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Characterisation of biopharmaceuticals
(The Institute of Chemistry of Ireland, 2016-07)
Biopharmaceuticals are drugs which are primarily (glyco)protein in nature, that are produced in living cells
using recombinant DNA technology – the combination of genetic material from multiple sources, creating
sequences ...
Preparation and characterization of the ‘research chemical’ diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers.
(Wiley, 2015-05)
Substances with the diphenylethylamine nucleus represent a recent addition to the
product catalog of dissociative agents sold as research chemicals on the Internet.
Diphenidine, i.e. 1-(1,2-diphenylethyl)piperidine ...
Single nucleotide polymorphisms in the growth hormone and insulin-like growth factor-1 genes are associated with milk production, body condition score and fertility traits in dairy cows.
(GMR, 2011-08-26)
The somatotrophic axis (GH-IGF) is a key regulator
of animal growth and development, affecting performance traits that
include milk production, growth rate, body composition, and fertility.
The aim of this study was to ...
Untreated and enzyme-modified bovine whey products reduce association of Salmonella typhinurim, Escherichia coli O157:H7 and Cronobactermalonaticus (formerly Enterobacter sakazakii) to CaCo-2 cells.
(Wiley, 2010-02)
Aims: Adhesion of a micro-organism to a cell surface is often considered to be
the first step in pathogenesis. Inhibiting this process may have therapeutic
effects in vivo. This study investigates the inhibitory effects ...
Test purchase, synthesis and characterization of 3-fluorophenmetrazine (3-FPM) and differentiation from its ortho- and para-substituted isomers
(Wiley, 2017-03)
The knowledge captured in patent and scientific research literature stimulates
new ideas and fosters new drug development efforts. Manufacturers and
entrepreneurs dedicated to the sale of ‘research chemicals’ and/or ...
Influence of reconstitution temperature on survival of Cronobacter Sakazakii in powdered infant formula.
(Slovak University of Agriculture in Nitra. Faculty of Biotechnology and Food Sciences., 2016-04)
Cronobacter spp. are emerging opportunistic pathogens commonly associated with the feeding of powdered infant formula (PIF). This study aimed to investigate the ability of C.sakazakii (ATCC 29544) to survive heat injury ...
Detection, toxicology, environmental fate and risk assessment of nanoparticles in the aquatic environment (DeTER)
(EPA, 2018)
Nanotechnology is an emerging technology that
has the potential to impact on all aspects of life and
the economy and is expected to form the basis of
several technological innovations and advances
in the 21st century. ...
Synthesis, characterization and monoamine transporter activity of the new psychoactive substance 3’,4’-methylenedioxy-4-methylaminorex (MDMAR).
(Wiley, 2015-07)
The recent occurrence of deaths associated with the psychostimulant cis-4,4'-dimethylaminorex (4,4'-DMAR) in Europe indicated the presence of a newly emerged psychoactive substance on the market. Subsequently, the existence ...
Analytical characterization and pharmacological evaluation of the new psychoactive substance 4-fluoromethylphenidate (4F-MPH) and differentiation between the (±)-threo- and (±)-erythro- diastereomers
(Wiley, 2017-03)
Misuse of (±)-threo-methylphenidate (methyl-2-phenyl-2-(piperidin-2-yl)acetate; Ritalin®; MPH) has long been acknowledged, but the appearance of MPH analogs in the form of 'research chemicals' has only emerged in more ...
The synthesis and characterization of the ‘research chemical’ N-(1- amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl) -1H-pyrazole-5-carboxamide (3,5-AB-CHMFUPPYCA) and differentiation from its 5,3-regioisomer.
(Wiley, 2016-09)
This study presents the identification of N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-
(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide that was termed
3,5-AB-CHMFUPPYCA. This compound was obtained from a ...