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Modification of hyaluronic acid for stereolithography 3D printing of hydrogel nerve conduits
(Athlone Institute of Technology, 2020-06)
The peripheral nervous system transmits signals from the brain to the limbs and organs of the
body. Peripheral nerve injuries (PNIs) resulting from trauma, illness or cancer affect
approximately 1 million people in Europe ...
β-glucan metabolic and immunomodulatory properties and potential for clinical application
(MDPI, 2020-12-10)
β-glucans are complex polysaccharides that are found in several plants and foods, including mushrooms. β-glucans display an array of potentially therapeutic properties. β-glucans have metabolic and gastro-intestinal effects, ...
Hybrid manufacturing 3D printing and injection moulding in the pursuit of mass customization
(Athlone Institute of Technology, 2020-06)
Project Overview:
Mass customization is a marketing and manufacturing technique which combines the flexibility and personalization of custom-made products with the low unit costs associated with mass production. The ...
Effect of stereolithography 3D printing on the properties of PEGDMA hydrogels.
(MDPI, 2020-09-03)
Stereolithography (SLA)-based 3D printing has proven to have several advantages over
traditional fabrication techniques as it allows for the control of hydrogel synthesis at a very high
resolution, making possible the ...
Mucoadhesive bilayer vaginal tablet as a potential treatment for cervical cancer
(Athlone Institute of Technology, 2020-06)
Cervical cancer is a cancer of the cells of the cervice. It is the 2nd most common cancer affecting women. >270,000 die from it annually. >5000,000 women worldwide are diagnosed.
A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix
(MDPI, 2020-12-06)
This study was performed to develop an adjuvant therapy in the form of a self-administered
vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to
reduce relapse by eradicating ...
Purified β‐glucans from the Shiitake mushroom ameliorates antibiotic‐resistant Klebsiella pneumoniae‐induced pulmonary sepsis
(Society for Applied Microbiology, 2020-07-24)
Bacterial infection remains the main cause of acute respiratory distress syndrome and is a leading cause of death and disability in critically ill patients. Here we report on the use of purified β‐glucan (lentinan) extracts ...
Fused-filament fabrication of PEEK: a review of process-structure-property relationships.
(MDPI, 2020-07-27)
Poly (ether ether ketone) (PEEK) is a high-performance engineering thermoplastic polymer
with potential for use in a variety of metal replacement applications due to its high strength to weight
ratio. This combination ...
β-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in-vitro immunomodulatory and pulmonary cytoprotective effects — Implications for coronavirus disease (COVID-19) immunotherapies.
(Elsevier, 2020-05-11)
Coronavirus pneumonia is accompanied by rapid virus replication, where a large number of inflammatory cell infiltration and cytokine storm may lead to acute lung injury, acute respiratory distress syndrome (ARDS) and death. ...