Browsing Articles - Department of Pharmaceutical Sciences and Biotechnology by Author "Spillane, Charles"
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DNA sequence polymorphisms in a panel of eight candidate bovine imprinted genes and their association with performance traits in Irish Holstein-Friesian cattle.
Magee, David A.; Sikora, Klaudia M.; Berowicz, Erik W.; Berry, Donagh P.; Howard, Dawn J.; Mullen, Michael P.; Evans, Ross D.; Spillane, Charles; MacHugh, David E. (BMC, 2010-10-13)Background: Studies in mice and humans have shown that imprinted genes, whereby expression from one of the two parentally inherited alleles is attenuated or completely silenced, have a major effect on mammalian ... -
DNA sequence polymorphisms within the bovine guanine nucleotide-binding protein Gs subunit alpha (Gsα)-encoding (GNAS) genomic imprinting domain are associated with performance traits
Kikora, Klaudia M.; Magee, David A.; Berkowicz, Erik W.; Berry, Donagh P.; Howard, Dawn; Mullen, Michael P.; Evans, Ross D.; MacHugh, David E.; Spillane, Charles (BMC, 2011-01-11)Background: Genes which are epigenetically regulated via genomic imprinting can be potential targets for artificial selection during animal breeding. Indeed, imprinted loci have been shown to underlie some important ...