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Single nucleotide polymorphisms in the growth hormone and insulin-like growth factor-1 genes are associated with milk production, body condition score and fertility traits in dairy cows.
(GMR, 2011-08-26)
The somatotrophic axis (GH-IGF) is a key regulator
of animal growth and development, affecting performance traits that
include milk production, growth rate, body composition, and fertility.
The aim of this study was to ...
Single nucleotide polymorphisms in the insulin-like growth factor 1 (IGF-1) gene are associated with performance in Holstein-Friesian dairy cattle.
(Frontiers, 2011-02-16)
Insulin-like growth factor 1 (IGF-1) has been shown to be associated with fertility, growth,
and development in cattle. The aim of this study was to (1) identify novel single nucleotide
polymorphisms (SNPs) in the bovine ...
DNA sequence polymorphisms in a panel of eight candidate bovine imprinted genes and their association with performance traits in Irish Holstein-Friesian cattle.
(BMC, 2010-10-13)
Background: Studies in mice and humans have shown that imprinted genes, whereby expression from one of the
two parentally inherited alleles is attenuated or completely silenced, have a major effect on mammalian ...
Investigation of prolific sheep from UK and Ireland for evidence on origin of the mutations in BMP15 (FecXG, FecXB) and GDF9 (FecGH) in Belclare and Cambridge sheep.
(PLOS, 2013-01)
This paper concerns the likely origin of three mutations with large effects on ovulation rate identified in the Belclare and
Cambridge sheep breeds; two in the BMP15 gene (FecXG and FecXB) and the third (FecGH) in GDF9. ...
Associations between the K232A polymorphism in the diacylglycerol-O-transferase 1 (DGAT1) gene and performance in Irish Holstein-Friesian dairy cattle
(Teagasc, 2010)
Selection based on genetic polymorphisms requires accurate quantification of the
effect or association of the polymorphisms with all traits of economic importance.
The objective of this study was to estimate, using progeny ...
Polymorphism discovery and allele frequency estimation using high-throughput DNA sequencing of target-enriched pooled DNA samples
(BMC, 2012-01-11)
Background: The central role of the somatotrophic axis in animal post-natal growth, development and fertility is
well established. Therefore, the identification of genetic variants affecting quantitative traits within ...
A note on the use of FTA™ technology for storage of blood samples for DNA analysis and removal of PCR inhibitors
(Sciendo, 2009-01)
FTA™ technology is widely used across many molecular disciplines for sample
capture, storage and analysis. The use of this technology for the long-term storage
of blood samples for DNA analysis was examined as well as ...
DNA sequence polymorphisms within the bovine guanine nucleotide-binding protein Gs subunit alpha (Gsα)-encoding (GNAS) genomic imprinting domain are associated with performance traits
(BMC, 2011-01-11)
Background: Genes which are epigenetically regulated via genomic imprinting can be potential targets for artificial
selection during animal breeding. Indeed, imprinted loci have been shown to underlie some important ...