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Evaluation of the efficacy of lipid core nanoemulsions containing temozolomide coupled to ferrocenes in the treatment of Glioblastomas
(Athlone Institute of Technology, 2020)
Glioblastoma (GB) is the most common and aggressive neoplastic brain tumor, and its treatment has proved to be a challenge.
For decades its therapy has been based on the use of temozolomide (TMZ), but the survival rate ...
Preclinical assessment of biomimetic and bioactive bone regeneration scaffold in femoral condyle defect of Sprague Dawley rats.
(Athlone Institute of Technology, 2020)
A fabricated biomimetic bone scaffold, incorporating osteogenic factors, presents a promising alternative to traditional autologous and
allogeneic bone fracture treatments. Here, the principles of biology and engineering ...
Development of novel polyethylene glycol dimethacrylate (PEGDMA)-based hydrogels for never regeneration
(Athlone Institute of Technology, 2020-06)
Injury to the peripheral nervous system (PNS) affects more than 1,000,000 people worlwide a year. It is estimated that $150 billion is spent on nerve injury repair in the USA alone each year. The current surgical methods ...
Development of a new bone scaffold for the treatment of large bone defects
(Athlone Institute of Technology, 2020-06)
Large bone defects
are typically caused by incidents
such
as fractures, diseases, trauma or surgeries. Worldwide more that 3/5 million bone grafts (either autografts or allografts) are performed each year.
The effect of cooling on the degree of crystallinity, solid-state properties, and dissolution rate of multi-component hot-melt extruded solid dispersions.
(MDPI, 2020-03-01)
The effect of cooling on the degree of crystallinity, solid-state and dissolution properties
of multi-component hot-melt extruded solid dispersions [SD] is of great interest for the successful
formulation of amorphous ...
Development of smart 4-D materials utilising novel self assembly polymers
(2020-06)
4D printing is a technique that uses a 3 D printer to create objects that change their
shape overtime 4 D printing involves the use of smart materials that will transform when
exposed to an external stimuli These can ...