Browsing Articles - Materials Research Institute AIT by Title
Now showing items 42-61 of 96
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Impact of torrefaction on properties of Miscanthus x giganteus relevant to gasification.
(Elsevier, 2014-04-01)Miscanthus × giganteus (M × G) was torrefied to improve its thermal and physical properties prior to thermal conversion. Torrefaction was undertaken at a series of temperatures from 230 to 290 °C for residence times varying ... -
In vitro fibroblast and pre-osteoblastic cellular responses on laser surface modified Ti-6AI-4V.
(IOP Publishing, 2014-12-29)The success of any implant, dental or orthopaedic, is driven by the interaction of implant material with the surrounding tissue. In this context, the nature of the implant surface plays a direct role in determining the ... -
Influence of annealing and biaxial expansion on the properties of Poly-l-lactic) medical tubing.
(MDPI, 2019-07-11)Poly-l-lactic acid (PLLA) is one of the most common bioabsorbable materials in the medical device field. However, its use in load-bearing applications is limited due to its inferior mechanical properties when compared ... -
The influence of low shear microbore extrusion on the properties of high molecular weight poly(l-lactic acid) for medical tubing applications.
(MDPI, 2019-04)Biodegradable polymers play a crucial role in the medical device field, with a broad range of applications such as suturing, drug delivery, tissue engineering, sca olding, orthopaedics, and fixation devices. Poly-l-lactic ... -
Injectable bone substitute based on chitosan with polyethylene glycol polymeric solution and biphasic calcium phosphate microspheres.
(Elsevier, 2020-06-10)We described a method to produce an injectable bone substitute consisting of a solid and liquid phase, this solid was formed using the coacervation method consisting of a mixture of Hydroxyapatite (HAp) and beta-Tricalcium ... -
An investigation into the effects of pH and material concentrations on the morphology of Chitosan-Alginate microspheres prepared using an Ionic Gelation technique.
(IJASRM, 2017-10)The aim of this study was to develop microspheres as a drug delivery system using natural polymeric materials including Alginate and Chitosan using an Ionotropic Gelation method of synthesis. In this study, several ... -
Investigation of a novel freeze-thaw process for the production of drug delivery hydrogels
(Springer, 2005-12)Poly(vinyl alcohol) (PVA) is a water-soluble, biocompatible and biodegradable polymer, which has been widely applied in biomedical fields. In this paper, novel physically cross-linked hydrogels composed of PVA and comprising ... -
Investigation of ethylene oxide-co-propylene oxide for dissolution enhancement of hot-melt extruded solid dispersions.
(Elsevier, 2018-02)The optimal design of amorphous solid dispersion (ASD) formulations requires the use of excipients to maintain supersaturation and improve physical stability in order to ensure shelf-life stability and better absorption ... -
Investigation of miscibility estimation methods between indomethacin and poly(vinylpyrrolidone-co-vinyl acetate).
(Elsevier, 2018)The investigation of the miscibility between active pharmaceutical ingredients (API’s) and polymeric excipients is of great interest for the formulation and development of amorphous solid dispersions, especially in the ... -
Investigation of the effects of orientation on freeze/thawed Polyvinyl alcohol hydrogel properties.
(Elsevier, 2018-12)Although hydrogels produced via freeze-thawing (F/T) technique have been thoroughly studied in literature, stretching hydrogels in between freeze-thawing cycles could change its properties and might be modulated for drug ... -
An investigation of the inter-molecular interaction, solid-state properties and dissolution properties of mixed Copovidone hot-melt extruded solid dispersions.
(Elsevier, 2019-10)Previous research has focused on spray dried quaternary mixtures which due to the addition of a surfactant 26 affected the physical stability and amorphous stability of selected model drugs. Very little research has 27 ... -
Mass-customization of oral tablets via the combination of 3D printing and injection molding.
(Elsevier, 2019-10-05)The new frontier of medicine is the personalization of treatment to match a patient’s individual needs. Fused-filament fabrication (FFF) offers a platform for the personalization of drug dosage forms, but one of its chief ... -
Material considerations for fused-filament fabrication of solid dosage forms.
(MDPI, 2018-04)Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, ... -
Material considerations for fused-filament fabrication of solid dosage forms.
(MDPI, 2018-04-02)Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, ... -
Matrix and reservoir-type multipurpose vaginal rings for controlled release of dapivirine and levonorgestrel
(Elsevier, 2016-09-10)A matrix-type silicone elastomer vaginal ring providing 28-day continuous release of dapivirine (DPV) ⿿ a lead candidate human immunodeficiency virus type 1 (HIV-1) microbicide compound ⿿ has recently demonstrated moderate ... -
Mechanical properties of anodic titanium films containing ions of Ca and P submitted to heat and hydrothermal treatment.
(Elsevier, 2016-12)Anodic oxidation is a technique widely used to improve the bioactivity of Ti surface. In this study, micro-arc oxidation (MAO) was used to obtain an anodic film incorporating Ca and P ions to evaluate the effect of heat ... -
Micro-injection moulding of poly(vinylpyrrolidone-vinyl acetate) binary and ternary amorphous solid dispersions.
(MDPI, 2019-05)Micro-injection moulding (µIM) was used for the production of enteric tablets of plasticised and unplasticised solid dispersions of poly(vinylpyrrolidone-vinyl acetate) (PVPVA), and the effect of the mechanical and thermal ... -
Nanofillers can be used to enhance the thermal conductivity of commercially available SLA resins.
(Elsevier, 2019-06)Stereolithography (SLA) is a form of 3D printing technology used for the production parts and patterns in a layer by layer fashion. Traditionally, 3D printing has been used for the manufacture of prototypes, however it is ... -
Nanosuspension of pinhão seed coat development for a new high-functional cereal bar.
(Wiley, 2020-03-31)The seeds from Araucaria angustifolia—commonly named as pinhão—are important culturally, and viable regional food from Brazil. Although now considered an endangered species, methods to increase the awareness of this tree ... -
A novel pH‐sensitive ceramic‐hydrogel for biomedical applications.
(Wiley, 2015-12)Innovations on the field of smart hydrogels are now being held with loads of advantages. With recent progress, smart polymers can now be used on the market for specific target/objectives desired on medicine. However, the ...