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Synthesis, characterization and monoamine transporter activity of the new psychoactive substance 3’,4’-methylenedioxy-4-methylaminorex (MDMAR).
(Wiley, 2015-07)
The recent occurrence of deaths associated with the psychostimulant cis-4,4'-dimethylaminorex (4,4'-DMAR) in Europe indicated the presence of a newly emerged psychoactive substance on the market. Subsequently, the existence ...
Test purchase, synthesis and characterization of 2- methoxydiphenidine (MXP) and differentiation from its metaand para-substituted isomers.
(Wiley, 2015-09)
The structurally diverse nature of the 1,2-diphenylethylamine template provides
access to a range of substances for drug discovery work but some have attracted
attention as ‘research chemicals’. The most recent examples ...
Analytical characterization and pharmacological evaluation of the new psychoactive substance 4-fluoromethylphenidate (4F-MPH) and differentiation between the (±)-threo- and (±)-erythro- diastereomers
(Wiley, 2017-03)
Misuse of (±)-threo-methylphenidate (methyl-2-phenyl-2-(piperidin-2-yl)acetate; Ritalin®; MPH) has long been acknowledged, but the appearance of MPH analogs in the form of 'research chemicals' has only emerged in more ...
The synthesis and characterization of the ‘research chemical’ N-(1- amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl) -1H-pyrazole-5-carboxamide (3,5-AB-CHMFUPPYCA) and differentiation from its 5,3-regioisomer.
(Wiley, 2016-09)
This study presents the identification of N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-
(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide that was termed
3,5-AB-CHMFUPPYCA. This compound was obtained from a ...
Test purchase, synthesis and characterization of 3-fluorophenmetrazine (3-FPM) and differentiation from its ortho- and para-substituted isomers
(Wiley, 2017-03)
The knowledge captured in patent and scientific research literature stimulates
new ideas and fosters new drug development efforts. Manufacturers and
entrepreneurs dedicated to the sale of ‘research chemicals’ and/or ...
An investigation into the effects of pH and material concentrations on the morphology of Chitosan-Alginate microspheres prepared using an Ionic Gelation technique.
(IJASRM, 2017-10)
The aim of this study was to develop microspheres as
a drug delivery system using natural polymeric
materials including Alginate and Chitosan using an
Ionotropic Gelation method of synthesis. In this
study, several ...
Synthesis, characterization and monoamine transporter activity of the new psychoactive substance mexedrone and its N-methoxy positional isomer, N-methoxymephedrone.
(Wiley, 2017-03)
3-Methoxy-2-(methylamino)-1-(4-methylphenyl)propan-1-one (mexedrone)
appeared in 2015 and was advertised by UK Internet retailers as a noncontrolled
mephedrone derivative (2-(methylamino)-1-(4-
methylphenyl)propan-1-one), ...
Preparation and characterization of the ‘research chemical’ diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers.
(Wiley, 2015-05)
Substances with the diphenylethylamine nucleus represent a recent addition to the
product catalog of dissociative agents sold as research chemicals on the Internet.
Diphenidine, i.e. 1-(1,2-diphenylethyl)piperidine ...
Synthesis, analytical characterization and monoamine transporter activity of the new psychoactive substance 4- methylphenmetrazine (4-MPM), with differentiation from its ortho- and meta- positional isomers
(Wiley, 2018-09)
The availability of new psychoactive substances on the recreational drug
market continues to create challenges for scientists in the forensic, clinical
and toxicology fields. Phenmetrazine (3-methyl-2-phenylmorpholine) ...
Development of Amoxicillin loaded microspheres for anti-Helicobacter pylori infection using Ionic Gelation method
(IJASRM, 2017-11)
The aim of this project was to develop microspheres loaded with Amoxicillin for anti-Helicobacter pylori infection. Amoxicillin loaded microspheres were developed using blends of natural polymers such as Alginate and ...