Search
Now showing items 1-5 of 5
Effect of thermal annealing on a bilayer polyvinyl alcohol/polyacrylic acid electrospun hydrogel nanofibres loaded with doxorubicin and clarithromycin for a synergism effect against osteosarcoma cells
(Elsevier, 2021-08-02)
Polyvinyl alcohol/polyacrylic acid (PVA/PAA) bilayer hydrogel nanofibres were successfully fabricated by
electrospinning and physically crosslinked via heat treatment. The effects of the thermal annealing
process on the ...
Treatment for the amelioration of persistent factors in complex anal fistula
(Springer, 2021-11-19)
Anal fistulae are abnormal hollow connections between the wall of the anal canal and the
perianal skin around the anus that have remained a burden on the medical sector for centuries.
The complexity of this disease is ...
Production and testing of the flat faced tablets via overpriting of injection moulded tablet bases
(Athlone Institute of Technology, 2020-06)
The pharmaceutical industry is exploring the realization of tailored dosage forms for individual patients to provide precision medicine. My supervisors have previously used a hybrid manufacturing technique that overmoulded ...
"My heart, your heart"; hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded drug delivery system
(Athlone Institute of Technology, 2020-06)
Cardiovascular diseases (CVDs) are the number 1 cause
of death globally. Fenofibrate has been shown an
excellent treating effect on CVDs. However, Fenofibrate
is a neutral, lipophilic compound that is practically
insoluble ...
Synthesis and characterisation of novel temperature and pH sensitive physically crosslinked poly(N-vinylcaprolactam-co-itaconic acid) hydrogels for drug delivery.
(MDPI, 2019-08-29)
Previous studies involving poly N-vinylcaprolactam (PNVCL) and itaconic acid (IA) have synthesised the hydrogels with the presence of a solvent and a crosslinker, producing chemically crosslinked hydrogel systems. In this ...