Browsing Technological University of the Shannon: Midlands Midwest by Author "Roche, James J."
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Accelerated solvent based extraction and enrichment of selected plasticisers and 4-nonylphenol, and extraction of tin from organotin sources in sediments, sludges and leachate soils.
Reid, Antoinette; Brougham, Concepta; Fogarty, Andrew M; Roche, James J. (Elsevier, 2009-02-23)Enrichment techniques have become an important feature in the trace analysis of oestrogen mimicking chemicals in the environment. Recent developments such as accelerated solvent extraction (ASE) have improved extraction ... -
Advanced therapies and the outer limits of DNA regulation: new horizons for patents or a scaffold too far?
Roche, James J. (Oxford Academic, 2008-04)This Regulation seeks to regulate existing and future advanced therapy medicinal products intended for the market in Member States, being either prepared industrially or manufactured by a method involving an industrial ... -
Analysis of bio-obtainable endocrine disrupting metals in river water and sediment, sewage influent/effluent, sludge, leachate, and concentrated leachate, in the Irish Midlands Shannon catchment.
Reid, Antoinette; Brougham, Concepta; Fogarty, Andrew M; Roche, James J. (Hindawi, 2009-12)The application of an acid digestion and subsequent solid-phase extraction (SPE) procedure were implemented as preliminary treatments prior to quantifying the levels of potentially endocrine disrupting metals (EDMs) in a ... -
Characterisation of biopharmaceuticals
Bradley, Derek; Burke, Mary; Roche, James J. (The Institute of Chemistry of Ireland, 2016-07)Biopharmaceuticals are drugs which are primarily (glyco)protein in nature, that are produced in living cells using recombinant DNA technology – the combination of genetic material from multiple sources, creating sequences ... -
An investigation into possible sources of phthalate contamination in the environmental analytical laboratory.
Reid, Antoinette; Brougham, Concepta; Fogarty, Andrew M.; Roche, James J. (Taylor & Francis Online, 2007-02)A study of common laboratory equipment and components was performed in order to identify sources of contamination of phthalates prior to testing environmental samples for such compounds. A screening study revealed significant ... -
Isocractic LC methods for the trace analysis of phthalates and 4-nonylphenol in varying types of landfill and adjacent run-offs.
Reid, Antoinette; Brougham, Concepta; Fogarty, Andrew M; Roche, James J. (Taylor & Francis Online, 2007-07)To determine the levels of known endocrine disrupting chemicals such as phthalates and alkylphenols in environmental samples such as leachate water and sediment, suitable isocratic high performance liquid chromatographic ... -
UPLC® method development and validation for the assay of the photolabile drug nifedipine and its trace level degradation products.
Phelan, James; Roche, James J. (The Institute of Chemistry of Ireland, 2017-06)Quality assurance regulations require that pharmaceutical drugs are highly pure. This is in order to ensure the safety and efficacy of medicines for patients, two fundamental issues of importance in treatment. The safety ...