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β-glucan metabolic and immunomodulatory properties and potential for clinical application
(MDPI, 2020-12-10)
β-glucans are complex polysaccharides that are found in several plants and foods, including mushrooms. β-glucans display an array of potentially therapeutic properties. β-glucans have metabolic and gastro-intestinal effects, ...
β-Glucan
(MDPI, 2021)
β-glucans are a key active ingredient in mushrooms and are also found in oats, barley, yeast, bacteria and algae. In microbial sources, they are a structural component and in grain sources, they are found in the endospermic ...
Immunomodulatory activity of β-glucan polysaccharides isolated from different species of mushroom – A potential treatment for inflammatory lung conditions
(Elsevier, 2022-02-25)
Acute respiratory distress syndrome (ARDS) is the most common form of acute severe hypoxemic respiratory failure in the critically ill with a hospital mortality of 40%. Alveolar inflammation is one of the hallmarks for ...
Mucoadhesive bilayer vaginal tablet as a potential treatment for cervical cancer
(Athlone Institute of Technology, 2020-06)
Cervical cancer is a cancer of the cells of the cervice. It is the 2nd most common cancer affecting women. >270,000 die from it annually. >5000,000 women worldwide are diagnosed.
A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix
(MDPI, 2020-12-06)
This study was performed to develop an adjuvant therapy in the form of a self-administered
vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to
reduce relapse by eradicating ...
β-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in-vitro immunomodulatory and pulmonary cytoprotective effects — Implications for coronavirus disease (COVID-19) immunotherapies.
(Elsevier, 2020-05-11)
Coronavirus pneumonia is accompanied by rapid virus replication, where a large number of inflammatory cell infiltration and cytokine storm may lead to acute lung injury, acute respiratory distress syndrome (ARDS) and death. ...
A systematic review of mucoadhesive vaginal tablet testing
(AboutScience, 2023-01-16)
Drug administration through the vaginal tract is one of the oldest modalities of pharmacotherapy, and it is also one of the most explored. Since the vaginal cavity has a wide surface area, a plentiful blood supply, and a ...