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The influence of low shear microbore extrusion on the properties of high molecular weight poly(l-lactic acid) for medical tubing applications.
(MDPI, 2019-04)
Biodegradable polymers play a crucial role in the medical device field, with a broad range
of applications such as suturing, drug delivery, tissue engineering, sca olding, orthopaedics, and
fixation devices. Poly-l-lactic ...
Influence of annealing and biaxial expansion on the properties of Poly-l-lactic) medical tubing.
(MDPI, 2019-07-11)
Poly-l-lactic acid (PLLA) is one of the most common bioabsorbable materials in the medical
device field. However, its use in load-bearing applications is limited due to its inferior mechanical
properties when compared ...
The development of a melt-extruded shellac carrier for the targeted delivery of probiotics to the colon.
(MDPI, 2017-12)
Hot melt extrusion (HME) is considered an efficient technique in developing solid molecular
dispersions, and has been demonstrated to provide sustained, modified and targeted drug delivery
resulting in improved ...
Mechanical properties of anodic titanium films containing ions of Ca and P submitted to heat and hydrothermal treatment.
(Elsevier, 2016-12)
Anodic oxidation is a technique widely used to improve the bioactivity of Ti surface. In this study, micro-arc oxidation (MAO) was used to obtain an anodic film incorporating Ca and P ions to evaluate the effect of heat ...
Smart hydrogels: therapeutic advancements in hydrogel technology for smart drug delivery applications.
(Wiley, 2015-12)
Hydrogels are a fusion of solid and liquid phases which closely mimic biological tissue. As such they have enormous potential for drug delivery systems as they are biocompatible and may be tailored to specific applications. ...
Pathogen displacement during intermittent catheter insertion: a novel in vitro urethra model.
(Wiley, 2019-11-29)
Aim: To develop a novel in vitro urethra model and use it to determine if insertion of an intermittent urinary catheter (IC) displaces pathogenic bacteria from the urethral meatus along the urethra. Methods: Displacement ...
Additive manufacturing of personalized pharmaceutical dosage forms via stereolithography.
(MDPI, 2019-12-03)
The introduction of three-dimensional printing (3DP) has created exciting possibilities for
the fabrication of dosage forms, paving the way for personalized medicine. In this study, oral dosage
forms of two drug ...
Material considerations for fused-filament fabrication of solid dosage forms.
(MDPI, 2018-04-02)
Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, ...
Degradable nanocomposites for fused filament fabrication applications.
(MDPI, 2018-05-09)
There has been a substantial increase in the use and development of plastics over the
last century. However, due to ever-diminishing petroleum feedstocks and growing concern for the
environment, there has been a rise in ...
Optimizing the hardness of SLA printed objects by using the neural netwok and genetic algorithm
(Elsevier, 2019-06)
In the developing field of manufacturing, 3D printing is rapidly increasing the horizon of what is possible. However, the possibility of implementing new 3D methods of production has brought new challenges for industries, ...