Browsing Technological University of the Shannon: Midlands Midwest by Author "de Lima, Gabriel Goetten"
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Antioxidant, antibacterial and antitumoral activities of kraft lignin from hardwood factionated by acid precipitation
Lourençon, Tainise V.; de Lima, Gabriel Goetten; Ribeiro, Carolina S.; Hansel, Fabricio A.; Maciel, Giselle M.; da Silva, Krisle; Winnischofer, Sheila M.B.; de Muniz, Graciela I.B.; Magalhães, Washington L.E. (Elsevier, 2020-11-10)Kraft lignin, so far useful for energy generation, has been gathering considerable attention as an alternative material to replace fossil-based resources mainly due to its high phenolic content. However, the wide molecular ... -
Bioactive composites fabricated by freezing-thawing method for bone regeneration applications.
Canillas, Maria; de Lima, Gabriel Goetten; Rodríguez, Miguel A.; Nugent, Michael J.D.; Devine, Declan M. (Wiley, 2016-04)Hydrogels are widely used for controlled delivery of therapeutic agents. However, hydrogels lack bioactivity to encourage bone formation and mechanical integrity. Moreover, chemically crosslinked hydrogels exhibit cytotoxic ... -
Characterisation and in vivo evaluation of Araucaria angustifolia pinhão seed coat nanosuspension as a functional food source
de Lima, Gabriel Goetten; de Miranda, Neli Branco; Timm, Thaynã Gonçalves; Matos, Mailson; Magalhães, Washington Luiz Esteves; Tavares, Lorena Benathar Ballod; Hansel, Fabricio Augusto; Helm, Cristiane Vieira (Royal Society of Chemistry, 2020-10-08)Araucaria angustifolia seeds are culturally important from South America; however, the seed coat is generally discarded and have yet to find a beneficial commercial impact. We propose a new formulation to the usage of ... -
Characterization of gels and films produced from Pinhão seed coat nanocellulose as a potential use for wound healing dressings and screening of Its compounds towards antitumour effects
de Lima, Tielidy A. de M.; de Lima, Gabriel Goetten; Chee, Bor Shin; Henn, Jeferson G.; Cortese, Yvonne J.; Matos, Mailson; Helm, Cristiane V.; Magalhães, Washington L.E.; Nugent, Michael J.D. (MDPI, 2022-07-07)The reuse of agro-industrial waste assumes great importance today. Pinhão is the seed of Araucaria angustifolia, which is native to the mountains of southern Brazil, Paraguay, and Argentina. The coat is a by-product of ... -
Composite cryogels for dual drug delivery and enhanced mechanical properties.
de Lima, Gabriel Goetten; Traon, Fanny; Moal, Eloan; Canillas, Maria; Dunne, Nicholas; Devine, Declan M.; Nugent, Michael D. (Wiley, 2018-04)In this study, we present a simple and effective process that integrates hydrogels with drugs + ceramics via physical crosslinks resulting in improved mechanical properties. These cryogels have the potential for controlled ... -
Development of alginate beads with encapsulated jabuticaba peel and propolis extracts to achieve a new natural colorant antioxidant additive.
