Browsing Technological University of the Shannon: Midlands Midwest by Subject "Materials Research Institute - AIT"
Now showing items 1-20 of 28
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3D printed polymers are less stable than injection moulded counterparts when exposed to terminal sterilization processes using novel vaporized hydrogen peroxide and electron beam processes.
(Elsevier, 2019-11-21)There is an increasing trend for use of 3D printing processes in healthcare due in part to emergence of customised medical devices and associated low manufacturing cost. However, there is a dearth of knowledge on the ... -
Additive manufacturing of personalized pharmaceutical dosage forms via stereolithography.
(MDPI, 2019-12-03)The introduction of three-dimensional printing (3DP) has created exciting possibilities for the fabrication of dosage forms, paving the way for personalized medicine. In this study, oral dosage forms of two drug ... -
Additive manufacturing of PLA/HNT nanocomposites for biomedical applications
(Elsevier, 2019)Additive manufacturing has been of great interest of research in various applications due to their ease in processability, cost effectiveness and adaptability. In this study Poly Lactic Acid (PLA) was used as the base ... -
Composite films of thermoplastic starch and CaC12 extracted from eggshells for extendiing food shelf-life
(MDPI, 2021-09-03)Calcium chloride (CaCl2) has been widely used to maintain the quality of fresh-cut fruits and vegetables because it stabilizes and strengthens the membrane system against fungal attacks. It is mainly applied via spray ... -
Degradable nanocomposites for fused filament fabrication applications.
(MDPI, 2018-05-09)There has been a substantial increase in the use and development of plastics over the last century. However, due to ever-diminishing petroleum feedstocks and growing concern for the environment, there has been a rise in ... -
The development of a melt-extruded shellac carrier for the targeted delivery of probiotics to the colon.
(MDPI, 2017-12)Hot melt extrusion (HME) is considered an efficient technique in developing solid molecular dispersions, and has been demonstrated to provide sustained, modified and targeted drug delivery resulting in improved ... -
Development of a new bone scaffold for the treatment of large bone defects
(Athlone Institute of Technology, 2020-06)Large bone defects are typically caused by incidents such as fractures, diseases, trauma or surgeries. Worldwide more that 3/5 million bone grafts (either autografts or allografts) are performed each year. -
Development of novel polyethylene glycol dimethacrylate (PEGDMA)-based hydrogels for never regeneration
(Athlone Institute of Technology, 2020-06)Injury to the peripheral nervous system (PNS) affects more than 1,000,000 people worlwide a year. It is estimated that $150 billion is spent on nerve injury repair in the USA alone each year. The current surgical methods ... -
Development of smart 4-D materials utilising novel self assembly polymers
(2020-06)4D printing is a technique that uses a 3 D printer to create objects that change their shape overtime 4 D printing involves the use of smart materials that will transform when exposed to an external stimuli These can ... -
The effect of cooling on the degree of crystallinity, solid-state properties, and dissolution rate of multi-component hot-melt extruded solid dispersions.
(MDPI, 2020-03-01)The effect of cooling on the degree of crystallinity, solid-state and dissolution properties of multi-component hot-melt extruded solid dispersions [SD] is of great interest for the successful formulation of amorphous ... -
Evaluation of the efficacy of lipid core nanoemulsions containing temozolomide coupled to ferrocenes in the treatment of Glioblastomas
(Athlone Institute of Technology, 2020)Glioblastoma (GB) is the most common and aggressive neoplastic brain tumor, and its treatment has proved to be a challenge. For decades its therapy has been based on the use of temozolomide (TMZ), but the survival rate ... -
Influence of annealing and biaxial expansion on the properties of Poly-l-lactic) medical tubing.
(MDPI, 2019-07-11)Poly-l-lactic acid (PLLA) is one of the most common bioabsorbable materials in the medical device field. However, its use in load-bearing applications is limited due to its inferior mechanical properties when compared ... -
The influence of low shear microbore extrusion on the properties of high molecular weight poly(l-lactic acid) for medical tubing applications.
(MDPI, 2019-04)Biodegradable polymers play a crucial role in the medical device field, with a broad range of applications such as suturing, drug delivery, tissue engineering, sca olding, orthopaedics, and fixation devices. Poly-l-lactic ... -
An investigation of the inter-molecular interaction, solid-state properties and dissolution properties of mixed Copovidone hot-melt extruded solid dispersions.
(Elsevier, 2019-10)Previous research has focused on spray dried quaternary mixtures which due to the addition of a surfactant 26 affected the physical stability and amorphous stability of selected model drugs. Very little research has 27 ... -
Material considerations for fused-filament fabrication of solid dosage forms.
(MDPI, 2018-04-02)Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, ... -
Mechanical properties of anodic titanium films containing ions of Ca and P submitted to heat and hydrothermal treatment.
(Elsevier, 2016-12)Anodic oxidation is a technique widely used to improve the bioactivity of Ti surface. In this study, micro-arc oxidation (MAO) was used to obtain an anodic film incorporating Ca and P ions to evaluate the effect of heat ... -
Microfibrillated cellulose films containing chitosan and tannic acid for wound healing applications
(Springer, 2021-06-12)The effectiveness of tannic acid as antimicrobial and wound healing for burns have been shown for a century; however, uncontrolled target dosage may result in undesirable side-effects. Remarkably, tannic acid polyphenols ... -
Nanofillers can be used to enhance the thermal conductivity of commercially available SLA resins.
(Elsevier, 2019-06)Stereolithography (SLA) is a form of 3D printing technology used for the production parts and patterns in a layer by layer fashion. Traditionally, 3D printing has been used for the manufacture of prototypes, however it is ... -
Optimizing the hardness of SLA printed objects by using the neural netwok and genetic algorithm
(Elsevier, 2019-06)In the developing field of manufacturing, 3D printing is rapidly increasing the horizon of what is possible. However, the possibility of implementing new 3D methods of production has brought new challenges for industries, ... -
Pathogen displacement during intermittent catheter insertion: a novel in vitro urethra model.
(Wiley, 2019-11-29)Aim: To develop a novel in vitro urethra model and use it to determine if insertion of an intermittent urinary catheter (IC) displaces pathogenic bacteria from the urethral meatus along the urethra. Methods: Displacement ...