Browsing Articles - PRISM: Polymer, Recycling, Industrial, Sustainability and Manufacturing Institute by Title
Now showing items 12-31 of 169
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A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix
(MDPI, 2020-12-06)This study was performed to develop an adjuvant therapy in the form of a self-administered vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to reduce relapse by eradicating ... -
Bioactive composites fabricated by freezing-thawing method for bone regeneration applications.
(Wiley, 2016-04)Hydrogels are widely used for controlled delivery of therapeutic agents. However, hydrogels lack bioactivity to encourage bone formation and mechanical integrity. Moreover, chemically crosslinked hydrogels exhibit cytotoxic ... -
Biodegradation and antimicrobial properties of zinc oxide-polymer composite materials for urinary stent applications
(MDPI, 2020-10-20)Research advancements in the field of urinary stents have mainly been in the selection of materials and coatings to address commonly faced problems of encrustation and bacterial adhesion. In this study, polylactic acid ... -
Bioresorbable chitosan-based bone regeneration scaffold using various bioceramics and the alteration of photoinitiator concentration in an extended UV photocrosslinking reaction in an extended UV photocrosslinking reaction
(MDPI, 2022-10-28)Bone tissue engineering (BTE) is an ongoing field of research based on clinical needs to treat delayed and non-union long bone fractures. An ideal tissue engineering scaffold should have a biodegradability property ... -
Bone tissue engineering scaffold optimisation through modification of Chitosan/ceramic composition
(MDPI, 2023-06-01)A large bone defect is defined as a defect that exceeds the regenerative capacity of the bone. Nowadays, autologous bone grafting is still the gold standard treatment. In this study, a hybrid bone tissue engineering scaffold ... -
Boosting bacterial nanocellullose production from chemically recycled post-consumer polyethylene terephthalate
(Elsevier, 2024-04)The circular economy is emerging with new sustainable solutions to the ever-growing plastic waste challenge, garnering increasing attention. In this study, the possibility to modify expensive Hestrin–Schramm medium (HS) for ... -
Characterisation and in vivo evaluation of Araucaria angustifolia pinhão seed coat nanosuspension as a functional food source
(Royal Society of Chemistry, 2020-10-08)Araucaria angustifolia seeds are culturally important from South America; however, the seed coat is generally discarded and have yet to find a beneficial commercial impact. We propose a new formulation to the usage of ... -
Characteristics of the treated calcium carbonate particles with stearic acid using different treating methods.
(Elsevier, 2016-08)Calcium carbonate (CaCO3) is often treated with stearic acid (SA) to decrease its polarity. However, the method of application of the SA treatments has a strong influence on their interface structure and distribution. ... -
Characterization of gels and films produced from Pinhão seed coat nanocellulose as a potential use for wound healing dressings and screening of Its compounds towards antitumour effects
(MDPI, 2022-07-07)The reuse of agro-industrial waste assumes great importance today. Pinhão is the seed of Araucaria angustifolia, which is native to the mountains of southern Brazil, Paraguay, and Argentina. The coat is a by-product of ... -
Chitosan/hydroxyapatite scaffolds with P28 as a promising osteoinductive scaffold for bone healing applications
(MDPI, 2023-01-31)Despite bone’s inherent ability to heal, large bone defects remain a major clinical concern. This study proposes an off-the-shelf treatment combining chitosan/hydroxyapatite (CS/HAp) scaf folds, covalently linked with ... -
Comparison of fused-filament fabrication to direct compression and injection molding in the manufacture of oral tablets.
(Elsevier, 2019-03-10)Oral tablets are a convenient form to deliver active pharmaceutical ingredients (API) and have a high level of acceptance from clinicians and patients. There is a wide range of excipients available for the fabrication of ... -
Composite cryogels for dual drug delivery and enhanced mechanical properties.
(Wiley, 2018-04)In this study, we present a simple and effective process that integrates hydrogels with drugs + ceramics via physical crosslinks resulting in improved mechanical properties. These cryogels have the potential for controlled ... -
Composite films of thermoplastic starch and CaC12 extracted from eggshells for extendiing food shelf-life
(MDPI, 2021-09-03)Calcium chloride (CaCl2) has been widely used to maintain the quality of fresh-cut fruits and vegetables because it stabilizes and strengthens the membrane system against fungal attacks. It is mainly applied via spray ... -
Comprehensive analysis and assessment of exposure to enteric viruses and bacteria in shellfish
(Elsevier, 2024-02-08)Shellfish species, including oysters, clams, and mussels, are extensively cultured in coastal waters. Its location is determined by factors such as nutrient availability, water temperature, tidal cycle, and the presence ... -
Degradable nanocomposites for fused filament fabrication applications.
(MDPI, 2018-05-09)There has been a substantial increase in the use and development of plastics over the last century. However, due to ever-diminishing petroleum feedstocks and growing concern for the environment, there has been a rise in ... -
Design, development and in vitro quantification of novel electrosprayed everolimus-loaded Soluplus®/Polyvinyl alcohol nanoparticles via stability-indicating HPLC method in cancer therapy
(Elsevier, 2023-09-14)Everolimus (RAD001) a mammalian target of rapamycin has been hampered by poor solubility, affecting its dissolution rate, a relationship that extends to low bioavailability. Nanoparticles (NP) based on Soluplus (SOL®) and ... -
Designing sustainable polymer blends: tailoring mechanical properties and degradation behaviour in PHB/PLA/PCL blends in a seawater environment
(MDPI, 2023-06-29)Biodegradable polyesters are a popular choice for both packaging and medical device manufacture owing to their ability to break down into harmless components once they have completed their function. However, commonly used ... -
The development of a melt-extruded shellac carrier for the targeted delivery of probiotics to the colon.
(MDPI, 2017-12)Hot melt extrusion (HME) is considered an efficient technique in developing solid molecular dispersions, and has been demonstrated to provide sustained, modified and targeted drug delivery resulting in improved ... -
Development of a multi-layered vaginal tablet containing Dapivirine, Levonorgestrel and Acyclovir for use as a multipurpose prevention technology.
(Elsevier, 2016-07)Multipurpose prevention technologies (MPTs) are preferably single dosage forms designed to simultaneously address multiple sexual and reproductive health needs, such as unintended pregnancy, HIV infection and other ... -
Development of alginate beads with encapsulated jabuticaba peel and propolis extracts to achieve a new natural colorant antioxidant additive.
(Elsevier, 2020-07)This work aims to encapsulate anthocyanins and phenolic compounds extracted from a native Brazilian fruit peel - jabuticaba (Plinia cauliflora (Mart.) Kausel) and propolis from Tubuna (Scaptotrigona bipunctata) stingless ...