Dallabona, Ithiara Dalponte; de Lima, Gabriel Goetten; Cestaro, Beatriz Isabella; Tasso, Ivisson de Souza; Paiva, Thainnane Silva; Laureanti, Emanuele Joana Gbur; Jorge, Luiz Mario de Matos; da Silva, Bruno José Gonçalves; Helm, Cristiane Vieira; Mathias, Alvaro Luiz; Jorge, Regina Maria Matos (Elsevier, 2020-07)This work aims to encapsulate anthocyanins and phenolic compounds extracted from a native Brazilian fruit peel - jabuticaba (Plinia cauliflora (Mart.) Kausel) and propolis from Tubuna (Scaptotrigona bipunctata) stingless ... -
Development, characterization and cell viability inhibition of PVA spheres loaded with Doxorubicin and 4′-Amino-1-Naphthyl-Chalcone (D14) for osteosarcoma
Seba, Viviane; de Lima, Gabriel Goetten; Periera, Bruno Leandro; Silva, Gabriel; Reinhardt, Luiza Steffens; Arantes, Pablo Ricardo; Shee, Bor Shin; dos Santos, Maria Bastos; França, Suzelei C.; Regasini, Luis Octavio; Fachin, Ana Lúcia; Cao, Zhi; Nugent, Michael J.D.; Marins, Mozart (MDPI, 2021-08-06)Chalcones (1,3-diaryl-2-propen-1-ones) are naturally occurring polyphenols with known anticancer activity against a variety of tumor cell lines, including osteosarcoma (OS). In this paper, we present the preparation and ... -
Effect of anodizing time on the mechanical properties of porous titania coatings formed by micro-arc oxidation.
Santos Jr., Emanuel; de Souza, Gelson B.; Serbena, Francisco C.; Santos, Henrique L.; de Lima, Gabriel Goetten; Szesz, Eduardo M.; Kuromoto, Neide K. (Elsevier, 2017-01-15)Porous TiO2 coatings were produced on commercially pure Ti substrates by micro-arc oxidation (MAO) in 1.0 M H2SO4 electrolyte for different anodizing times. Their mechanical properties were assessed by means of instrumented ... -
Effect of cullulose size-concentration on the structure of polyvinyl alcohol hydrogels.
de Lima, Gabriel Goetten; Ferreira, Bruno; Matos, Mailson; Pereira, Bruno Leandro; Nugent, Michael J.D.; Hansel, Fabríco Augusto; Magalhães, Washington Luiz Esteves (Elsevier, 2020-06-11)Microfibrillated cellulose as a reinforcement agent has been investigated extensively due to their unique characteristics, which can reorder the structure of polymers and hydrogels leading to improved mechanical properties ... -
Effect of thermal annealing on a bilayer polyvinyl alcohol/polyacrylic acid electrospun hydrogel nanofibres loaded with doxorubicin and clarithromycin for a synergism effect against osteosarcoma cells
Chee, Bor Shin; de Lima, Gabriel Goetten; de Lima, T.A.M.; Seba, Viviane; Lemarquis, C.; Pereira, Bruno Leandro; Bandeira, Marina; Cao, Zhi; Nugent, Michael J.D. (Elsevier, 2021-08-02)Polyvinyl alcohol/polyacrylic acid (PVA/PAA) bilayer hydrogel nanofibres were successfully fabricated by electrospinning and physically crosslinked via heat treatment. The effects of the thermal annealing process on the ... -
Effect of unidirectional freezing using a thermal camera on polyvinyl (alchohol) for aligned porous cyrogels.
de Lima, Gabriel Goetten; Barbosa, Rêydila Rayenne Caminhas; de Andrade Santos, M.P.; Chee, Bor Shin; Esteves Magalhães, Washington Luiz Esteves; Devine, Declan M.; Nugent, Michael J.D. (Taylor & Francis Online, 2020-03-18)Unidirectional freeze casting for polymers and ceramics has been performed extensively; however, the mechanisms involved in unidirectional freezing are not thoroughly understood and therefore, in this study, polyvinyl ... -
Electrospinning of hydrogels for biomedical applications
de Lima, Gabriel Goetten; Lyons, Sean; Devine, Declan M.; Nugent, Michael J.D. (Springer Nature, 2018)The field of biomedical applications for hydrogels requires the development of nanostructures with specific controlled diameter and mechanical properties. Nanofibers are ideally candidates for these advanced requirements, ... -
Electrospun hydrogels composites for bone tissue engineering.
