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Characterisation of biopharmaceuticals
(The Institute of Chemistry of Ireland, 2016-07)
Biopharmaceuticals are drugs which are primarily (glyco)protein in nature, that are produced in living cells
using recombinant DNA technology – the combination of genetic material from multiple sources, creating
sequences ...
Preparation and characterization of the ‘research chemical’ diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers.
(Wiley, 2015-05)
Substances with the diphenylethylamine nucleus represent a recent addition to the
product catalog of dissociative agents sold as research chemicals on the Internet.
Diphenidine, i.e. 1-(1,2-diphenylethyl)piperidine ...
Test purchase, synthesis and characterization of 3-fluorophenmetrazine (3-FPM) and differentiation from its ortho- and para-substituted isomers
(Wiley, 2017-03)
The knowledge captured in patent and scientific research literature stimulates
new ideas and fosters new drug development efforts. Manufacturers and
entrepreneurs dedicated to the sale of ‘research chemicals’ and/or ...
Prediction of toxigenic fungal growth in buildings by using a novel modelling system.
(American Society for Microbiology, 1999-11)
There is growing concern about the adverse effects of fungal bioaerosols on the occupants of damp dwellings.
Based on an extensive analysis of previously published data and on experiments carried out within this ...
Advanced therapies and the outer limits of DNA regulation: new horizons for patents or a scaffold too far?
(Oxford Academic, 2008-04)
This Regulation seeks to regulate existing and future advanced therapy medicinal products intended for the market in Member States, being either prepared industrially or manufactured by a method involving an industrial ...
Detection, toxicology, environmental fate and risk assessment of nanoparticles in the aquatic environment (DeTER)
(EPA, 2018)
Nanotechnology is an emerging technology that
has the potential to impact on all aspects of life and
the economy and is expected to form the basis of
several technological innovations and advances
in the 21st century. ...
Synthesis, characterization and monoamine transporter activity of the new psychoactive substance 3’,4’-methylenedioxy-4-methylaminorex (MDMAR).
(Wiley, 2015-07)
The recent occurrence of deaths associated with the psychostimulant cis-4,4'-dimethylaminorex (4,4'-DMAR) in Europe indicated the presence of a newly emerged psychoactive substance on the market. Subsequently, the existence ...
Analytical characterization and pharmacological evaluation of the new psychoactive substance 4-fluoromethylphenidate (4F-MPH) and differentiation between the (±)-threo- and (±)-erythro- diastereomers
(Wiley, 2017-03)
Misuse of (±)-threo-methylphenidate (methyl-2-phenyl-2-(piperidin-2-yl)acetate; Ritalin®; MPH) has long been acknowledged, but the appearance of MPH analogs in the form of 'research chemicals' has only emerged in more ...
The synthesis and characterization of the ‘research chemical’ N-(1- amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl) -1H-pyrazole-5-carboxamide (3,5-AB-CHMFUPPYCA) and differentiation from its 5,3-regioisomer.
(Wiley, 2016-09)
This study presents the identification of N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-
(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide that was termed
3,5-AB-CHMFUPPYCA. This compound was obtained from a ...
Microbiological degradation of pesticides in yard waste composting.
(American Society for Microbiology, 1991)
Changes in public opinion and legislation have led to the general recognition that solid waste treatment practices must be changed. Solid-waste disposal by landfill is becoming increasingly expensive and regulated and no ...