Browsing Articles - Bioscience Research Institute (BRI) by Issue Date
Now showing items 21-40 of 72
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β-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in-vitro immunomodulatory and pulmonary cytoprotective effects — Implications for coronavirus disease (COVID-19) immunotherapies.
(Elsevier, 2020-05-11)Coronavirus pneumonia is accompanied by rapid virus replication, where a large number of inflammatory cell infiltration and cytokine storm may lead to acute lung injury, acute respiratory distress syndrome (ARDS) and death. ... -
Performance of mycelial biomass and exopolysacccharide from Malaysian Ganoderma lucidum for the fungivore red hybrid Tilapia (Oreochromis sp.) in Zebrafish embyro.
(Elsevier, 2020-07)Natural mycelial biomass (MB) and extracted exopolysaccharide (EPS) from the pre-grown Malaysian Ganoderma lucidum mushroom are both considered as high-end materials due to their high commercial value in the aquaculture ... -
Purified β‐glucans from the Shiitake mushroom ameliorates antibiotic‐resistant Klebsiella pneumoniae‐induced pulmonary sepsis
(Society for Applied Microbiology, 2020-07-24)Bacterial infection remains the main cause of acute respiratory distress syndrome and is a leading cause of death and disability in critically ill patients. Here we report on the use of purified β‐glucan (lentinan) extracts ... -
Mechanism of formation, characterization and cytotoxicity of green synthesized zinc nanoparticles obtained from Ilex paraguariensis leaves extract
(Elsevier, 2020-10)Zinc oxide nanoparticles (ZnONPs) was produced using Ilex paraguariensis (mate) leaves extract using a green synthesis process. The influence of ethanolic and aqueous plant extract and zinc source on the green synthesis ... -
The European media portrayal of climate change: implications for the social mobilization towards climate action
(MDPI, 2020-10-09)Beyond other social actors, such as policymakers and scholars, common citizens are also expected to actively engage with climate change, by adopting sustainable actions and supporting environmental policies. However, and ... -
Pellet diameter of ganoderma lucidum in a repeated-batch fermentation for the trio total production of biomass-exopolysaccharide-exopolysaccharid and its anti-oral cancer beta-glucan response
(AIMS, 2020-10-22)The pellet morphology and diameter range (DR) of Ganoderma lucidum were observed in a repeated-batch fermentation (RBF) for the trio total production of biomass, exopolysaccharide (EPS) and endopolysaccharide (ENS). Two ... -
A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix
(MDPI, 2020-12-06)This study was performed to develop an adjuvant therapy in the form of a self-administered vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to reduce relapse by eradicating ... -
β-glucan metabolic and immunomodulatory properties and potential for clinical application
(MDPI, 2020-12-10)β-glucans are complex polysaccharides that are found in several plants and foods, including mushrooms. β-glucans display an array of potentially therapeutic properties. β-glucans have metabolic and gastro-intestinal effects, ... -
Unlocking challenges and opportunities presented by Covid-19 pandemic for cross-cutting disruption in agri-food and green deal innovations: quo vadis?
(Elsevier, 2020-12-15)COVID-19 pandemic is on a trajectory to cause catastrophic global upheaval with the potential to alter geopolitical and socio-economic norms. Many countries are frantically responding with staggering financial stimulus ... -
Integrative genomics of the mammalian alveolar macrophage response to intraceullular mycobacteria
(BMC, 2021)Bovine TB (bTB), caused by infection with Mycobacterium bovis, is a major endemic disease affecting global cattle production. The key innate immune cell that first encounters the pathogen is the alveolar macrophage, ... -
Unlocking the surge in demand for personal and protective equipment (PPE) and improvised face coverings arising from coronavirus disease (COVID-19) pandemic – Implications for efficacy, re-use and sustainable waste management
(Elsevier, 2021)Currently, there is no effective vaccine for tackling the ongoing COVID-19 pandemic caused by SARS-CoV-2 with the occurrence of repeat waves of infection frequently stretching hospital resources beyond capacity. Disease ... -
Disposable face masks and reusable face coverings as non-pharmaceutical interventions (NPIs) to prevent transmission of SARS-CoV-2 variants that cause coronavirus disease (COVID-19): Role of new sustainable NPI design innovations and predictive mathematical modelling
(Elsevier, 2021-02-01)Best-published evidence supports the combined use of vaccines with non-pharmaceutical interventions (NPIs), to reduce the relative risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes ... -
Investigations on the use of exopolysaccharide derived from mycelial extract of Ganoderma lucidum as functional feed ingredient for aquaculture-farmed red hybrid Tilapia ( Oreochromis sp.)
(Elsevier, 2021-02-03)There is growing interest in medicinal fungi for promoting immunomodulation benefits in humans and animals. In this study, exopolysaccharide (EPS) from Ganoderma lucidum was used in feed (EFF) on production of farmed-red ... -
Use of Zebrafish embryo assay to evaluate toxicity and safety of bioreactor-grown exopolysaccharides and endopolysaccharides from European Ganoderma applanatum mycelium for future aquaculture applications
(MDPI, 2021-02-07)Natural mycelial exopolysaccharide (EPS) and endopolysaccharide (ENS) extracted from bioreactor-cultivated European Ganoderma applanatum mushrooms are of potential high commercial value for both food and adjacent ... -
Disease-mitigating innovations for the pollination service industry: challenges and opportunities
(Elsevier, 2021-04)Commercially reared bumblebees are often deployed for fruit, vegetable, and seed crop pollination. Commercial bumblebee pollination contributes significantly to economic and nutritional security, thus maintaining healthy ... -
Bacterial inactivation, photoreactivation and dark repair post flow-through pulsed IV disinfection
(Elsevier, 2021-04-19)Pulsed UV (PUV) technology is accepted commercially for disinfection within the food packaging industry, but has yet to be deployed by the water/wastewater sector. This is partly due to a lack of robust, independently ... -
Genomes of Anguillid Herpesvirus 1 strains reveal evolutionary disparities and low genetic diversity in the Genus Cyprinivirus
(MDPI, 2021-05-05)Anguillid herpesvirus 1 (AngHV-1) is a pathogen of eels and a member of the genus Cyprinivirus in the family Alloherpesviridae. We have compared the biological and genomic fea tures of different AngHV-1 strains, focusing ... -
Empower Eco multiactor HUB: A triple helix ‘academia-industry-authority’ approach to creating and sharing potentially disruptive tools for addressing novel and emerging new Green Deal opportunities under a United Nations Sustainable Development Goals framework
(Elsevier, 2021-06)There is a pressing drive to address climate change and environmental degradation that are global existential threats. Europe has strategically responded by unifying efforts to transform its connected communities into ... -
Development of a low-temperature extrusion process for production of GRAS bioactive-polymer loaded compounds for targeting antimicrobial-resistant (AMR) bacteria
(Elsevier, 2021-08-10)Antimicrobial resistance (AMR) is recognised globally as one of the greatest threats to human and animal health; thus, discovery of alternative antibacterial agents to address AMR is a priority challenge. This study ... -
In-vivo toxicity of bioreactor-grown biomass and exopolysaccharides from Malaysian Tiger milk mushroom mycelius for potential future health applications
(Nature Research, 2021-08-12)Natural mycelial biomass (MB) and exopolysaccharide (EPS) produced from bioreactor-grown Malaysian Tiger Milk Mushroom Lignosus rhinocerus are considered high-end components due to their high commercial potential value in ...