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Degradable polymer nanocomposites for fused filament fabrication applications
(Athlone Institute of Technology, 2018-04-24)
The use of plastics in everyday life has increased dramatically during the course of the 20th and 21st century which is primarily due to the characteristics plastics offer in the development of new products to meet the ...
The influence of mechanical stretching and freeze-thaw processing on the properties of polyvinyl alcohol hydrogels for drug delivery applications
(Athlone Institute of Technology, 2018-04-24)
The study describes the development of physically cross-linked polyvinyl alcohol (PVA) hydrogels using uniaxial orientation via freeze-thawing (F/T). Although cryogels have shown significant improvements in long-term ...
Development of high strength nanocomposite for biodegradable stents
(Athlone Institute of Technology, 2018-04-24)
The use of biodegradable polymer materials are considered to be good alternatives in urology (Donohue et. al. 2018), cardiovascular (Brie et. al. 2016) and tracheal airway stenosis which provide support before it is absorbed ...
Enhancing the bioavailability of hydrophobic drugs using hot melt extrusion
(Athlone Institute of Technology, 2018-04-24)
Many existing drugs (as well as new revelations) in the pharmaceutical industry bear a distinct disadvantage in the sense that they are not water soluble, displaying low bioavailability values and consequently a reduced ...
3D printed end of arm tooling (EOAT) of a robotic arm
(Athlone Institute of Technology, 2018-04-24)
This research furthers the practice of designing and manufacturing an EOAT for low weight applications by utilising additive manufacturing (“3D Printing”) techniques to decrease energy consumption via tool weight savings ...
Stability studies of hot-melt extruded ternary solid dispersions of poorly-water soluble Indomethacin with Poly(vinyl pyrrolidone-co-vinyl acetate) and polyethylene oxide.
(Elsevier, 2019-08)
This investigation aims to evaluate the effect of moisture and temperature on the physical
stability and dissolution behaviour of hot-melt extruded binary and plasticised ternary solid
dispersions. Poorly water-soluble ...
Analysis of the mechanical properties of solvent cast blends of PLA/PCL.
(Trans Tech Publications, 2014-09)
Polylactic acid (PLA) is the most promising material in the biodegradable category. However, brittleness and poor thermal stability restrict its application. To overcome this limitation, PLA may be blended with other ...
Orthopaedic 3D printing in orthopaedic medicine.
(Springer, 2019-09-17)
Orthopaedic surgeries are commonly extremely challenging, and innovations are required to overcome a series of recognised difficulties and improve patient outcomes. Complications, in particular, the high occurrence of ...
Green synthesis of zinc oxide nanoparticles: a review of the synthesis methodology and mechanism of formation.
(Elsevier, 2020-03)
Zinc oxide is of significant importance for many industries due to its versatile properties, which have been enhanced with the production of this material in the nanoscale. Nonetheless, the increase in concerns related to ...
Comparison of fused-filament fabrication to direct compression and injection molding in the manufacture of oral tablets.
(Elsevier, 2019-03-10)
Oral tablets are a convenient form to deliver active pharmaceutical ingredients (API) and have a high level of acceptance from clinicians and patients. There is a wide range of excipients available for the fabrication of ...