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Preparation and characterization of the ‘research chemical’ diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers.
(Wiley, 2015-05)
Substances with the diphenylethylamine nucleus represent a recent addition to the
product catalog of dissociative agents sold as research chemicals on the Internet.
Diphenidine, i.e. 1-(1,2-diphenylethyl)piperidine ...
Test purchase, synthesis and characterization of 3-fluorophenmetrazine (3-FPM) and differentiation from its ortho- and para-substituted isomers
(Wiley, 2017-03)
The knowledge captured in patent and scientific research literature stimulates
new ideas and fosters new drug development efforts. Manufacturers and
entrepreneurs dedicated to the sale of ‘research chemicals’ and/or ...
Synthesis, characterization and monoamine transporter activity of the new psychoactive substance 3’,4’-methylenedioxy-4-methylaminorex (MDMAR).
(Wiley, 2015-07)
The recent occurrence of deaths associated with the psychostimulant cis-4,4'-dimethylaminorex (4,4'-DMAR) in Europe indicated the presence of a newly emerged psychoactive substance on the market. Subsequently, the existence ...
Analytical characterization and pharmacological evaluation of the new psychoactive substance 4-fluoromethylphenidate (4F-MPH) and differentiation between the (±)-threo- and (±)-erythro- diastereomers
(Wiley, 2017-03)
Misuse of (±)-threo-methylphenidate (methyl-2-phenyl-2-(piperidin-2-yl)acetate; Ritalin®; MPH) has long been acknowledged, but the appearance of MPH analogs in the form of 'research chemicals' has only emerged in more ...
The synthesis and characterization of the ‘research chemical’ N-(1- amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl) -1H-pyrazole-5-carboxamide (3,5-AB-CHMFUPPYCA) and differentiation from its 5,3-regioisomer.
(Wiley, 2016-09)
This study presents the identification of N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-
(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide that was termed
3,5-AB-CHMFUPPYCA. This compound was obtained from a ...
Synthesis, analytical characterization and monoamine transporter activity of the new psychoactive substance 4- methylphenmetrazine (4-MPM), with differentiation from its ortho- and meta- positional isomers
(Wiley, 2018-09)
The availability of new psychoactive substances on the recreational drug
market continues to create challenges for scientists in the forensic, clinical
and toxicology fields. Phenmetrazine (3-methyl-2-phenylmorpholine) ...
Synthesis, characterization and monoamine transporter activity of the new psychoactive substance mexedrone and its N-methoxy positional isomer, N-methoxymephedrone.
(Wiley, 2017-03)
3-Methoxy-2-(methylamino)-1-(4-methylphenyl)propan-1-one (mexedrone)
appeared in 2015 and was advertised by UK Internet retailers as a noncontrolled
mephedrone derivative (2-(methylamino)-1-(4-
methylphenyl)propan-1-one), ...
Fluorinated phenmetrazine “legal highs” act as substrates for high-affinity monoamine transporters of the SLC6 family.
(Elsevier, 2018-05-15)
A variety of new psychoactive substances (NPS) are appearing in recreational drug markets worldwide.
NPS are compounds that target various receptors and transporters in the central nervous system to
achieve their ...
In vitro metabolism of the synthetic cannabinoid 3,5‐AB‐CHMFUPPYCA and its 5,3‐regioisomer and investigation of their thermal stability.
(Wiley, 2016-02)
Recently, the pyrazole‐containing synthetic cannabinoid N‐(1‐amino‐3‐methyl‐1‐oxobutan‐2‐yl)‐1‐(cyclohexylmethyl)‐3‐(4‐fluorophenyl)‐1H‐pyrazole‐5‐carboxamide (3,5‐AB‐CHMFUPPYCA) has been identified as a ‘research chemical’ ...