Now showing items 1-16 of 16

    • Additive manufacturing of personalized pharmaceutical dosage forms via stereolithography. 

      Healy, Andrew V.; Fuenmayor, Evert; Doran, Patrick; Geever, Luke M.; Higginbotham, Clement L.; Lyons, John G. (MDPI, 2019-12-03)
      The introduction of three-dimensional printing (3DP) has created exciting possibilities for the fabrication of dosage forms, paving the way for personalized medicine. In this study, oral dosage forms of two drug ...
    • Additive manufacturing of PLA/HNT nanocomposites for biomedical applications 

      Venkatesh, Chaitra; Fuenmayor, Evert; Doran, Patrick; Major, Ian (Elsevier, 2019)
      Additive manufacturing has been of great interest of research in various applications due to their ease in processability, cost effectiveness and adaptability. In this study Poly Lactic Acid (PLA) was used as the base ...
    • Applications of Digital Twin across industries: a review 

      Singh, Maulshree; Srivastava, Rupal; Fuenmayor, Evert; Kuts, Vladimir; Qiao, Yuansong; Murray, Niall; Devine, Declan (MDPI, 2022-06-14)
      One of the most promising technologies that is driving digitalization in several industries is Digital Twin (DT). DT refers to the digital replica or model of any physical object (physical twin). What differentiates DT ...
    • Comparison of fused-filament fabrication to direct compression and injection molding in the manufacture of oral tablets. 

      Fuenmayor, Evert; Forde, Martin; Healy, Andrew V.; Devine, Declan M.; Lyons, John G.; McConville, Christopher; Major, Ian (Elsevier, 2019-03-10)
      Oral tablets are a convenient form to deliver active pharmaceutical ingredients (API) and have a high level of acceptance from clinicians and patients. There is a wide range of excipients available for the fabrication of ...
    • Digital twin: origin to future 

      Singh, Maulshree; Fuenmayor, Evert; Hinchy, Eoin P.; Qiao, Yuansong; Murray, Niall (MDPI, 2021-05-24)
      Digital Twin (DT) refers to the virtual copy or model of any physical entity (physical twin) both of which are interconnected via exchange of data in real time. Conceptually, a DT mimics the state of its physical twin ...
    • Heat dissipation plays critical role for longevity of polymer-based 3D-printed inserts for plastics injection moulding. 

      Moritz, Vicente; Bezerra, Gilberto S.N.; Hopkins, Michael Jnr.; Fuenmayor, Evert; Günbay, Suzan; Hayes, Conor; Lyons, John G.; Devine, Declan M. (MDPI, 2022-10-08)
      Injection moulding is a polymer processing method of choice for making plastic parts on industrial scale, but its traditional mould is made from tooling steel with time-consuming and costly production. Additive manufacturing ...
    • Influence of annealing and biaxial expansion on the properties of Poly-l-lactic) medical tubing. 

      Dillon, Brian; Doran, Patrick; Fuenmayor, Evert; Healy, Andrew V.; Gately, Noel M.; Major, Ian; Lyons, John G. (MDPI, 2019-07-11)
      Poly-l-lactic acid (PLLA) is one of the most common bioabsorbable materials in the medical device field. However, its use in load-bearing applications is limited due to its inferior mechanical properties when compared ...
    • The influence of low shear microbore extrusion on the properties of high molecular weight poly(l-lactic acid) for medical tubing applications. 

      Dillon, Brian; Doran, Patrick; Fuenmayor, Evert; Healy, Andrew V.; Gately, Noel M.; Major, Ian; Lyons, John G. (MDPI, 2019-04)
      Biodegradable polymers play a crucial role in the medical device field, with a broad range of applications such as suturing, drug delivery, tissue engineering, sca olding, orthopaedics, and fixation devices. Poly-l-lactic ...
    • Liquid-based 4D printing of shape memory nanocomposites: a review 

      Alsaadi, Mohamad; Hinchy, Eoin P.; McCarthy, Conor T.; Moritz, Vicente F.; Zhuo, Shuo; Fuenmayor, Evert; Devine, Declan M. (MDPI, 2023-01-31)
      Significant advances have been made in recent years in the materials development of liquidbased 4D printing. Nevertheless, employing additive materials such as nanoparticles for enhancing printability and shape memory ...
    • Mass customization of polylactic acid (PLA) parts via a hybrid manufacturing process 

      Gong, Ke; Liu, Handai; Huang, Cheng; Jiang, Qinyu; Xu, Han; Cao, Zhi; Fuenmayor, Evert; Major, Ian (MDPI, 2022-12-10)
      Mass customization is the development of items tailored to specific customers, but produced at low unit cost in high-volume. In this context, hybrid manufacturing (HM) combines fused deposition modeling (FDM) and injection ...
    • Mass-customization of oral tablets via the combination of 3D printing and injection molding. 

      Fuenmayor, Evert; O'Donnell, Crevan; Gately, Noel; Doran, Patrick; Devine, Declan M.; Lyons, John G.; McConville, Christopher; Major, Ian (Elsevier, 2019-10-05)
      The new frontier of medicine is the personalization of treatment to match a patient’s individual needs. Fused-filament fabrication (FFF) offers a platform for the personalization of drug dosage forms, but one of its chief ...
    • Material considerations for fused-filament fabrication of solid dosage forms. 

      Fuenmayor, Evert; Forde, Martin; Healy, Andrew V.; Devine, Declan M.; Lyons, John G.; McConville, Christopher; Major, Ian (MDPI, 2018-04)
      Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, ...
    • Material considerations for fused-filament fabrication of solid dosage forms. 

      Fuenmayor, Evert; Forde, Martin; Healy, Andrew M.; Devine, Declan M.; Lyons, John G.; McConville, Christopher; Major, Ian (MDPI, 2018-04-02)
      Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, ...
    • The production of solid dosage forms from non-degradable polymers. 

      Major, Ian; Fuenmayor, Evert; McConville, Christopher (Bentham Science, 2015)
      Non-degradable polymers have an important function in medicine. Solid dosage forms for longer term implantation require to be constructed from materials that will not degrade or erode over time and also offer the utmost ...
    • Tailoring drug release in bilayer tablets through droplet deposition modeling and injection molding 

      Ebrahimi, Farnoosh; Xu, Han; Fuenmayor, Evert; Major, Ian (Elsevier, 2024-02-01)
      This study explores the innovative production of personalized bilayer tablets, integrating two advanced manufacturing techniques: Droplet Deposition Modeling (DDM) and Injection Molding (IM). Unlike traditional methods ...
    • Transfer and optimisation of injection moulding manufacture of medical devices using scientific moulding principles 

      Fitzgerald, Aimee; McDonald, Paul; Devine, Declan; Fuenmayor, Evert (MDPI, 2021-10-25)
      Scientific moulding, also known as decoupled injection moulding, is a production methodology used to develop and determine robust moulding processes resilient to fluctuations caused by variation in temperature and viscosity. ...