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Now showing items 81-90 of 90
Development, characterization and cell viability inhibition of PVA spheres loaded with Doxorubicin and 4′-Amino-1-Naphthyl-Chalcone (D14) for osteosarcoma
(MDPI, 2021-08-06)
Chalcones (1,3-diaryl-2-propen-1-ones) are naturally occurring polyphenols with known anticancer activity against a variety of tumor cell lines, including osteosarcoma (OS). In this paper, we present the preparation and ...
Antimicrobial active bioplastics using triangular silver nano-plate integrated polycaprolactone and polylactic acid films
(MDPI, 2021-02-28)
An innovative antimicrobial technology for plastic surfaces is presented. We report the
synthesis and scale-up of triangular silver nano-plates (TSNPs) and their integration into polycaprolactone
(PCL) and polylactic ...
Synthesis and characterisation of novel temperature and pH sensitive physically crosslinked poly(N-vinylcaprolactam-co-itaconic acid) hydrogels for drug delivery.
(MDPI, 2019-08-29)
Previous studies involving poly N-vinylcaprolactam (PNVCL) and itaconic acid (IA) have synthesised the hydrogels with the presence of a solvent and a crosslinker, producing chemically crosslinked hydrogel systems. In this ...
Bioactive composites fabricated by freezing-thawing method for bone regeneration applications.
(Wiley, 2016-04)
Hydrogels are widely used for controlled delivery of therapeutic agents. However, hydrogels lack bioactivity to encourage bone formation and mechanical integrity. Moreover, chemically crosslinked hydrogels exhibit cytotoxic ...
Nano-enhanced food contanct materials and the in vitro toxicity to human intestinal cells of nano-ZnO at low dose.
(IOP Science, 2011)
Nano Zinc Oxide (nZnO) has been shown to display antimicrobial effects which have lead to its application in a number of areas such as antimicrobial surface coatings, anti bacterial wound dressings and more recently in ...
Development of novel monolithic matrices for drug delivery using conventional and non-conventional polymer processing technologies.
(2007)
The aim of this study was to produce a range of polymer based monolithic matrices
for controlled oral drug delivery using conventional polymer processing equipment. Poly
(ethylene oxide) (PEO) was chosen as the primary ...
The development of advanced smart polymer formulations for potential biomedical applications.
(Athlone Institute of Technology, 2020-10)
In the past twenty years, a theme in the pharmaceutical industry is to move towards more efficient use of active pharmaceutical ingredients and the need for improved delivery systems. Smart polymers throughout the literature ...
A novel manufacturing technique for the production of tailored solid dosage forms
(Athlone Institute of Technology, 2020)
The main objective of this study was to evaluate manufacturing processes for the fabrication of tailored solid dosage forms. Two hot-melt extrusion based manufacturing processes were investigated, a 3D printing process ...
A quality of experience evaluation of augmented reality and haptic feedback in a low-cost gait analysis system
(Athlone Institute of Technology, 2020-06)
Gait analysis is a technique that is used to understand movement patterns and, in some cases, to inform the development of rehabilitation protocols. Traditional rehabilitation approaches have relied on expert guided feedback ...
Development of drug eluting biodegradable nanocomposite for use in coronary stents
(Athlone Institute of Technology, 2021-07)
Coronary stents are the scaffolds placed inside the blocked arteries, which aids the restoration of the passage of blood to the heart. Coronary stenting has become a standard medical procedure to treat coronary heart disease ...