Chee, Bor Shin; de Lima, Gabriel Goetten; Devine, Declan; Nugent, Michael J. D. (Woodhead Publishing, 2019)Electrospinning is one of the foremost nanotechnology applications to fabricate bone tissue engineering scaffolds with sizes in the nanometer range. It is regarded as a versatile, inexpensive, and relatively simple methodology ... -
Enzymatic activities and analysis of a mycelium-based composite formation using peach palm (Bactris gasipaes) residues on Lentinula edodes.
de Lima, Gabriel Goetten; Schoenherr, Zaira; Magalhães, Washington; Tavares, Lorena; Helm, Cristiane (Research Square, 2020-08-03)By seeding fungus on top of industry residues, a mycelium can grow and form a compacted network structure, producing a material whose properties can be quite similar to polystyrene. However, depending on the source used, ... -
The evaluation of the potential ecotoxicity of pyroligenous acid obtained from fast pyrolsis.
de Lima, Gabriel Goetten; Mendes, Camila; de Marchi, Gustavo; Vicari, Taynah; Cestari, Marta Margarete; Gomes, Monike F.; Ramsdorf, Wanessa Algarte; Magalhães, Washington Luiz Esteves; Hansel, Fabricio Augusto; Morais, Daniela Leme (Elsevier, 2019-09-30)Pyroligneous acid (PA) is a by-product of bio-oil, which is obtained by pyrolysis of the wood. This product has been tested for use in several areas, such as agriculture, as a promising green herbicide; however, there are ... -
Extraction method plays critical role in antibacterial activity of propolis loaded hydrogels.
de Lima, Gabriel Goetten; de Souza, Ronaldo O,; Bozzi, Aline; Poplawska, Malgorzata A.; Devine, Declan M.; Nugent, Michael J. D. (Elsevier, 2016-03)Extracted propolis has been used for a long time as a remedy. However, if the release rate of propolis is not controlled, the efficacy is reduced. To overcome this issue, extracted propolis was added to a cryogel system. ... -
Injectable bone substitute based on chitosan with polyethylene glycol polymeric solution and biphasic calcium phosphate microspheres.
Lima, Daniel Bezerra; de Souza, Mônica Adriana Araújo; de Lima, Gabriel Goetten; Souto, Erick Platiní Ferreira; Oliveira, Hugo Miguel Lisboa; Fook, Marcus Vinícius Lia; de Sá, Marcelo Joge Cavalcanti (Elsevier, 2020-06-10)We described a method to produce an injectable bone substitute consisting of a solid and liquid phase, this solid was formed using the coacervation method consisting of a mixture of Hydroxyapatite (HAp) and beta-Tricalcium ... -
Investigation of the effects of orientation on freeze/thawed Polyvinyl alcohol hydrogel properties.
Chee, Bor Shin; de Lima, Gabriel Goetten; Devine, Declan M.; Nugent, Michael J. D. (Elsevier, 2018-12)Although hydrogels produced via freeze-thawing (F/T) technique have been thoroughly studied in literature, stretching hydrogels in between freeze-thawing cycles could change its properties and might be modulated for drug ... -
Mechanical properties of anodic titanium films containing ions of Ca and P submitted to heat and hydrothermal treatment.
de Lima, Gabriel Goetten; de Souza, Gelson B.; Lepienski, Carlos M.; Kuromoto, Neide K. (Elsevier, 2016-12)Anodic oxidation is a technique widely used to improve the bioactivity of Ti surface. In this study, micro-arc oxidation (MAO) was used to obtain an anodic film incorporating Ca and P ions to evaluate the effect of heat ... -
Microfibrillated cellulose films containing chitosan and tannic acid for wound healing applications
Alibadi, Meysam; Chee, Bor Shin; Matos, Mailson; Cortese, Yvonne J.; Nugent, Michael J.D.; de Lima, Tieilidy A. M.; Magalhães, Washingtonn L.E.; de Lima, Gabriel Goetten; Firouzabadi, Mohammadreza Dehghani (Springer, 2021-06-12)The effectiveness of tannic acid as antimicrobial and wound healing for burns have been shown for a century; however, uncontrolled target dosage may result in undesirable side-effects. Remarkably, tannic acid polyphenols ...