Browsing Articles - Materials Research Institute AIT by Title
Now showing items 53-72 of 96
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Mass-customization of oral tablets via the combination of 3D printing and injection molding.
(Elsevier, 2019-10-05)The new frontier of medicine is the personalization of treatment to match a patient’s individual needs. Fused-filament fabrication (FFF) offers a platform for the personalization of drug dosage forms, but one of its chief ... -
Material considerations for fused-filament fabrication of solid dosage forms.
(MDPI, 2018-04)Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, ... -
Material considerations for fused-filament fabrication of solid dosage forms.
(MDPI, 2018-04-02)Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, ... -
Matrix and reservoir-type multipurpose vaginal rings for controlled release of dapivirine and levonorgestrel
(Elsevier, 2016-09-10)A matrix-type silicone elastomer vaginal ring providing 28-day continuous release of dapivirine (DPV) ⿿ a lead candidate human immunodeficiency virus type 1 (HIV-1) microbicide compound ⿿ has recently demonstrated moderate ... -
Mechanical properties of anodic titanium films containing ions of Ca and P submitted to heat and hydrothermal treatment.
(Elsevier, 2016-12)Anodic oxidation is a technique widely used to improve the bioactivity of Ti surface. In this study, micro-arc oxidation (MAO) was used to obtain an anodic film incorporating Ca and P ions to evaluate the effect of heat ... -
Micro-injection moulding of poly(vinylpyrrolidone-vinyl acetate) binary and ternary amorphous solid dispersions.
(MDPI, 2019-05)Micro-injection moulding (µIM) was used for the production of enteric tablets of plasticised and unplasticised solid dispersions of poly(vinylpyrrolidone-vinyl acetate) (PVPVA), and the effect of the mechanical and thermal ... -
Nanofillers can be used to enhance the thermal conductivity of commercially available SLA resins.
(Elsevier, 2019-06)Stereolithography (SLA) is a form of 3D printing technology used for the production parts and patterns in a layer by layer fashion. Traditionally, 3D printing has been used for the manufacture of prototypes, however it is ... -
Nanosuspension of pinhão seed coat development for a new high-functional cereal bar.
(Wiley, 2020-03-31)The seeds from Araucaria angustifolia—commonly named as pinhão—are important culturally, and viable regional food from Brazil. Although now considered an endangered species, methods to increase the awareness of this tree ... -
A novel pH‐sensitive ceramic‐hydrogel for biomedical applications.
(Wiley, 2015-12)Innovations on the field of smart hydrogels are now being held with loads of advantages. With recent progress, smart polymers can now be used on the market for specific target/objectives desired on medicine. However, the ... -
Optimizing the hardness of SLA printed objects by using the neural netwok and genetic algorithm
(Elsevier, 2019-06)In the developing field of manufacturing, 3D printing is rapidly increasing the horizon of what is possible. However, the possibility of implementing new 3D methods of production has brought new challenges for industries, ... -
Oxide layer containing apatite formed on Ti-25Nb-25Ta alloy treated by two-step plasma electrolytic oxidation.
(Elsevier, 2020-01-25)Hydroxyapatite (HA) is a bioactive calcium phosphate capable of enhancing the implant/bone connection improving osteoconductivity and osseointegration process. However, the HA presents mechanical properties limiting its ... -
Pathogen displacement during intermittent catheter insertion: a novel in vitro urethra model.
(Wiley, 2019-11-29)Aim: To develop a novel in vitro urethra model and use it to determine if insertion of an intermittent urinary catheter (IC) displaces pathogenic bacteria from the urethral meatus along the urethra. Methods: Displacement ... -
Photopolymerization for filling porous ceramic matrix: improvement of mechanical properties and drug delivering behaviour.
(Wiley, 2019-04)This work presents the photopolymerisation of composite scaffolds where a prefabricated ceramic scaffold was impregnated with poly(ethylene) glycol dimethacrylate (PEGDMA) macromonomer solution. The PEGDMA solution penetrates ... -
Platelet-rich plasma, Hydroxyapatite, and Chitosan in the bone and cartilaginous regeneration of femoral trochlea in rabbits: clinical, radiographic, and histomorphometric evaluations.
(Hindawi, 2018-06)The aim of this study was to evaluate the trochlear bone and cartilaginous regeneration of rabbits using the association of PRP, chitosan, and hydroxyapatite. Hole was made in rabbit troches, one hole in each animal ... -
Prediction of yerba mate caffeine content using near infrared spectroscopy.
(Taylor & Francis, 2019-06-10)There is a commercial and beneficial interest of producing yerba mate leaves into different grades of caffeine. This work uses a handheld and bench near infrared spectroscopy to compare and predict, using partial least ... -
Preparation and characterization of novel poly(vinyl) (alcohol) (PVA) and poly(acrylic acid) (PAA) hydrogels for sensitive hydrogels.
(Sciforum, 2014-05)Stimuli Sensitive hydrogels have enormous potential in various applications. Various environmental variables are found in the body, such as low pH and elevated temperatures. For this reason, either pH-sensitive and/or ... -
Preparation of a novel freeze thawed poly (vinly alcohol) composite hydrogel for drug delivery applications
(Elsevier, 2007-09)Poly(vinyl alcohol) (PVA) is a water-soluble, biocompatible and biodegradable polymer, which has been widely applied in biomedical fields. In this paper, novel physically cross-linked hydrogels composed of PVA and comprising ... -
Preparation of biodegradable poltyethylene glycol dimethacrylate hydrogels via thiol-ene chemistry.
(MDPI, 2019-08-13)Through the control of the molecular weight, water content and monomer concentration, polyethylene glycol dimethacrylate (PEGDMA) based hydrogels have been adapted for numerous applications, including as structural scaffolds, ... -
Processing and characterisation of various polymer blends to develop implant for tissue engineering applications.
(AESS, 2013)In the past two decades, the repair and reconstruction of musculoskeletal tissues using biodegradable scaffold materials has emerged as one of the most promising approaches in tissue engineering. The aim of this study ... -
Processing stability and the significance of variation in extrusion speeds and temperture on SSB® 55 Pharma Grade Shellac for Oral Drug Delivery
(MDPI, 2017-09-06)The melt-extrusion process is utilized in the pharmaceutical arena for the manufacturing of a variety of dosage forms and formulations, including solid dispersions. This technology is considered an efficient and continuous ...