley, Noel; Lyons, John G.; Higginbotham, Clement L. (MDPI, 2019-05)Micro-injection moulding (µIM) was used for the production of enteric tablets of plasticised and unplasticised solid dispersions of poly(vinylpyrrolidone-vinyl acetate) (PVPVA), and the effect of the mechanical and thermal ... -
Nanofillers can be used to enhance the thermal conductivity of commercially available SLA resins.
Hu, Guang; Cao, Zhi; Hopkins, Michael; Lyons, John G.; Brennan-Fournet, Margaret; Devine, Declan M. (Elsevier, 2019-06)Stereolithography (SLA) is a form of 3D printing technology used for the production parts and patterns in a layer by layer fashion. Traditionally, 3D printing has been used for the manufacture of prototypes, however it is ... -
Review of multifarious applications of Poly (lactic acid)
Chen, Yuanyuan; Geever, Luke M.; Killion, John A.; Lyons, John G.; Higginbotham, Clement L. (Taylor & Francis, 2016)Poly (lactic acid) is considered to be a promising alternative to petroleum-based polymers due to its renewability, biodegradability, biocompatibility, and good mechanical properties. Because of the high cost, the applications ...