Now showing items 1-3 of 3

    • A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix 

      Abidin, Ismin Zainol; Rezoagli, Emanuele; Simonassi-Paiva, Bianca; Fehrenbach, Gustavo Waltzer; Masterson, Kevin; Pogue, Robert; Cao, Zhi; Rowan, Neil; Murphy, Emma J.; Major, Ian (MDPI, 2020-12-06)
      This study was performed to develop an adjuvant therapy in the form of a self-administered vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to reduce relapse by eradicating ...
    • Mucoadhesive bilayer vaginal tablet as a potential treatment for cervical cancer 

      Abidin, Ismin Izwani Zainol; Murphy, Emma J.; Rezoagli, Emanuele; Major, Ian (Athlone Institute of Technology, 2020-06)
      Cervical cancer is a cancer of the cells of the cervice. It is the 2nd most common cancer affecting women. >270,000 die from it annually. >5000,000 women worldwide are diagnosed.
    • Vaginal drug delivery for the localised treatment of cervical cancer. 

      Major, Ian; McConville, Christopher (Springer, 2017-06-08)
      Cervical cancer is usually treated by surgery, with the more advanced cancers requiring adjuvant chemotherapy or radiotherapy. The location of the cervix makes it easily accessible through the vagina for the localised ...