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    Mucoadhesive bilayer vaginal tablet as a potential treatment for cervical cancer 

    Abidin, Ismin Izwani Zainol; Murphy, Emma J.; Rezoagli, Emanuele; Major, Ian (Athlone Institute of Technology, 2020-06)
    Cervical cancer is a cancer of the cells of the cervice. It is the 2nd most common cancer affecting women. >270,000 die from it annually. >5000,000 women worldwide are diagnosed.
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    A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix 

    Abidin, Ismin Zainol; Rezoagli, Emanuele; Simonassi-Paiva, Bianca; Fehrenbach, Gustavo Waltzer; Masterson, Kevin; Pogue, Robert; Cao, Zhi; Rowan, Neil; Murphy, Emma J.; Major, Ian (MDPI, 2020-12-06)
    This study was performed to develop an adjuvant therapy in the form of a self-administered vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to reduce relapse by eradicating ...
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    Vaginal drug delivery for the localised treatment of cervical cancer. 

    Major, Ian; McConville, Christopher (Springer, 2017-06-08)
    Cervical cancer is usually treated by surgery, with the more advanced cancers requiring adjuvant chemotherapy or radiotherapy. The location of the cervix makes it easily accessible through the vagina for the localised ...

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    Major, Ian (3)
    Murphy, Emma J. (2)Rezoagli, Emanuele (2)Abidin, Ismin Izwani Zainol (1)Abidin, Ismin Zainol (1)Cao, Zhi (1)Fehrenbach, Gustavo Waltzer (1)Masterson, Kevin (1)McConville, Christopher (1)Pogue, Robert (1)... View MoreSubjectCervical cancer (3)
    Vaginal drug delivery (3)
    Materials Research Institute AIT (2)Bilayer tablets (1)Chitosan (1)Combination therapy (1)Drug synergism (1)Fertility sparing surgery (1)Localised drug delivery (1)Mucoadhesion (1)... View MoreDate Issued2020 (2)2017 (1)Has File(s)
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