Browsing Articles - Materials Research Institute AIT by Title
Now showing items 3-22 of 96
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Additive manufacturing of personalized pharmaceutical dosage forms via stereolithography.
(MDPI, 2019-12-03)The introduction of three-dimensional printing (3DP) has created exciting possibilities for the fabrication of dosage forms, paving the way for personalized medicine. In this study, oral dosage forms of two drug ... -
Additive manufacturing of PLA/HNT nanocomposites for biomedical applications
(Elsevier, 2019)Additive manufacturing has been of great interest of research in various applications due to their ease in processability, cost effectiveness and adaptability. In this study Poly Lactic Acid (PLA) was used as the base ... -
Alfa fiber/polypropylene composites: Influence of fiber extraction method and chemical treatments.
(Wiley, 2019-01)Alfa fiber/polypropylene composites were manufactured using twin-screw extrusion. Fibers were extracted following alkaline and steam explosion methods. Three chemical treatments were also applied to alkaline extracted ... -
Analysis of the mechanical properties of solvent cast blends of PLA/PCL.
(Trans Tech Publications, 2014-09)Polylactic acid (PLA) is the most promising material in the biodegradable category. However, brittleness and poor thermal stability restrict its application. To overcome this limitation, PLA may be blended with other ... -
A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix
(MDPI, 2020-12-06)This study was performed to develop an adjuvant therapy in the form of a self-administered vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to reduce relapse by eradicating ... -
Bioactive composites fabricated by freezing-thawing method for bone regeneration applications.
(Wiley, 2016-04)Hydrogels are widely used for controlled delivery of therapeutic agents. However, hydrogels lack bioactivity to encourage bone formation and mechanical integrity. Moreover, chemically crosslinked hydrogels exhibit cytotoxic ... -
Biodegradation and antimicrobial properties of zinc oxide-polymer composite materials for urinary stent applications
(MDPI, 2020-10-20)Research advancements in the field of urinary stents have mainly been in the selection of materials and coatings to address commonly faced problems of encrustation and bacterial adhesion. In this study, polylactic acid ... -
Characterisation and in vivo evaluation of Araucaria angustifolia pinhão seed coat nanosuspension as a functional food source
(Royal Society of Chemistry, 2020-10-08)Araucaria angustifolia seeds are culturally important from South America; however, the seed coat is generally discarded and have yet to find a beneficial commercial impact. We propose a new formulation to the usage of ... -
Characteristics of the treated calcium carbonate particles with stearic acid using different treating methods.
(Elsevier, 2016-08)Calcium carbonate (CaCO3) is often treated with stearic acid (SA) to decrease its polarity. However, the method of application of the SA treatments has a strong influence on their interface structure and distribution. ... -
Comparison of fused-filament fabrication to direct compression and injection molding in the manufacture of oral tablets.
(Elsevier, 2019-03-10)Oral tablets are a convenient form to deliver active pharmaceutical ingredients (API) and have a high level of acceptance from clinicians and patients. There is a wide range of excipients available for the fabrication of ... -
Composite cryogels for dual drug delivery and enhanced mechanical properties.
(Wiley, 2018-04)In this study, we present a simple and effective process that integrates hydrogels with drugs + ceramics via physical crosslinks resulting in improved mechanical properties. These cryogels have the potential for controlled ... -
Degradable nanocomposites for fused filament fabrication applications.
(MDPI, 2018-05-09)There has been a substantial increase in the use and development of plastics over the last century. However, due to ever-diminishing petroleum feedstocks and growing concern for the environment, there has been a rise in ... -
The development of a melt-extruded shellac carrier for the targeted delivery of probiotics to the colon.
(MDPI, 2017-12)Hot melt extrusion (HME) is considered an efficient technique in developing solid molecular dispersions, and has been demonstrated to provide sustained, modified and targeted drug delivery resulting in improved ... -
Development of a multi-layered vaginal tablet containing Dapivirine, Levonorgestrel and Acyclovir for use as a multipurpose prevention technology.
(Elsevier, 2016-07)Multipurpose prevention technologies (MPTs) are preferably single dosage forms designed to simultaneously address multiple sexual and reproductive health needs, such as unintended pregnancy, HIV infection and other ... -
Development of alginate beads with encapsulated jabuticaba peel and propolis extracts to achieve a new natural colorant antioxidant additive.
(Elsevier, 2020-07)This work aims to encapsulate anthocyanins and phenolic compounds extracted from a native Brazilian fruit peel - jabuticaba (Plinia cauliflora (Mart.) Kausel) and propolis from Tubuna (Scaptotrigona bipunctata) stingless ... -
Development of Amoxicillin loaded microspheres for anti-Helicobacter pylori infection using Ionic Gelation method
(IJASRM, 2017-11)The aim of this project was to develop microspheres loaded with Amoxicillin for anti-Helicobacter pylori infection. Amoxicillin loaded microspheres were developed using blends of natural polymers such as Alginate and ... -
Development of disulfiram-loaded vaginal rings for the localised treatment of cervical cancer.
(Elsevier, 2014-11)Cervical cancer is the third most prevalent cancer in women and disproportionately affects those in low resource settings due to limited programs for screening and prevention. In the developed world treatment for the disease ... -
Development of synthetic alternatives for bone tissue engineering.
(Australian Journal of Basic and Applied Sciences, 2013)Due to the inherent limitations of current biological bone grafts, alternative synthetic substitutes are being pursued. Therefore, this study aimed to improve the bioactive and compressive properties of photopolymerisable ... -
Dielectric polarization enhancement of thermoplastic elastomers for sensing and energy harvesting applications.
(IJMMM, 2016-11)Nano-structured dielectric thermoplastic elastomers (DTEs) such as poly(styrene-co-ethylene-co-butylene-styrene) [SEBS] and poly(styrene-co-ethylene-co-butylene-styrene) –grafted- maleic anhydride[SEBS-g-MA] triblock ... -
Durum wheat seed germination response to hydrogel coatings and moisture under drought stress.
(Science Publications, 2016-11)Abstract: Technologies that can increase crop production while maintaining low pollution are essential for sustainable agriculture. This study compares the germination performance of Durum wheat seeds (Triticum durum ...